• Thumbnail for 4-Hydroxytryptamine
    4-Hydroxytryptamine (4-HT, 4-HTA), also known as N,N-didesmethylpsilocin, is a naturally occurring tryptamine alkaloid. It is closely related chemically...
    16 KB (1,403 words) - 00:15, 18 June 2025
  • Thumbnail for 6-Hydroxytryptamine
    positional isomer of serotonin (5-hydroxytryptamine; 5-HT) and of 4-hydroxytryptamine (4-HT). 6-Hydroxytryptamine shows dramatically reduced affinity...
    9 KB (791 words) - 07:15, 22 June 2025
  • Thumbnail for 4-Methoxytryptamine
    4-Methoxytryptamine (4-MeO-T; developmental code name PAL-548) is a serotonin receptor modulator of the tryptamine and 4-hydroxytryptamine families. It...
    4 KB (233 words) - 04:47, 19 June 2025
  • Thumbnail for Serotonin
    Serotonin (/ˌsɛrəˈtoʊnɪn, ˌsɪərə-/), also known as 5-hydroxytryptamine (5-HT), is a monoamine neurotransmitter with a wide range of functions in both...
    173 KB (18,295 words) - 19:45, 2 June 2025
  • Thumbnail for 4-MeO-DMT
    psychedelic drug of the tryptamine and 4-hydroxytryptamine families. It is the O-methylated analogue of psilocin (4-HO-DMT) and a positional isomer of 5-MeO-DMT...
    13 KB (1,142 words) - 22:58, 18 June 2025
  • Thumbnail for 4-Hydroxy-5-methoxytryptamine
    structurally related to the monoamine neurotransmitter serotonin (5-hydroxytryptamine; 5-HT). The drug is also a monoamine reuptake inhibitor. Its analogue...
    3 KB (178 words) - 17:23, 27 March 2025
  • Thumbnail for Psilocin
    Psilocin (redirect from 4-HO-DMT)
    is structurally similar to serotonin (5-hydroxytryptamine), differing only by the hydroxyl group being on the 4-position rather than the 5 and the dimethyl...
    28 KB (3,019 words) - 03:35, 15 June 2025
  • Thumbnail for 4-AcO-DMT
    3-[2-(dimethylamino)ethyl]-1H-indol-4-ol::4-hydroxy-N,N-dimethyltryptamine::CHEMBL65547::N,N-dimethyl-4-hydroxytryptamine::Psilocin::US11427604, Compound...
    30 KB (3,627 words) - 03:17, 13 June 2025
  • Thumbnail for 4-HO-MET
    (April 2023). "Pharmacologic Activity of Substituted Tryptamines at 5-Hydroxytryptamine (5-HT)2A Receptor (5-HT2AR), 5-HT2CR, 5-HT1AR, and Serotonin Transporter"...
    20 KB (1,288 words) - 02:34, 31 May 2025
  • Thumbnail for 4-HO-DALT
    receptor agonist and serotonergic psychedelic of the tryptamine and 4-hydroxytryptamine families. It binds to many of the serotonin receptors, including...
    6 KB (422 words) - 00:10, 11 April 2025
  • of nicotine FAEFHI 4-Methylaminorex PIM-35 Hydroxytryptamine Serotonin (5-Hydroxytryptamine) 4-Hydroxytryptamine 6-Hydroxytryptamine This set index page...
    474 bytes (77 words) - 02:44, 27 June 2025
  • Thumbnail for Psilocybin mushroom
    psilocybin and psilocin equivalence, psilocin is about 1.4-fold more potent than psilocybin (i.e., 1.4 mg psilocybin equals about 1.0 mg psilocin), which is...
    67 KB (6,965 words) - 20:27, 19 June 2025
  • Thumbnail for Norbaeocystin
    Norbaeocystin (category 4-Phosphoryloxytryptamines)
    phosphorylated derivative of 4-hydroxytryptamine (4-HT). The latter is notable as a positional isomer of serotonin, which is 5-hydroxytryptamine. Norbaeocystin is...
    5 KB (357 words) - 00:34, 11 April 2025
  • Thumbnail for 4-HO-MiPT
    Federal Analog Act. 4-HO-MiPT is in Schedule 1 in Russia as an analog of 4-hydroxytryptamine. MiPT 4-AcO-MiPT 4-HO-EiBT 4-HO-McPT 4-MeO-MiPT 5-MeO-MiPT...
    10 KB (779 words) - 00:11, 11 April 2025
  • Thumbnail for RE-104
    Neuroscience. RE104 a prodrug ester of a synthetic psychedelic 4-hydroxytryptamine, 4-HO-DiPT. It is one of a number of related psychedelic derivatives...
