• Thumbnail for C-fos-induced growth factor
    C-fos-induced growth factor (FIGF) (or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded...
    10 KB (1,256 words) - 05:23, 19 July 2025
  • Thumbnail for Protein c-Fos
    bigger Fos family of transcription factors which includes c-Fos, FosB, Fra-1 and Fra-2. It has been mapped to chromosome region 14q21→q31. c-Fos encodes...
    26 KB (3,991 words) - 05:29, 10 July 2024
  • Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia. They...
    48 KB (4,885 words) - 00:05, 18 July 2025
  • Thumbnail for AP-1 transcription factor
    proteins belonging to the c-Fos, c-Jun, ATF and JDP families. AP-1 was first discovered as a TPA-activated transcription factor that bound to a cis-regulatory...
    42 KB (4,614 words) - 19:07, 4 August 2025
  • Thumbnail for Transcription factor Jun
    Transcription factor Jun is a protein that in humans is encoded by the JUN gene. c-Jun, in combination with protein c-Fos, forms the AP-1 early response...
    46 KB (5,537 words) - 04:52, 15 July 2025
  • Thumbnail for Methamphetamine
    amphetamine induces a unique transcription factor delta FosB, which plays an essential role in long-term adaptive changes in the brain. Cadet JL, Brannock C, Jayanthi...
    170 KB (16,595 words) - 10:50, 5 August 2025
  • Thumbnail for Adderall
    amphetamine induces a unique transcription factor delta FosB, which plays an essential role in long-term adaptive changes in the brain. Cadet JL, Brannock C, Jayanthi...
    63 KB (23,111 words) - 23:58, 4 August 2025
  • Thumbnail for FOSB
    FOSB (redirect from FosB)
    proteins of the JUN family (e.g., c-Jun, JunD), thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as...
    57 KB (7,191 words) - 16:36, 17 July 2025
  • Thumbnail for Dextroamphetamine
    amphetamine induces a unique transcription factor delta FosB, which plays an essential role in long-term adaptive changes in the brain. Cadet JL, Brannock C, Jayanthi...
    66 KB (22,224 words) - 05:36, 19 July 2025
  • Thumbnail for NF-κB
    words, c-Fos repression allows ΔFosB to accumulate within nucleus accumbens medium spiny neurons more rapidly because it is selectively induced in this...
    90 KB (9,842 words) - 21:54, 10 July 2025
  • Thumbnail for EGR1
    EGR-1 (Early growth response protein 1) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. EGR-1...
    14 KB (1,524 words) - 03:17, 3 August 2025
  • Thumbnail for CREB
    CREB (category Transcription factors)
    1987 as a cAMP-responsive transcription factor regulating the somatostatin gene. Genes whose transcription is regulated by CREB include: c-fos, BDNF, tyrosine...
    19 KB (2,243 words) - 23:46, 9 September 2024
  • Thumbnail for Amphetamine
    synaptic terminals. ... Chronic exposure to amphetamine induces a unique transcription factor delta FosB, which plays an essential role in long-term adaptive...
    324 KB (34,743 words) - 00:24, 1 August 2025
  • Thumbnail for HIF1A
    Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 (HIF-1) that...
    65 KB (7,427 words) - 10:18, 18 July 2025
  • Thumbnail for Oncogene
    regulator properties include: Growth factors are usually secreted by either specialized or non-specialized cells to induce cell proliferation in themselves...
    28 KB (3,143 words) - 03:54, 25 June 2025
  • Thumbnail for Transcription factor Sp1
    2001). "Sp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-induced alpha 2(I) collagen expression in human glomerular mesangial...
    30 KB (3,441 words) - 08:44, 5 February 2025
  • also regulates the transcription of the C-Fos gene. By altering the levels and activities of transcription factors, MAPK leads to altered transcription of...
    24 KB (3,066 words) - 14:18, 3 June 2025
  • Thumbnail for Hypothalamus
    that controls motivated behaviors, like defensive behaviors. Analyses of Fos-labeling showed that a series of nuclei in the "behavioral control column"...
    50 KB (4,994 words) - 04:59, 2 August 2025
  • Thumbnail for EGR2
    Early growth response protein 2 is a protein that in humans is encoded by the EGR2 gene. EGR2 (also termed Krox20) is a transcription regulatory factor, containing...
    19 KB (2,074 words) - 10:21, 18 July 2025
  • Thumbnail for ATF4
    T, Curran T (May 1991). "Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity". Proceedings of the...
    15 KB (1,773 words) - 03:53, 15 July 2025
  • Thumbnail for Nuclear receptor 4A1
    NR4A1 has homologous genes in a range of species including neuronal growth factor-induced clone B in rats, Nur77 in mice and TR3 in humans. Along with 16...
    21 KB (2,532 words) - 22:04, 15 July 2025
  • Thumbnail for RUNX2
    (January 2002). "Physical interaction of the activator protein-1 factors c-Fos and c-Jun with Cbfa1 for collagenase-3 promoter activation". The Journal...
    19 KB (2,246 words) - 09:06, 24 June 2025
  • Thumbnail for Sex-determining region Y protein
    very similar to SRY's. SOX9 leads to the upregulation of fibroblast growth factor 9 (Fgf9), which in turn leads to further upregulation of SOX9. Once...
    42 KB (5,211 words) - 15:51, 5 August 2025
  • c-fos, c-myc and c-jun, genes that were found to be homologous to retroviral oncogenes. Thus IEGs are well known as early regulators of cell growth and...
    17 KB (1,965 words) - 00:08, 27 October 2024
  • Thumbnail for Endometriosis
    Activation of both of the MAP and ERK pathways lead to increased levels of c-Fos and c-Jun, which are proto-oncogenes that are associated with high-grade lesions...
    164 KB (16,760 words) - 16:50, 1 August 2025
  • Thumbnail for KIT (gene)
    kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction". Oncogene. 18 (40): 5546–5553...
    35 KB (4,121 words) - 06:16, 19 July 2025
  • Thumbnail for USF1
    transcription factor (AP-1) refers to a complex of dimeric transcription factors composed of c-Jun, c-Fos, or activating transcription factor (ATF) that...
    41 KB (4,563 words) - 09:19, 18 July 2025
  • Thumbnail for Mothers against decapentaplegic homolog 2
    Mothers against decapentaplegic homolog 2 (category Transcription factors)
    Transforming Growth Factor β Signals". Mol. Cell. Biol. 19 (1): 424–30. doi:10.1128/MCB.19.1.424. ISSN 0270-7306. PMC 83900. PMID 9858566. Liu F, Pouponnot C, Massagué...
    16 KB (1,925 words) - 17:29, 17 July 2025
  • Thumbnail for CXCL1
    melanoma growth stimulating activity, alpha (MGSA-α). CXCL1 was first cloned from a cDNA library of genes induced by platelet-derived growth factor (PDGF)...
    14 KB (1,728 words) - 16:03, 28 October 2024
  • Thumbnail for Puppy nutrition
    FOS are fermented by beneficial bacteria such as bifidobacteria promoting their growth, while most pathogenic bacterial strains such as E. coli, C. perfringens...
    29 KB (3,973 words) - 20:07, 26 May 2025