• Thumbnail for Modafinil
    Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant and eugeroic (wakefulness promoter) medication...
    179 KB (16,512 words) - 15:12, 5 June 2025
  • Thumbnail for Adrafinil
    Adrafinil (category Modafinil analogues)
    is primarily metabolized in vivo to modafinil, resulting in very similar pharmacological effects. Unlike modafinil, however, it takes time for the metabolite...
    22 KB (2,055 words) - 18:27, 10 June 2025
  • Thumbnail for Stimulant
    Stimulant (section Modafinil)
    include caffeine, nicotine, amphetamines, cocaine, methylphenidate, and modafinil. Stimulants may be subject to varying forms of regulation, or outright...
    129 KB (13,209 words) - 09:55, 7 June 2025
  • Thumbnail for List of modafinil analogues and derivatives
    compounds similar to modafinil, known as modafinil analogues and derivatives. These are structural analogues and derivatives of modafinil, a drug that affects...
    36 KB (3,562 words) - 06:44, 2 June 2025
  • Thumbnail for Armodafinil
    Armodafinil (redirect from R-modafinil)
    enantiopure (R)-(–)-enantiomer of the racemic mixture modafinil (brand name Provigil). Both enantiomers of modafinil are active as DRIs and wakefulness-promoting...
    29 KB (2,414 words) - 09:53, 9 June 2025
  • Thumbnail for Nootropic
    effects of modafinil were examined, when simple psychometric assessments were considered, modafinil intake enhanced executive function. Modafinil does not...
    34 KB (3,368 words) - 15:00, 31 May 2025
  • Thumbnail for Modafinil sulfone
    metabolites of modafinil, the other being modafinil acid. Modafinil sulfone is also a metabolite of the modafinil prodrug, adrafinil. Modafinil sulfone is...
    4 KB (352 words) - 17:18, 12 October 2024
  • Thumbnail for Eugeroic
    both for modafinil-type drugs and other agents. Eugeroics, in the sense of modafinil-type wakefulness promoting agents, include modafinil itself, armodafinil...
    19 KB (1,937 words) - 20:48, 29 May 2025
  • Thumbnail for Flmodafinil
    Flmodafinil (category Modafinil analogues)
    bisfluoromodafinil and lauflumide, is a wakefulness-promoting agent related to modafinil which has been developed for treatment of a variety of different medical...
    18 KB (1,750 words) - 04:01, 6 January 2025
  • Thumbnail for Modafinil acid
    Modafinil acid (code name CRL-40467), also known as modafinilic acid or modafinil carboxylate, is one of the two major metabolites of modafinil – the...
    6 KB (527 words) - 17:18, 12 October 2024
  • Thumbnail for Narcolepsy
    EDS and/or cataplexy. These medications include alerting agents (e.g., modafinil, armodafinil, pitolisant, solriamfetol), oxybate medications (e.g., twice...
    72 KB (8,174 words) - 13:04, 2 June 2025
  • neuroenhancement agents may include compounds thought to be nootropics, such as modafinil, caffeine, and other drugs used for treating people with neurological...
    26 KB (2,483 words) - 00:07, 24 May 2025
  • transporters) Armodafinil (R-enantiomer of modafinil; somewhat more potent at inhibiting DAT than racemic modafinil, with equally negligible action on NET...
    19 KB (1,930 words) - 22:33, 23 May 2025
  • Thumbnail for Fladrafinil
    Fladrafinil (category Modafinil analogues)
    agent related to modafinil that was never marketed. It is sold online and used non-medically as a nootropic (cognitive enhancer). Modafinil and its analogues...
    7 KB (556 words) - 07:18, 6 January 2025
  • Thumbnail for Danavorexton
    found to dose-dependently produce wakefulness to a similar degree as modafinil in a phase 1 clinical trial. As of March 2021, danavorexton is under development...
    5 KB (301 words) - 01:41, 22 September 2024
  • sanctioned recreational drug use.[citation needed] Modafinil (when used off-label or for shift-work); Modafinil is indicated for the treatment shift-work sleep...
