The alpha-2B adrenergic receptor (α2B adrenoceptor), is a G-protein coupled receptor. It is a subtype of the adrenergic receptor family. The human gene...
15 KB (1,754 words) - 20:51, 13 August 2023
The alpha-2C adrenergic receptor (α2C adrenoceptor), also known as ADRA2C, is an alpha-2 adrenergic receptor, and also denotes the human gene encoding...
13 KB (1,541 words) - 00:52, 27 September 2024
The alpha-2A adrenergic receptor (α2A adrenoceptor), also known as ADRA2A, is an α2-adrenergic receptor, and also denotes the human gene encoding it....
12 KB (1,303 words) - 06:39, 19 February 2025
natural diamonds Alpha-2B adrenergic receptor, a type of protein structure 2B (band), a Portuguese band 2B (film), a 2009 science fiction film 2B (Nier: Automata)...
1 KB (189 words) - 21:37, 27 August 2024
Oxymetazoline (category Alpha-1 adrenergic receptor agonists)
activates α1 adrenergic receptors and α2 adrenergic receptors, most notably. One study classified it in the following order: α(2A) > α(1A) ≥ α(2B) > α(1D)...
16 KB (1,475 words) - 03:22, 4 June 2025
Guanfacine (category Alpha-2 adrenergic receptor agonists)
(December 1994). "The novel alpha-2 adrenergic radioligand [3H]-MK912 is alpha-2C selective among human alpha-2A, alpha-2B and alpha-2C adrenoceptors". The...
48 KB (4,414 words) - 10:25, 15 June 2025
Mianserin (category Alpha-1 blockers)
expression, and pharmacological characterization of a human alpha 2B-adrenergic receptor". Molecular Pharmacology. 38 (5): 681–688. doi:10.1016/S0026-895X(25)09495-7...
37 KB (3,163 words) - 23:36, 17 June 2025
Jong, Wilfried W. (2002). "Molecular Evolution of the Mammalian Alpha 2B Adrenergic Receptor". Molecular Biology and Evolution. 19 (12): 2150–2160. doi:10...
66 KB (6,636 words) - 03:59, 23 June 2025
5-Hydroxytryptamine receptor 2B (5-HT2B) also known as serotonin receptor 2B is a protein that in humans is encoded by the HTR2B gene. 5-HT2B is a member...
82 KB (7,913 words) - 17:32, 28 May 2025
Cyclobenzaprine (category Alpha-1 blockers)
norepinephrine reuptake and to block serotonin, adrenergic, histamine, and muscarinic acetylcholine receptors. Chemically, it is very similar to tricyclic...
31 KB (2,421 words) - 23:46, 21 June 2025
Cabergoline (category Alpha-2 blockers)
partial or full agonist at all of these receptors except for the 5-HT7, α1-adrenergic, and α2-adrenergic receptors, where it acts as an antagonist. Cabergoline...
35 KB (3,056 words) - 20:13, 29 May 2025
Lofexidine (category Alpha-2 adrenergic receptor agonists)
is an agonist at the alpha-2A, 2B, and 2C adrenergic receptor subtypes, with the highest activity at the α2A-adrengergic receptor. Ki represents the dissociation...
15 KB (1,407 words) - 21:22, 29 May 2025
Ergotamine (category Alpha-2 adrenergic receptor agonists)
Ergotamine interacts with serotonin, adrenergic, and dopamine receptors. It is an agonist of serotonin receptors including the serotonin 5-HT1 and 5-HT2...
26 KB (1,648 words) - 00:36, 24 June 2025
MDMA (redirect from (+)-N,alpha-dimethyl-3,4-(methylenedioxy)phenethylamine)
interacts with α2-adrenergic receptors, with the sigma σ1 and σ2 receptors, and with the imidazoline I1 receptor. Along with the preceding receptor interactions...
249 KB (23,564 words) - 13:01, 24 June 2025
Phenoxybenzamine (category IARC Group 2B carcinogens)
a permanent covalent bond with adrenergic receptors. Based on known information about the structures of these receptors, it likely involves attack by the...
