Adenosine deaminase (also known as adenosine aminohydrolase, or ADA) is an enzyme (EC 3.5.4.4) involved in purine metabolism. It is needed for the breakdown...

Adenosine deaminase deficiency (ADA deficiency) is a metabolic disorder that causes immunodeficiency. It is caused by mutations in the ADA gene. It accounts...

deaminase (AICDA) Cytidine deaminase (CDA) dCMP deaminase (DCTD) AMP deaminase (AMPD1) Adenosine Deaminase acting on tRNA (ADAT) Adenosine Deaminase acting...

double-stranded RNA-specific adenosine deaminase enzyme family are encoded by the ADAR family genes. ADAR stands for adenosine deaminase acting on RNA. This article...

is possible other pathways exist. When adenosine enters the circulation, it is broken down by adenosine deaminase, which is present in red blood cells and...

Adenosine monophosphate deaminase deficiency type 1 or AMPD1, is a human metabolic disorder in which the body consistently lacks the enzyme AMP deaminase...

Deficiency of Adenosine deaminase 2 (DADA2) is a monogenic disease associated with systemic inflammation and vasculopathy that affects a wide variety...

her white blood cells, and used a retrovirus to insert a healthy adenosine deaminase (ADA) gene into them. These cells were then injected back into her...

5'-nucleotidase. The nucleoside, adenosine, is then deaminated and hydrolyzed to form hypoxanthine via adenosine deaminase and nucleosidase respectively...

absence of adenosine deaminase (ADA) it accumulates in T lymphocytes and kills these cells resulting in a genetic disorder known as adenosine deaminase severe...

In molecular biology, the protein domain Adenosine deaminase z-alpha domain refers to an evolutionary conserved protein domain. This family consists of...

DeSilva received treatment for a genetic defect that left her with adenosine deaminase deficiency (ADA-SCID), a severe immune system deficiency. The defective...

medication used to treat severe combined immunodeficiency due to adenosine deaminase deficiency (ADA-SCID). ADA-SCID is a rare inherited condition in...

In enzymology, an adenosine-phosphate deaminase (EC 3.5.4.17) is an enzyme that catalyzes the chemical reaction 5'-AMP + H2O ⇌ {\displaystyle \rightleftharpoons...

Dipeptidyl peptidase-4 (DPP4 or DPPIV), also known as adenosine deaminase complexing protein 2 or CD26 (cluster of differentiation 26) is a protein that...

between active TB and other diseases. In 2007, a systematic review of adenosine deaminase by the NHS Health Technology Assessment Programme concluded "There...

with adenosine deaminase deficiency (ADA) tend to have elevated intracellular dATP concentrations because adenosine deaminase normally curbs adenosine levels...

patients with severe combined immunodeficiency (SCID) resulting from an adenosine deaminase deficiency (ADA-SCID). Other treatment options for patients with...

a subfamily of the adenosine deaminase protein family. The encoded protein may act as a growth factor and have adenosine deaminase activity. It may be...

nucleotide A nucleotidase creates adenosine, then adenosine deaminase creates inosine Alternatively, AMP deaminase creates inosinic acid, then a nucleotidase...

deoxyadenosine, it is relatively resistant to breakdown by the enzyme adenosine deaminase, which causes it to accumulate in targeted cells and interfere with...

the enzyme myoadenylate deaminase, freeing an ammonia group. In a catabolic pathway, the purine nucleotide cycle, adenosine monophosphate can be converted...

conversion of adenosine into inosine by adenosine deaminase. AMP + H2O + H+ → IMP + NH3 (catalyzed by AMP deaminase in skeletal muscle) Adenosine + H2O → Inosine...

RNA-editing deaminase-2 (RED2, or ADARB2) is a member of the double-stranded RNA (dsRNA) adenosine deaminase family of RNA-editing enzymes. Adenosine deamination...

AMP deaminase 1 is an enzyme that in humans is encoded by the AMPD1 gene. Adenosine monophosphate deaminase is an enzyme that converts adenosine monophosphate...

structure of metabolic purines, the larger bases incorporated into DNA as adenosine and guanosine. Examples: Azathioprine, Thiopurines, and Fludarabine pyrimidine...

mostly acts on protein-coding substrates. Adenosine deaminase (ADA), an enzyme acting on isolated adenosine GRCh38: Ensembl release 89: ENSG00000197381...

EHNA (erythro-9-(2-hydroxy-3-nonly)adenine) is a potent adenosine deaminase inhibitor, which also acts as a phosphodiesterase inhibitor that selectively...

associated with adenosine deaminase deficiency, which classically manifests in severe combine immunodeficiency (SCID). Accumulated adenosine derivatives,...

type of antimetabolite. It mimics the nucleoside adenosine and thus inhibits the enzyme adenosine deaminase, interfering with the cell's ability to process...