molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information...

General transcription factors (GTFs), also known as basal transcriptional factors, are a class of protein transcription factors that bind to specific...

by an inactive transcription factor. Phosphorylation of the transcription factor may activate it and that activated transcription factor may then activate...

Transcription factor Jun is a protein that in humans is encoded by the JUN gene. c-Jun, in combination with protein c-Fos, forms the AP-1 early response...

Transcription factor Sp1, also known as specificity protein 1* is a protein that in humans is encoded by the SP1 gene. The protein encoded by this gene...

(AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and...

T-box transcription factor T, also known as Brachyury protein, is encoded for in humans and other apes by the TBXT gene. Brachyury functions as a transcription...

This list of manually curated human transcription factors is taken from Lambert, Jolma, Campitelli et al. It was assembled by manual curation. More detailed...

biology. The regulation of transcription is a vital process in all living organisms. It is orchestrated by transcription factors and other proteins working...

regulate. CREs typically regulate gene transcription by binding to transcription factors. A single transcription factor may bind to many CREs, and hence control...

The fluffy (fl) gene of Neurospora crassa is required for asexual sporulation and encodes an 88 kDa polypeptide containing a typical fungal Zn2Cys6 DNA-binding...

Microphthalmia-associated transcription factor also known as class E basic helix-loop-helix protein 32 or bHLHe32 is a protein that in humans is encoded...

promoters. General transcription factors are a group of proteins involved in transcription initiation and regulation. These factors typically have DNA-binding...

sigma factor (σ factor or specificity factor) is a protein needed for initiation of transcription in bacteria. It is a bacterial transcription initiation...

The Gal4 transcription factor is a positive regulator of gene expression of galactose-induced genes. This protein represents a large fungal family of transcription...

Escargot (esg) is a transcription factor expressed in Drosophila melanogaster. It is responsible for the maintenance of intestinal stem cells and is used...

Transcription factor II B (TFIIB) is a general transcription factor that is involved in the formation of the RNA polymerase II preinitiation complex (PIC)...

A ρ factor (Rho factor) is a bacterial protein involved in the termination of transcription. Rho factor binds to the transcription terminator pause site...

Transformation Specific) family is one of the largest families of transcription factors and is unique to animals. There are 28 genes in humans, 27 in the...

polymerase II active site for transcription. The minimal PIC includes RNA polymerase II and six general transcription factors: TFIIA, TFIIB, TFIID, TFIIE...

by regio/stereoselective Michael addition to ring A. NF-κB is a transcription factor that regulates many genes involved in cell survival, growth, immune...

molecular biology, transcription factor DP (Dimerization Partner) is a family of proteins which function as transcription factors. DP forms a heterodimer...

identified in 1989 as general transcription factor-δ or basic transcription factor 2, an essential factor for transcription in vitro. It was subsequently...

polymerase and for proteins called transcription factors that recruit RNA polymerase. These transcription factors have specific activator or repressor...

(SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein/transcription factor) encoded by the SRY gene that...

Transcription factor II D (TFIID) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. RNA polymerase...

Thiele DJ (June 2001). "The Candida glabrata Amt1 copper-sensing transcription factor requires Swi/Snf and Gcn5 at a critical step in copper detoxification"...

eukaryotes. Homeobox genes encode homeodomain protein products that are transcription factors sharing a characteristic protein fold structure that binds DNA to...

finger transcription factors or ZF-TFs, are transcription factors composed of a zinc finger-binding domain and any of a variety of transcription-factor effector-domains...

POLR2F form homodimers). General transcription factors (GTFs) or basal transcription factors are protein transcription factors that have been shown to be important...