    9 KB (999 words) - 14:39, 3 December 2023
  • compared to the results of modafinil and placebo to assess efficacy (e.g. methylphenidate in Parkinson's Disease). Modafinil is also being tested across...
    31 KB (3,612 words) - 11:12, 3 June 2025
  • Thumbnail for Fluorenol
    successor to the eugeroic modafinil reported that the corresponding fluorenol derivative was 39% more effective than modafinil at keeping mice awake over...
    8 KB (687 words) - 18:26, 9 June 2025
  • Thumbnail for Esmodafinil
    Esmodafinil (category Modafinil analogues)
    (also known as (S)-modafinil or (+)-modafinil; developmental code name CRL-40983) is the enantiopure (S)-(+)-enantiomer of modafinil. Unlike armodafinil...
    8 KB (595 words) - 17:18, 12 October 2024
  • underlying disorder which may cure the person from the EDS. Drugs like modafinil, armodafinil, pitolisant (Wakix), sodium oxybate (Xyrem) oral solution...
    19 KB (1,827 words) - 14:12, 24 May 2025
  • 2022-12-26. Wheeler B (October 26, 2006). "BBC report on MoD research into modafinil". BBC News. Retrieved July 4, 2012. "MoD's secret pep pill to keep forces...
    19 KB (1,262 words) - 07:08, 13 May 2025
  • Thumbnail for (S)-MK-26
    (S)-MK-26 (category Modafinil analogues)
    reuptake inhibitor (DRI) that was derived from modafinil. It is closely related to two other modafinil analogues, (S,S)-CE-158 and (S)-CE-123. (S)-MK-26...
    6 KB (364 words) - 05:12, 11 November 2024
  • Thumbnail for JJC8-088
    JJC8-088 (category Modafinil analogues)
    wakefulness-promoting agent modafinil. It has substantially higher affinity for the dopamine transporter (DAT) than modafinil (Ki = 6.72 nM vs. 2,600 nM;...
    8 KB (719 words) - 14:24, 8 June 2025
  • Thumbnail for Modafiendz
    Modafiendz (category Modafinil analogues)
    N-methylbisfluoromodafinil, is a wakefulness-promoting agent related to modafinil that was never marketed. It is sold online and used non-medically as a...
    6 KB (486 words) - 17:19, 12 October 2024
  • attention/persistence). Pseudoephedrine and ephedrine do not affect ADHD symptoms. Modafinil has shown some efficacy in reducing the severity of ADHD in children and...
    274 KB (29,035 words) - 17:13, 17 June 2025
  • Thumbnail for Seasonal affective disorder
    lack of evidence, and the need for larger randomized controlled trials. Modafinil may be an effective and well-tolerated treatment in patients with seasonal...
    50 KB (5,606 words) - 09:51, 9 June 2025
  • Thumbnail for JJC8-016
    JJC8-016 (category Modafinil analogues)
    dopamine reuptake inhibitor (DRI) derived from modafinil. It was an early lead in the development of novel modafinil analogues with improved properties for potential...
    12 KB (1,068 words) - 14:11, 6 June 2025
  • Thumbnail for RDS03-94
    RDS03-94 (category Modafinil analogues)
    wakefulness-promoting agent modafinil. It has substantially higher affinity and potency in terms of dopamine transporter (DAT) inhibition than modafinil (Ki = 39.4 nM...
    7 KB (526 words) - 07:46, 7 April 2025
  • Thumbnail for Ketamine
    stimulated by phencyclidines, lysergic acid diethylamide, salvinorin A, and modafinil". Synapse. 63 (8): 698–704. doi:10.1002/syn.20647. PMID 19391150. S2CID 17758902...
    119 KB (11,478 words) - 03:09, 13 June 2025
  • Thumbnail for CE-158
    CE-158 (category Modafinil analogues)
    is an atypical dopamine reuptake inhibitor (DRI) that was derived from modafinil. It is often but not always referred to as the enantiopure enantiomer...
    9 KB (884 words) - 07:19, 20 February 2025