• Thumbnail for MicroRNA
    Micro ribonucleic acid (microRNA, miRNA, μRNA) are small, single-stranded, non-coding RNA molecules containing 21–23 nucleotides. Found in plants, animals...
    147 KB (16,635 words) - 21:40, 7 May 2025
  • MicroRNA sequencing (miRNA-seq), a type of RNA-Seq, is the use of next-generation sequencing or massively parallel high-throughput DNA sequencing to sequence...
    49 KB (5,200 words) - 07:39, 12 December 2023
  • expression. Anti-miR therapeutics inhibit specific microRNA targets. Animal models showed that modulating microRNAs through anti-miRs effectively regulates biological...
    5 KB (354 words) - 02:19, 24 May 2025
  • The Let-7 microRNA precursor gives rise to let-7, a microRNA (miRNA) involved in control of stem-cell division and differentiation. let-7, short for "lethal-7"...
    72 KB (8,447 words) - 11:23, 22 May 2025
  • Thumbnail for Glioblastoma
    the sinuous extracellular matrix of the brain. As of 2012, RNA interference, usually microRNA, was under investigation in tissue culture, pathology specimens...
    81 KB (9,104 words) - 20:58, 29 May 2025
  • Thumbnail for RNA interference
    ribonucleic acid (RNA) molecules, microRNA (miRNA) and small interfering RNA (siRNA), are central to components to the RNAi pathway. Once mRNA is degraded,...
    140 KB (15,409 words) - 15:05, 22 May 2025
  • Thumbnail for Messenger RNA
    Farrell, Jr. RNA Methodologies, 5th Edition. Academic Press, 2017 Brennecke J, Stark A, Russell RB, Cohen SM (March 2005). "Principles of microRNA-target recognition"...
    51 KB (6,206 words) - 13:31, 24 May 2025
  • Thumbnail for Non-coding RNA
    RNAs such as microRNAs, siRNAs, piRNAs, snoRNAs, snRNAs, exRNAs, scaRNAs and the long ncRNAs such as Xist and HOTAIR. The number of non-coding RNAs within...
    67 KB (7,183 words) - 05:31, 23 May 2025
  • Thumbnail for Gary Ruvkun
    by which lin-4, the first microRNA (miRNA) discovered by Victor Ambros, regulates the translation of target messenger RNAs via imperfect base-pairing...
    33 KB (3,186 words) - 18:22, 15 May 2025
  • Thumbnail for BRCA1
    a number of specific microRNAs, when overexpressed, that directly reduce expression of specific DNA repair proteins (see MicroRNA section DNA repair and...
    121 KB (13,614 words) - 07:52, 19 February 2025
  • This microRNA database and microRNA targets databases is a compilation of databases and web portals and servers used for microRNAs and their targets....
    27 KB (2,020 words) - 08:13, 30 March 2025
  • Thumbnail for MicroRNA 4727
    MicroRNA 4727 is a microRNA that in humans is produced by the MIR4727 gene. microRNAs (miRNAs) are short (20–24 nt) non-coding RNAs that are involved...
    1 KB (215 words) - 02:29, 4 January 2025
  • body-specific RNA, by Dicer. This small RNA was found to function as a microRNA. Potential microRNAs were also identified in several other Human snoRNAs. Giardia...
    5 KB (626 words) - 19:34, 28 August 2023
  • example is RNA interference (RNAi), in which endogenously expressed microRNA (miRNA) or exogenously derived small interfering RNA (siRNA) induces the...
    48 KB (5,498 words) - 13:11, 28 December 2024
  • Thumbnail for MicroRNA biosensors
    MicroRNA (miRNA) biosensors are analytical devices that involve interactions between the target miRNA strands and recognition element on a detection platform...
    64 KB (7,163 words) - 16:16, 22 May 2025
  • Thumbnail for MicroRNA 5008
    MicroRNA 5008 is a protein that in humans is encoded by the MIR5008 gene. MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in...
    2 KB (210 words) - 19:41, 8 April 2022
  • Thumbnail for Cancer epigenetics
    et al. (February 2013). "MicroRNA-182-5p targets a network of genes involved in DNA repair". RNA. 19 (2): 230–242. doi:10.1261/rna.034926.112. PMC 3543090...
    111 KB (12,542 words) - 20:15, 29 May 2025
  • Thumbnail for MicroRNA 210
    MicroRNA 210 is a protein that in humans is encoded by the MIR210 gene. MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in...
    5 KB (686 words) - 11:12, 6 November 2024
  • Thumbnail for MicroRNA 7-2
    MicroRNA 7-2 is a non-protein-coding gene product that in humans is encoded by the MIR7-2 gene. microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs...
    2 KB (267 words) - 04:56, 22 January 2021
  • MicroRNA 425 is a microRNA that in humans is encoded by the MIR425 gene. "Entrez Gene: MicroRNA 425". Retrieved 2018-10-11. Liang D, Meyer L, Chang DW...
    4 KB (546 words) - 23:12, 8 November 2024
  • Thumbnail for Gene expression
    expression of microRNAs. In breast cancer, transcriptional repression of BRCA1 may occur more frequently by over-transcribed microRNA-182 than by hypermethylation...
    104 KB (11,643 words) - 09:45, 24 May 2025
  • in general mRNA decay, nonsense-mediated mRNA decay, adenylate-uridylate-rich element mediated mRNA decay, and microRNA (miRNA) induced mRNA silencing....
    28 KB (2,093 words) - 18:17, 31 October 2024
  • Thumbnail for MIR34A
    MicroRNA 34a (miR-34a) is a microRNA that in humans is encoded by the MIR34A gene. microRNAs (miRNAs) are short (20–24 nt) non-coding RNAs that are involved...
    9 KB (1,123 words) - 16:24, 5 August 2024
  • Thumbnail for MicroRNA 495
    MicroRNA 495 is a protein that in humans is encoded by the MIR495 gene. microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in...
    5 KB (761 words) - 07:21, 3 December 2023
  • Thumbnail for X chromosome
    encoding microRNA MicroRNA 106 MIR222: encoding microRNA MicroRNA 222 MIR223: encoding protein MicroRNA 223 MIR361: encoding microRNA MicroRNA 361 MIR503:...
    43 KB (3,981 words) - 09:57, 13 March 2025
  • Thumbnail for RNA
    transfer RNA (tRNA), microRNA (miRNA), small interfering RNA (siRNA), small nucleolar RNA (snoRNAs), Piwi-interacting RNA (piRNA), tRNA-derived small RNA (tsRNA)...
    65 KB (7,626 words) - 20:44, 25 May 2025
  • Thumbnail for David Baltimore
    the lab's closure in 2018 was understanding the role of microRNA in the immune system. MicroRNAs provide fine control over gene expression by regulating...
    80 KB (8,319 words) - 06:52, 27 May 2025
  • competitive endogenous RNAs (ceRNAs) act as molecular sponges for a microRNA through their miRNA binding sites (also referred to as miRNA response elements...
    25 KB (3,201 words) - 04:38, 19 May 2025
  • Thumbnail for MicroRNA 4521
    MicroRNA 4521 is a micro RNA that in humans is encoded by the MIR4521 gene. microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved...
    2 KB (288 words) - 00:24, 19 September 2024
  • cancers (see DNA repair defect and cancer risk and microRNA and DNA repair). Altered microRNA (miRNA) expression that either decreases accurate DNA repair...
    27 KB (3,383 words) - 01:17, 8 September 2024