C-fos-induced growth factor (FIGF) (or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded...
10 KB (1,256 words) - 05:23, 19 July 2025
bigger Fos family of transcription factors which includes c-Fos, FosB, Fra-1 and Fra-2. It has been mapped to chromosome region 14q21→q31. c-Fos encodes...
26 KB (3,991 words) - 05:29, 10 July 2024
Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia. They...
48 KB (4,885 words) - 00:05, 18 July 2025
proteins belonging to the c-Fos, c-Jun, ATF and JDP families. AP-1 was first discovered as a TPA-activated transcription factor that bound to a cis-regulatory...
42 KB (4,614 words) - 19:07, 4 August 2025
Transcription factor Jun is a protein that in humans is encoded by the JUN gene. c-Jun, in combination with protein c-Fos, forms the AP-1 early response...
46 KB (5,537 words) - 04:52, 15 July 2025
Methamphetamine (section Epigenetic factors)
amphetamine induces a unique transcription factor delta FosB, which plays an essential role in long-term adaptive changes in the brain. Cadet JL, Brannock C, Jayanthi...
170 KB (16,595 words) - 10:50, 5 August 2025
amphetamine induces a unique transcription factor delta FosB, which plays an essential role in long-term adaptive changes in the brain. Cadet JL, Brannock C, Jayanthi...
63 KB (23,111 words) - 23:58, 4 August 2025
amphetamine induces a unique transcription factor delta FosB, which plays an essential role in long-term adaptive changes in the brain. Cadet JL, Brannock C, Jayanthi...
66 KB (22,224 words) - 05:36, 19 July 2025
NF-κB (redirect from Nuclear factor-kappa B)
words, c-Fos repression allows ΔFosB to accumulate within nucleus accumbens medium spiny neurons more rapidly because it is selectively induced in this...
90 KB (9,842 words) - 21:54, 10 July 2025
EGR1 (redirect from Early Growth Response Protein 1)
EGR-1 (Early growth response protein 1) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. EGR-1...
14 KB (1,524 words) - 03:17, 3 August 2025
CREB (category Transcription factors)
1987 as a cAMP-responsive transcription factor regulating the somatostatin gene. Genes whose transcription is regulated by CREB include: c-fos, BDNF, tyrosine...
19 KB (2,243 words) - 23:46, 9 September 2024
synaptic terminals. ... Chronic exposure to amphetamine induces a unique transcription factor delta FosB, which plays an essential role in long-term adaptive...
324 KB (34,743 words) - 00:24, 1 August 2025
HIF1A (redirect from Hypoxia inducible factor 1a)
Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 (HIF-1) that...
65 KB (7,427 words) - 10:18, 18 July 2025
Oncogene (redirect from Proto-oncogene proteins c-fos)
regulator properties include: Growth factors are usually secreted by either specialized or non-specialized cells to induce cell proliferation in themselves...
28 KB (3,143 words) - 03:54, 25 June 2025
2001). "Sp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-induced alpha 2(I) collagen expression in human glomerular mesangial...
30 KB (3,441 words) - 08:44, 5 February 2025
also regulates the transcription of the C-Fos gene. By altering the levels and activities of transcription factors, MAPK leads to altered transcription of...
24 KB (3,066 words) - 14:18, 3 June 2025
that controls motivated behaviors, like defensive behaviors. Analyses of Fos-labeling showed that a series of nuclei in the "behavioral control column"...
50 KB (4,994 words) - 04:59, 2 August 2025
EGR2 (redirect from Early growth response transcription factor)
Early growth response protein 2 is a protein that in humans is encoded by the EGR2 gene. EGR2 (also termed Krox20) is a transcription regulatory factor, containing...
19 KB (2,074 words) - 10:21, 18 July 2025
ATF4 (redirect from Activating transcription factor 4)
T, Curran T (May 1991). "Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity". Proceedings of the...
15 KB (1,773 words) - 03:53, 15 July 2025
Nuclear receptor 4A1 (redirect from Nerve growth factor ib)
NR4A1 has homologous genes in a range of species including neuronal growth factor-induced clone B in rats, Nur77 in mice and TR3 in humans. Along with 16...
21 KB (2,532 words) - 22:04, 15 July 2025
RUNX2 (redirect from Runt-related transcription factor 2)
(January 2002). "Physical interaction of the activator protein-1 factors c-Fos and c-Jun with Cbfa1 for collagenase-3 promoter activation". The Journal...
19 KB (2,246 words) - 09:06, 24 June 2025
Sex-determining region Y protein (redirect from Testis determining factor)
very similar to SRY's. SOX9 leads to the upregulation of fibroblast growth factor 9 (Fgf9), which in turn leads to further upregulation of SOX9. Once...
42 KB (5,211 words) - 15:51, 5 August 2025
c-fos, c-myc and c-jun, genes that were found to be homologous to retroviral oncogenes. Thus IEGs are well known as early regulators of cell growth and...
17 KB (1,965 words) - 00:08, 27 October 2024
Endometriosis (section Risk factors)
Activation of both of the MAP and ERK pathways lead to increased levels of c-Fos and c-Jun, which are proto-oncogenes that are associated with high-grade lesions...
164 KB (16,760 words) - 16:50, 1 August 2025
KIT (gene) (redirect from Stem cell factor receptor)
kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction". Oncogene. 18 (40): 5546–5553...
35 KB (4,121 words) - 06:16, 19 July 2025
USF1 (redirect from Upstream Transcription Factor 1)
transcription factor (AP-1) refers to a complex of dimeric transcription factors composed of c-Jun, c-Fos, or activating transcription factor (ATF) that...
41 KB (4,563 words) - 09:19, 18 July 2025
Mothers against decapentaplegic homolog 2 (category Transcription factors)
Transforming Growth Factor β Signals". Mol. Cell. Biol. 19 (1): 424–30. doi:10.1128/MCB.19.1.424. ISSN 0270-7306. PMC 83900. PMID 9858566. Liu F, Pouponnot C, Massagué...
16 KB (1,925 words) - 17:29, 17 July 2025
melanoma growth stimulating activity, alpha (MGSA-α). CXCL1 was first cloned from a cDNA library of genes induced by platelet-derived growth factor (PDGF)...
14 KB (1,728 words) - 16:03, 28 October 2024
Puppy nutrition (redirect from Growth diets for puppies)
FOS are fermented by beneficial bacteria such as bifidobacteria promoting their growth, while most pathogenic bacterial strains such as E. coli, C. perfringens...
29 KB (3,973 words) - 20:07, 26 May 2025