11 KB (1,033 words) - 14:44, 11 May 2025
Risperidone (category Alpha-1 blockers)
of the sedating effects of risperidone. Alpha α2 adrenergic receptors: Risperidone's action at these receptors may cause greater positive, negative, affective...
56 KB (5,134 words) - 02:20, 16 June 2025
Chlorpromazine (category Alpha-1 blockers)
Also associated with weight gain as a result of blockage of the adrenergic alpha 1 receptor as well as with intraoperative floppy iris syndrome due to its...
69 KB (5,946 words) - 13:35, 17 June 2025
Locomotor activity (section Adrenergic agents)
The α1-adrenergic receptor appears to be facilitatory, whereas the α2-adrenergic receptor appears to be inhibitory, and the β-adrenergic receptors appear...
114 KB (12,382 words) - 04:41, 2 June 2025
Trazodone (category Alpha-1 blockers)
orthostatic hypotension in some people, probably as a consequence of α1-adrenergic receptor blockade. The unmasking of bipolar disorder may occur with trazodone...
120 KB (11,173 words) - 05:25, 17 June 2025
amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing...
10 KB (1,179 words) - 16:27, 20 November 2024
for a second PGI2 receptor in BEAS-2B human airway epithelial cells but this finding has not been collaborated and the putative receptor has not been otherwise...
11 KB (879 words) - 12:45, 14 May 2023
Dihydroergotamine (category Alpha-2 adrenergic receptor agonists)
serotonin receptors and causing vasoconstriction of the intracranial blood vessels, but also interacts centrally with dopamine and adrenergic receptors. It...
17 KB (1,065 words) - 04:23, 10 May 2025
receptor 2 (SSTR2), which belongs to the G-protein coupled receptor family, is a protein which is most highly expressed in the pancreas (both alpha-...
32 KB (4,036 words) - 22:25, 27 May 2025
Amoxapine (category Alpha-1 blockers)
mACh, and GABAA receptors, and no affinity for the β-adrenergic receptors or the allosteric benzodiazepine site on the GABAA receptor. Amoxapine is also...
32 KB (2,715 words) - 20:24, 10 May 2025
Yohimbine (category Alpha-1 blockers)
to fluparoxan at alpha(2)-adrenergic receptors (AR)s, serotonin (5-HT)(1A), 5-HT(1B), 5-HT(1D) and dopamine D(2) and D(3) receptors. Significance for...
44 KB (4,487 words) - 13:19, 21 June 2025
Chlorprothixene (category Alpha-1 blockers)
gain Muscarinic acetylcholine receptors: anticholinergic effects, inhibition of extrapyramidal side effects α1-Adrenergic: hypotension, sedation, anxiolysis...
20 KB (1,284 words) - 20:20, 29 May 2025
decreases the number of cells in the aorta. Minoxidil possesses α2-adrenergic receptor agonist activity, stimulates the peripheral sympathetic nervous system...
48 KB (4,584 words) - 15:46, 20 June 2025
Serotonin (category Non-hallucinogenic 5-HT2A receptor agonists)
serotonin receptors, including the serotonin 5-HT1 (1A, 1B, 1D, 1E, 1F), 5-HT2 (2A, 2B, 2C), 5-HT3, 5-HT4, 5-HT5 (5A, 5B), 5-HT6, and 5-HT7 receptors. Except...
173 KB (18,295 words) - 19:45, 2 June 2025
various nuclear receptors. The structure of the LBD is referred to as an alpha helical sandwich fold in which three anti parallel alpha helices (the "sandwich...
75 KB (6,515 words) - 04:42, 1 May 2025
RAR-related orphan receptor alpha (RORα), also known as NR1F1 (nuclear receptor subfamily 1, group F, member 1) is a nuclear receptor that in humans is...
25 KB (2,662 words) - 16:42, 22 August 2024