Micro ribonucleic acid (microRNA, miRNA, μRNA) are small, single-stranded, non-coding RNA molecules containing 21–23 nucleotides. Found in plants, animals...
147 KB (16,635 words) - 21:40, 7 May 2025
MicroRNA sequencing (miRNA-seq), a type of RNA-Seq, is the use of next-generation sequencing or massively parallel high-throughput DNA sequencing to sequence...
49 KB (5,200 words) - 07:39, 12 December 2023
Regulus Therapeutics (section microRNA explained)
expression. Anti-miR therapeutics inhibit specific microRNA targets. Animal models showed that modulating microRNAs through anti-miRs effectively regulates biological...
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The Let-7 microRNA precursor gives rise to let-7, a microRNA (miRNA) involved in control of stem-cell division and differentiation. let-7, short for "lethal-7"...
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Glioblastoma (section MicroRNA)
the sinuous extracellular matrix of the brain. As of 2012, RNA interference, usually microRNA, was under investigation in tissue culture, pathology specimens...
81 KB (9,104 words) - 20:58, 29 May 2025
ribonucleic acid (RNA) molecules, microRNA (miRNA) and small interfering RNA (siRNA), are central to components to the RNAi pathway. Once mRNA is degraded,...
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Farrell, Jr. RNA Methodologies, 5th Edition. Academic Press, 2017 Brennecke J, Stark A, Russell RB, Cohen SM (March 2005). "Principles of microRNA-target recognition"...
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RNAs such as microRNAs, siRNAs, piRNAs, snoRNAs, snRNAs, exRNAs, scaRNAs and the long ncRNAs such as Xist and HOTAIR. The number of non-coding RNAs within...
67 KB (7,183 words) - 05:31, 23 May 2025
Gary Ruvkun (section microRNA, let-7)
by which lin-4, the first microRNA (miRNA) discovered by Victor Ambros, regulates the translation of target messenger RNAs via imperfect base-pairing...
33 KB (3,186 words) - 18:22, 15 May 2025
a number of specific microRNAs, when overexpressed, that directly reduce expression of specific DNA repair proteins (see MicroRNA section DNA repair and...
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This microRNA database and microRNA targets databases is a compilation of databases and web portals and servers used for microRNAs and their targets....
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MicroRNA 4727 is a microRNA that in humans is produced by the MIR4727 gene. microRNAs (miRNAs) are short (20–24 nt) non-coding RNAs that are involved...
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body-specific RNA, by Dicer. This small RNA was found to function as a microRNA. Potential microRNAs were also identified in several other Human snoRNAs. Giardia...
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example is RNA interference (RNAi), in which endogenously expressed microRNA (miRNA) or exogenously derived small interfering RNA (siRNA) induces the...
48 KB (5,498 words) - 13:11, 28 December 2024
MicroRNA (miRNA) biosensors are analytical devices that involve interactions between the target miRNA strands and recognition element on a detection platform...
64 KB (7,163 words) - 16:16, 22 May 2025
MicroRNA 5008 is a protein that in humans is encoded by the MIR5008 gene. MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in...
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Cancer epigenetics (section MicroRNA gene silencing)
et al. (February 2013). "MicroRNA-182-5p targets a network of genes involved in DNA repair". RNA. 19 (2): 230–242. doi:10.1261/rna.034926.112. PMC 3543090...
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MicroRNA 210 is a protein that in humans is encoded by the MIR210 gene. MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in...
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MicroRNA 7-2 is a non-protein-coding gene product that in humans is encoded by the MIR7-2 gene. microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs...
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MicroRNA 425 is a microRNA that in humans is encoded by the MIR425 gene. "Entrez Gene: MicroRNA 425". Retrieved 2018-10-11. Liang D, Meyer L, Chang DW...
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Gene expression (redirect from RNA expression)
expression of microRNAs. In breast cancer, transcriptional repression of BRCA1 may occur more frequently by over-transcribed microRNA-182 than by hypermethylation...
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P-bodies (section Associations with microRNA)
in general mRNA decay, nonsense-mediated mRNA decay, adenylate-uridylate-rich element mediated mRNA decay, and microRNA (miRNA) induced mRNA silencing....
28 KB (2,093 words) - 18:17, 31 October 2024
MicroRNA 34a (miR-34a) is a microRNA that in humans is encoded by the MIR34A gene. microRNAs (miRNAs) are short (20–24 nt) non-coding RNAs that are involved...
9 KB (1,123 words) - 16:24, 5 August 2024
MicroRNA 495 is a protein that in humans is encoded by the MIR495 gene. microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in...
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encoding microRNA MicroRNA 106 MIR222: encoding microRNA MicroRNA 222 MIR223: encoding protein MicroRNA 223 MIR361: encoding microRNA MicroRNA 361 MIR503:...
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transfer RNA (tRNA), microRNA (miRNA), small interfering RNA (siRNA), small nucleolar RNA (snoRNAs), Piwi-interacting RNA (piRNA), tRNA-derived small RNA (tsRNA)...
65 KB (7,626 words) - 20:44, 25 May 2025
David Baltimore (section MicroRNA Research)
the lab's closure in 2018 was understanding the role of microRNA in the immune system. MicroRNAs provide fine control over gene expression by regulating...
80 KB (8,319 words) - 06:52, 27 May 2025
competitive endogenous RNAs (ceRNAs) act as molecular sponges for a microRNA through their miRNA binding sites (also referred to as miRNA response elements...
25 KB (3,201 words) - 04:38, 19 May 2025
MicroRNA 4521 is a micro RNA that in humans is encoded by the MIR4521 gene. microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved...
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Post-transcriptional regulation (category RNA)
cancers (see DNA repair defect and cancer risk and microRNA and DNA repair). Altered microRNA (miRNA) expression that either decreases accurate DNA repair...
27 KB (3,383 words) - 01:17, 8 September 2024