• Thumbnail for Adaptor hypothesis
    The adaptor hypothesis is a theoretical scheme in molecular biology to explain how information encoded in the nucleic acid sequences of messenger RNA (mRNA)...
    25 KB (3,238 words) - 19:09, 23 May 2025
  • document of the RNA Tie Club was Francis Crick's adaptor hypothesis in 1955. Experimental work on the hypothesis led to the discovery of transfer RNA, a molecule...
    16 KB (1,813 words) - 21:05, 24 May 2025
  • Thumbnail for Genetic code
    presented a type-written paper titled "On Degenerate Templates and the Adaptor Hypothesis: A Note for the RNA Tie Club" to the members of the club in January...
    74 KB (8,069 words) - 18:49, 23 May 2025
  • Thumbnail for Francis Crick
    the original on 12 September 2005. "On Degenerate Templates and the Adaptor Hypothesis: A Note for the RNA Tie Club" by Francis Crick (1956). Cobb M (29...
    113 KB (13,711 words) - 03:53, 17 May 2025
  • Thumbnail for Wobble base pair
    doi:10.1016/0014-5793(96)00339-0. PMID 8641457. tRNA, the Adaptor Hypothesis and the Wobble Hypothesis Wobble base-pairing between codons and anticodons Genetic...
    13 KB (1,455 words) - 13:19, 5 October 2024
  • Thumbnail for DNA
    relationship between DNA, RNA, and proteins, and articulated the "adaptor hypothesis". Final confirmation of the replication mechanism that was implied...
    167 KB (17,915 words) - 22:22, 29 May 2025
  • Thumbnail for Sydney Brenner
    genetic information from RNA to proteins. Brenner gave the name "adaptor hypothesis" in 1955. The physical separation between the anticodon and the amino...
    46 KB (4,147 words) - 13:40, 3 May 2025
  • Thumbnail for Transfer RNA
    (tRNA), formerly referred to as soluble ribonucleic acid (sRNA), is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides in length (in...
    69 KB (8,264 words) - 15:28, 23 May 2025
  • Thumbnail for MRC Laboratory of Molecular Biology
    time, the central dogma of molecular biology, the sequence hypothesis and the adaptor hypothesis. In 1961 Brenner helped discover messenger RNA and, in the...
    33 KB (3,809 words) - 03:03, 28 May 2025
  • During activation, the tRNA functions as an adaptor molecule, as posited by Francis Crick’s adaptor hypothesis. That is, the tRNA binds at one end to the...
    12 KB (1,610 words) - 14:15, 17 March 2025
  • Thumbnail for Alfred G. Gilman
    science at Yale University. His first research project was to test the adaptor hypothesis of Francis Crick. He worked in the laboratory of Melvin Simpson, where...
    35 KB (3,671 words) - 23:32, 14 May 2025
  • Thumbnail for Glutamine—tRNA ligase
    Becker HD, Stathopoulos C, Tumbula DL, Söll D (July 2000). "The Adaptor hypothesis revisited". Trends in Biochemical Sciences. 25 (7): 311–316. doi:10...
    8 KB (775 words) - 23:24, 27 May 2025
  • Thumbnail for Abiogenesis
    non-living matter, such as simple organic compounds. The prevailing scientific hypothesis is that the transition from non-living to living entities on Earth was...
    202 KB (20,664 words) - 00:26, 28 May 2025
  • cAMP-dependent pathway Ca2+ signaling Lipid signaling Assistants: Signal transducing adaptor protein Scaffold protein...
    18 KB (2,105 words) - 01:40, 20 August 2024
  • by the intended audience. This is because their nonverbal cues, such as adaptor gestures, sweating, kinesic behaviors, verbal disfluencies, etc., tend...
    24 KB (2,788 words) - 19:08, 23 May 2025
  • Thumbnail for Frank–Ter Haar syndrome
    Cejudo-Martin P, de Brouwer A, et al. (February 2010). "Disruption of the podosome adaptor protein Tks4 (SH3PXD2B) causes the skeletal dysplasia, eye, and cardiac...
    5 KB (510 words) - 22:39, 23 October 2024
  • Thumbnail for AK-74
    various muzzle devices such as the standard muzzle brake or a blank-firing adaptor, while a spring-loaded detent pin held in the front sight post prevents...
    95 KB (9,306 words) - 17:18, 28 May 2025
  • template with adaptors that contain a tailor of thymine. Furthermore, the use of these T-tailed adaptors prevents the formation of adaptor dimers. The type...
    43 KB (5,955 words) - 15:52, 22 November 2024
  • Thumbnail for SV40
    ER membrane and get extracted into the cytosol. A dynein motor complex adaptor, BICD2, disassembles the virion further, before components of the LINC...
    21 KB (2,521 words) - 00:17, 7 May 2025
  • Thumbnail for CRISPR
    enzymes are classified as type V restriction enzymes. The cas genes in the adaptor and effector modules of the CRISPR-Cas system are believed to have evolved...
    115 KB (11,900 words) - 23:21, 29 May 2025
  • Thumbnail for Tau protein
    also suggest that it has some similarities to prion proteins. The tau hypothesis states that excessive or abnormal phosphorylation of tau results in the...
    58 KB (6,566 words) - 19:36, 23 May 2025
  • Thumbnail for Receptor-mediated endocytosis
    on the cell plasma membrane. The ligand and receptor will then recruit adaptor proteins and clathrin triskelions to the plasma membrane around where invagination...
    10 KB (1,097 words) - 15:05, 10 January 2025
  • on CCVs are primarily of clathrin, adaptor protein (AP) complexes, and alternative adaptors. Her working hypothesis is that for each trafficking pathway...
    15 KB (1,587 words) - 02:38, 28 April 2025
  • Thumbnail for Caspase 1
    interaction is direct, meaning there is no adaptor protein in the complex. There are a variety of sensor and adaptor proteins, the various combinations of...
    21 KB (2,395 words) - 06:31, 26 January 2025
  • Thumbnail for SNARE protein
    membrane. After fusion, the cis-SNARE complex is bound and disassembled by an adaptor protein, alpha-SNAP. Then, the hexameric ATPase (of the AAA type) called...
    54 KB (6,592 words) - 13:34, 24 May 2025
  • Thumbnail for Lederbergvirus P22
    two non-equivalent sets of six gp4 proteins. Gp4 acts as a structural adaptor for gp10 and gp26, the other tail accessory factors. Transduction has been...
    11 KB (1,284 words) - 10:05, 10 May 2025
  • different adaptors: these adaptors bind randomly the fragment and it can then be amplified. The fragment that does not contain both adaptors cannot be...
    21 KB (2,780 words) - 13:13, 16 December 2023
  • major histocompatibility complex II (MHC II), ionized calcium binding adaptor-1 (IBA1), CD86, ED1 macrophage antigen, CD4, and leukocyte common antigen...
    44 KB (5,086 words) - 19:09, 23 May 2025
  • Thumbnail for Synaptic pruning
    phosphorylation of ephrin-B3. Ensuing binding of ephrin-B3 to the cytoplasmic adaptor protein, Grb4, leads to the recruitment and binding of Dock180 and p21...
    25 KB (3,156 words) - 20:58, 3 May 2025
  • having histone acetylase activity, e.g., HAT subunit, hADA3 may act as an adaptor protein linking transcription factors with other HAT complexes. In the...
    50 KB (5,523 words) - 18:34, 22 May 2025