APOBEC ("apolipoprotein B mRNA editing enzyme, catalytic polypeptide") is a family of evolutionarily conserved cytidine deaminases. A mechanism of generating...

C->U-editing enzyme APOBEC-1 is a protein that in humans is encoded by the APOBEC1 gene. This gene encodes a member of the APOBEC protein family and the...

B mRNA editing enzyme, catalytic polypeptide 1 (ApoBEC-1) as well as other auxiliary factors. ApoBEC-1 is a protein that in humans is encoded by the APOBEC1...

antigens. APOBEC family can also protect against the infection of RNA retroviruses and retrotransposons. In a single-strand DNA (ssDNA), APOBEC can transfer...

enzymes (cytidine deaminase/CDA, activation-induced cytidine deaminase and APOBEC protein family) actively cause cytidine deamination and therefore introduce...

base. Active enzymatic deamination of cytosine or 5-methylcytosine by the APOBEC family of cytosine deaminases could have both beneficial and detrimental...

3G) is a human enzyme encoded by the APOBEC3G gene that belongs to the APOBEC superfamily of proteins. This family of proteins has been suggested to play...

enzyme APOBEC (specifically APOBEC3G, "A3G" in short, and other A3 enzymes) by targeting it for ubiquitination and cellular degradation. APOBEC is a cytidine...

viruses. APOBEC is a family of cytidine deaminases (enzymes) that are expressed in cells that are susceptible to HIV-1. She has shown that APOBEC Complex...

DNA dC->dU-editing enzyme APOBEC-3H, also known as Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H or APOBEC-related protein 10, is a...

important in the innate immune defense against retroviruses, along with the APOBEC family of proteins, tetherin and TRIM22. TRIM5α belongs to the TRIM protein...

an apolipoprotein B RNA-binding protein that interacts with both apobec-1 and apobec-1 complementation factor to modulate C to U editing". J. Biol. Chem...

generates other types of mutations, such as C:G to A:T. AID is a member of the APOBEC family. In B cells in the lymph nodes, AID causes mutations that produce...

activity-induced cytidine deaminase/apolipoprotein B mRNA editing complex (AID/APOBEC) deaminases to form 5-hydroxymethyluracil (5hmU) or 5mC can be converted...

and epigenetic, are collectively called dual inheritance. Members of the APOBEC/AID family of cytosine deaminases may concurrently influence genetic and...

Probable C->U-editing enzyme APOBEC-2 is a protein that in humans is encoded by the APOBEC2 gene. GRCh38: Ensembl release 89: ENSG00000124701 – Ensembl...

Probable DNA dC->dU-editing enzyme APOBEC-3B is a protein that in humans is encoded by the APOBEC3B gene. This gene is a member of the cytidine deaminase...

presumptive apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like (APOBEC)s expressed in lymphocytes—CDA1 and CDA2—have been discovered in P. marinus...

Cervantes-Gracia K, Gramalla-Schmitz A, Weischedel J, Chahwan R (2021). "APOBECs orchestrate genomic and epigenomic editing across health and disease"....

C->U-editing enzyme APOBEC-4, also known as Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4, is a protein that in humans is encoded by...

coding for VLRs can be altered by a family of cytidine deaminases known as APOBEC, possibly through gene conversion. Cytidine deaminase 1 is associated with...

activity-induced cytidine deaminase/apolipoprotein B mRNA editing complex (AID/APOBEC) deaminases to form 5-hydroxymethyluracil (5hmU) or 5mC can be converted...

diversification of lamprey antigen receptors: evidence for involvement of an AID-APOBEC family cytosine deaminase". Nature Immunology. 8 (6): 647–56. doi:10.1038/ni1463...

alternative enzymatic approach to minimize DNA damage. Instead of bisulfite, APOBEC is used to convert C into U. Distinction between C, 5mC, and 5hmC is granted...

activity-induced cytidine deaminase/apolipoprotein B mRNA editing complex (AID/APOBEC) deaminases to form 5-hydroxymethyluracil (5hmU) or 5mC can be converted...

cytosines from subsequent deamination. Deamination of unmodified cytosines: An APOBEC (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-like) deaminase...

PMID 8895530. Lau PP, Zhu HJ, Nakamuta M, Chan L (January 1997). "Cloning of an Apobec-1-binding protein that also interacts with apolipoprotein B mRNA and evidence...

protein ADM2 APOBEC3B: encoding protein probable DNA dC->dU-editing enzyme APOBEC-3B ARFGAP3: encoding protein ADP-ribosylation factor GTPase-activating protein...

acidic pH, with maximal catalytic activity at pH 5.5. Another protein of the APOBEC family very similar to A3A, APOBEC3B, showed little activity at pH 4.5 and...

C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor". J. Biol. Chem. 276 (50). United States:...