    10 KB (830 words) - 00:35, 11 April 2025
  • Thumbnail for 4-HO-DiPT
    (April 2023). "Pharmacologic Activity of Substituted Tryptamines at 5-Hydroxytryptamine (5-HT)2A Receptor (5-HT2AR), 5-HT2CR, 5-HT1AR, and Serotonin Transporter"...
    19 KB (1,196 words) - 00:30, 15 May 2025
  • Thumbnail for 4-HO-NALT
    derivatives (4-HO-NET, 4-HO-NPT, 4-HO-NiPT and 4-HO-NBnT), but the bulkier t-butyl and cyclohexyl derivatives are inactive. 4-AcO-DALT 4-HO-MALT 5-HO-DiPT...
    2 KB (116 words) - 21:49, 20 June 2025
  • Thumbnail for 4-HO-DET
    (April 2023). "Pharmacologic Activity of Substituted Tryptamines at 5-Hydroxytryptamine (5-HT)2A Receptor (5-HT2AR), 5-HT2CR, 5-HT1AR, and Serotonin Transporter"...
    9 KB (648 words) - 09:36, 24 May 2025
  • Thumbnail for 4-PrO-DMT
    3-[2-(dimethylamino)ethyl]-1H-indol-4-ol::4-hydroxy-N,N-dimethyltryptamine::CHEMBL65547::N,N-dimethyl-4-hydroxytryptamine::Psilocin::US11427604, Compound...
    6 KB (1,093 words) - 05:16, 28 May 2025
  • Thumbnail for Psilomethoxin
    Psilomethoxin (redirect from 4-HO-5-MeO-DMT)
    HG, Schlosserberger HG (July 1973). "Inhibition of the uptake of 5-hydroxytryptamine, noradrenaline and dopamine into rat brain homogenates by various...
    14 KB (1,524 words) - 03:04, 11 April 2025
  • Thumbnail for 5-HO-DPT
    5-HO-DPT (category 5-Hydroxytryptamines)
    modulator of the tryptamine and 5-hydroxytryptamine families. It is the N,N-dipropyl derivative of serotonin (5-hydroxytryptamine; 5-HT). The drug shows affinity...
    4 KB (287 words) - 04:42, 19 June 2025
  • Thumbnail for 4-HO-EiBT
    EC50 of 27.7 nM and an efficacy of 97.5% (vs 5-HT). 4-HO-DiPT 4-HO-DSBT 4-HO-McPT 4-HO-McPeT 4-HO-MiPT 4-HO-PiPT WO 2023/115167, Banister S, Jorgensen W,...
    1 KB (83 words) - 02:21, 13 May 2025
  • Thumbnail for L-Tryptophan decarboxylase
    L-Tryptophan decarboxylase (category EC 4.1.1)
    follows: L-Tryptophan is decarboxylated to 4-hydroxytryptamine by psiD → psiK phosphorylates 4-hydroxytryptamine to create norbaeocystin → psiM then processively...
    13 KB (1,331 words) - 10:08, 24 August 2023
  • Thumbnail for Norpsilocin
    Norpsilocin (redirect from 4-HO-NMT)
    in children. 4-HO-NALT 4-Hydroxytryptamine Lenz C, Wick J, Hoffmeister D (October 2017). "Identification of ω-N-Methyl-4-hydroxytryptamine (Norpsilocin)...
    8 KB (659 words) - 08:16, 27 March 2025
  • Thumbnail for Methylxanthines
    Tryptamines α-Alkyltryptamines α-Alkyl-β-ketotryptamines 4-Hydroxytryptamines 5-Hydroxytryptamines 5-Methoxytryptamines Miscellaneous Dissociatives/NMDA...
    826 bytes (98 words) - 13:09, 30 March 2025
  • Thumbnail for 2C-B
    hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors". The Journal of Pharmacology and Experimental...
    57 KB (5,519 words) - 00:11, 24 June 2025
  • investigations revealed an enhancement of activity by nitration of the 5-position. 4'-Methoxylated and ethoxylated compounds achieved potencies in the hot plate...
    8 KB (908 words) - 05:03, 11 May 2025
  • Thumbnail for 4-HO-McPT
    4-HO-McPT (4-hydroxy-N-methyl-N-cyclopropyltryptamine) is a psychedelic tryptamine derivative. It has serotonergic effects, and has reportedly been sold...
    3 KB (132 words) - 15:44, 9 May 2025
  • Thumbnail for Substituted tryptamine
    or simply tryptamines, also known as serotonin analogues (i.e., 5-hydroxytryptamine analogues), are organic compounds which may be thought of as being...
    83 KB (2,418 words) - 05:29, 17 June 2025
  • Thumbnail for 5-HT2A receptor
    (April 2013). "5-Hydroxytryptamine 2A receptor antagonists as potential treatment for psychiatric disorders". Expert Opin Investig Drugs. 22 (4): 411–421. doi:10...
    131 KB (13,680 words) - 11:36, 9 June 2025