• Thumbnail for Muscle contraction
    mechanical response is contraction. Excitationcontraction coupling can be dysregulated in many diseases. Though excitationcontraction coupling has been known...
    62 KB (7,395 words) - 13:08, 25 May 2025
  • Cardiac excitation-contraction coupling (Cardiac EC coupling) describes the series of events, from the production of an electrical impulse (action potential)...
    13 KB (1,426 words) - 06:43, 2 June 2025
  • Thumbnail for Cardiac muscle
    myofilaments to slide past each other in a process called excitation-contraction coupling. Diseases of the heart muscle known as cardiomyopathies are...
    42 KB (5,070 words) - 15:47, 26 May 2025
  • Thumbnail for Cardiac action potential
    potential (see phase 2, below) and is a fundamental step in cardiac excitation-contraction coupling. There are important physiological differences between...
    46 KB (5,450 words) - 17:12, 26 May 2025
  • Thumbnail for T-tubule
    the chain from electrical excitation of a cell to its subsequent contraction (excitation-contraction coupling). When contraction of a muscle is needed, stimulation...
    25 KB (3,239 words) - 22:26, 16 March 2025
  • incomplete looping of the cardiac tube. In an adult heart, myocardium contraction occurs via excitation-contraction coupling whereby cellular depolarisation...
    37 KB (4,546 words) - 18:45, 27 May 2025
  • resulting influx of Ca2+ ions lead to the initiation of excitation-contraction coupling and thus contraction of the myocyte.[citation needed] Tubuloglomerular...
    9 KB (1,119 words) - 07:47, 17 October 2024
  • cells excitation-contraction coupling maintenance of low Ca2+ concentration in the mitochondria The exchanger is also implicated in the cardiac electrical...
    20 KB (2,223 words) - 06:03, 28 May 2025
  • Thumbnail for Skeletal muscle
    as a triad and is predominantly where excitationcontraction coupling takes place. Excitationcontraction coupling occurs when depolarization of skeletal...
    119 KB (13,832 words) - 17:30, 27 May 2025
  • 1152/advances.2003.27.4.201. PMID 14627618. Bers, D.M. (2002). "Cardiac excitation-contraction coupling". Nature. 415 (6868): 198–205. Bibcode:2002Natur.415..198B...
    18 KB (2,319 words) - 13:29, 23 July 2024
  • calcium release. Instead, CICR is thought to be crucial for excitation-contraction coupling in cardiac muscle. It is now obvious that CICR is a widely occurring...
    4 KB (423 words) - 09:37, 2 November 2022
  • Diad (category Cardiac anatomy)
    will trigger a united muscular contraction. This process is known as excitation-contraction coupling. This contraction pushes blood inside the heart and...
    9 KB (1,199 words) - 15:08, 4 January 2024
  • Thumbnail for Calsequestrin
    associated with cardiac arrhythmia and sudden death. CASQ2 is thought to have a role in regulating cardiac excitation-contraction coupling and calcium-induced...
    7 KB (704 words) - 22:36, 23 May 2025
  • Thumbnail for Smooth muscle
    skeletal muscle and cardiac muscle in terms of structure, function, regulation of contraction, and excitation-contraction coupling. However, smooth muscle...
    37 KB (4,737 words) - 17:18, 22 January 2025
  • Thumbnail for Sarcoplasmic reticulum
    detail below and are fundamental for the process of excitation-contraction coupling in skeletal, cardiac and smooth muscle. The SR contains ion channel pumps...
    13 KB (1,810 words) - 03:02, 24 March 2025
  • Thumbnail for Systole
    this electrical flux causes coordinated depolarisation and excitation-contraction coupling from the apex of the heart up to the roots of the great vessels...
    20 KB (2,459 words) - 18:32, 14 September 2024
  • Thumbnail for Terminal cisternae
    linked to the terminal cisternae which facilitate excitation-contraction coupling. When excitation of the membrane arrives at the T-tubule nearest the...
    3 KB (345 words) - 22:09, 23 May 2025
  • current pulses applied during cardiac action potentials. II. Hypotheses: calcium movements, excitation-contraction coupling and inotropic effects". Circ...
    42 KB (4,758 words) - 05:05, 26 May 2025
  • Thumbnail for Catecholaminergic polymorphic ventricular tachycardia
    93. PMID 22733215. S2CID 24883043. Bers, DM (2001). Excitation-contraction coupling and cardiac contractile force (2nd ed.). Dordrecht: Kluwer Academic...
    42 KB (4,772 words) - 18:48, 28 May 2025
  • Thumbnail for Triad (anatomy)
    muscle fiber. Triads form the anatomical basis of excitation-contraction coupling, whereby a stimulus excites the muscle and causes it to contract. A stimulus...
    2 KB (263 words) - 22:03, 10 January 2024
  • Thumbnail for Omecamtiv mecarbil
    doi:10.1093/eurheartj/sui009. Bers DM (January 2002). "Cardiac excitation-contraction coupling". Nature. 415 (6868): 198–205. Bibcode:2002Natur.415..198B...
    18 KB (1,539 words) - 10:56, 16 March 2025
  • Pulseless electrical activity (category Cardiac arrhythmia)
    mechanical contraction of the heart (known as electromechanical coupling). In PEA, there is electrical activity but insufficient cardiac output to generate...
    10 KB (970 words) - 06:48, 27 March 2025
  • journal requires |journal= (help) M., Bers, D. (2001). Excitation-contraction coupling and cardiac contractile force (2nd ed.). Dordrecht: Kluwer Academic...
    5 KB (616 words) - 03:08, 2 December 2024
  • Voltage-dependent calcium channels are responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle and for regulating aldosterone and cortisol...
    31 KB (3,456 words) - 02:24, 25 May 2025
  • Thumbnail for Antiporter
    these proteins to carry out functions such as cardiac muscle relaxation, excitation-contraction coupling, and photoreceptor activity. They also maintain...
    60 KB (7,840 words) - 00:16, 11 February 2025
  • Jayasinghe, I. (2010). Resolving the structural basis of cardiac excitation-contraction coupling (Doctoral thesis). ResearchSpace@Auckland, University of...
    7 KB (576 words) - 02:06, 25 September 2024
  • Thumbnail for Ryanodine receptor
    primarily expressed in skeletal muscle It is essential for excitation-contraction coupling RyR2 is primarily expressed in myocardium (heart muscle) the...
    25 KB (2,675 words) - 20:15, 23 May 2025
  • Thumbnail for GCaMP
    excitation light. Moreover, red fluorescent indicators allow for concurrent use of optogenetics, which is difficult with GCaMP because the excitation...
    28 KB (3,066 words) - 21:20, 28 February 2025
  • dihydropyridine-sensitive L-type channels responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle and for hormone secretion in endocrine...
    28 KB (3,041 words) - 03:48, 25 May 2025
  • membranes and macromolecular complexes responsible for excitation-contraction coupling in cardiac and skeletal muscles Her structural work can be divided...
    10 KB (1,098 words) - 05:31, 2 June 2025