• The Claisen condensation is a carbon–carbon bond forming reaction that occurs between two esters or one ester and another carbonyl compound in the presence...
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  • In organic chemistry, the Claisen–Schmidt condensation is the reaction between an aldehyde or ketone having an α-hydrogen with an aromatic carbonyl compound...
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  • as the Claisen condensation and the Dieckman condensation (intramolecular Claisen condensation), which form alcohols as by-products. Condensation reactions...
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  • Thumbnail for Dieckmann condensation
    (1869–1925). The equivalent intermolecular reaction is the Claisen condensation. Dieckmann condensations are highly effective routes to 5-, 6-, and 7-member...
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  • Thumbnail for Aldol condensation
    Claisen-Schmidt condensation between an aldehyde or ketone having an α-hydrogen with an aromatic carbonyl compound lacking an α-hydrogen. A Claisen condensation...
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  • Thumbnail for Ester
    which can further react, e.g., the Claisen condensation and its intramolecular equivalent, the Dieckmann condensation. This conversion is exploited in the...
    41 KB (4,351 words) - 00:19, 1 May 2024
  • Thumbnail for Stobbe condensation
    Stobbe condensation is also illustrated by the synthesis of the drug tametraline. Aldol condensation Polyketide synthase Dieckmann condensation Claisen condensation...
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  • δ-unsaturated carbonyl Claisen condensation, a reaction between esters and carbonyl compounds in the presence of a strong base Ireland–Claisen rearrangement,...
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  • Crossed Claisen condensations, in which the enolate and nucleophile are different esters, are also possible. An intramolecular Claisen condensation is called...
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  • Thumbnail for Rainer Ludwig Claisen
    Claisen (German pronunciation: [ˈʁaɪnɐ ˈklaɪzn̩]; 14 January 1851 – 5 January 1930) was a German chemist best known for his work with condensations of...
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  • Thumbnail for Darzens reaction
    The Darzens reaction (also known as the Darzens condensation or glycidic ester condensation) is the chemical reaction of a ketone or aldehyde with an...
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  • elimination Ciamician–Dennstedt rearrangement Claisen condensation Claisen rearrangement Claisen–Schmidt condensation Clemmensen reduction Collins reagent Combes...
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  • Thumbnail for Cyclopentyl methyl ether
    Reaction etc. Reactions using Organometallic reagents or basic agents: Claisen condensation, formation of enolates or Grignard reaction. Reduction and oxidation...
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  • the current AT domain. The ACP-bound elongation group reacts in a Claisen condensation with the KS-bound polyketide chain under CO2 evolution, leaving a...
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  • Thumbnail for Thiolase
    catalyse the carbon–carbon-bond formation via a thioester-dependent Claisen condensation reaction mechanism. Thiolases are a family of evolutionarily related...
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  • inhibiting the reaction. Benzoin condensation Bouveault–Blanc reduction Claisen condensation Dieckmann condensation Bouveault, L.; Locquin, R. (1905)...
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  • Thumbnail for Cocaine
    through a Claisen condensation. This produces a racemic mixture of the 2-substituted pyrrolidine, with the retention of the thioester from the Claisen condensation...
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  • atom. Enols are commonly used in condensation reactions, including the Claisen condensation and the aldol condensation reactions.[citation needed] Examples...
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  • Thumbnail for Dibenzylideneacetone
    often performed in organic chemistry classes, and is called Claisen-Schmidt condensation. Prolonged exposure to sunlight initiates [2+2] cycloadditions...
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  • acceptors. Unlike 1,3-dicarbonyls, which are easily accessed through the Claisen condensation, or 1,5-dicarbonyls, which are commonly made using a Michael reaction...
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  • Thumbnail for Ethyl acetate
    unreactive toward ethanol: CH3CO2C2H5 + NaOH → C2H5OH + CH3CO2Na In the Claisen condensation, anhydrous ethyl acetate and strong bases react to give ethyl acetoacetate:...
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  • Thumbnail for Keto acid
    second carbon from the carboxylic acid. They generally form by the Claisen condensation. The presence of the keto group at the beta position allows them...
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  • methoxy group): The key step in the assembly of quinotoxine is a Claisen condensation: 1944: Robert Burns Woodward and W. E. Doering report the synthesis...
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  • Thumbnail for HMG-CoA
    Mevalonate synthesis begins with the beta-ketothiolase-catalyzed Claisen condensation of two molecules of acetyl-CoA to produce acetoacetyl CoA. The following...
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  • The fatty acids are synthesized by a series of decarboxylative Claisen condensation reactions from acetyl-CoA and malonyl-CoA. Following each round of...
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  • Thumbnail for Phenobarbital
    phenylacetic acid ethyl ester. Subsequently, this ester undergoes cross Claisen condensation using diethyl oxalate, giving diethyl ester of phenyloxobutandioic...
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  • Thumbnail for Biosynthesis of cocaine
    through a Claisen condensation. This produces a racemic mixture of the 2-substituted pyrrolidine, with the retention of the thioester from the Claisen condensation...
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  • Thumbnail for Knorr pyrrole synthesis
    2-oximinoacetoacetate and 2-methyl-3-oxobutanal, in turn made by the Claisen condensation of 2-butanone with ethyl formate. George Kleinspehn reported that...
    14 KB (1,546 words) - 23:40, 21 March 2024
  • domain, followed by transfer to malonyl-ACP via decarboxylative Claisen condensation. This fragment is then able to react with the masked carbanion formed...
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  • Thumbnail for Avobenzone
    4-methoxyacetophenone in toluene in the presence of sodium amide via Claisen condensation. According to a recent patent application, yields of up to 95% are...
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