In genomics, DNA–DNA hybridization is a molecular biology technique that measures the degree of genetic similarity between DNA sequences. It is used to...
14 KB (1,560 words) - 06:47, 17 May 2025
Tianqi; Garg, Sudhanshu; Reif, John (2018-01-25). "Localized DNA Hybridization Chain Reactions on DNA Origami". ACS Nano. 12 (2): 1146–1155. doi:10.1021/acsnano...
43 KB (4,922 words) - 19:27, 26 April 2025
to hybridize with RNA spike-ins. The degree of hybridization between the spike-ins and the control probes is used to normalize the hybridization measurements...
54 KB (5,405 words) - 16:14, 8 June 2025
Fluorescence In Situ Hybridization (FISH) technique was developed in the 1980s. The basic idea is to use a nucleic acid probe to hybridize nuclear DNA from either...
25 KB (3,236 words) - 02:14, 10 June 2025
complementary DNA (cDNA) is DNA that was reverse transcribed (via reverse transcriptase) from an RNA (e.g., messenger RNA or microRNA). cDNA exists in both...
19 KB (2,275 words) - 04:33, 26 May 2025
include RNA:DNA hybridization leading to the discovery that considerably less than 10% of the human genome was complementary to mRNA and this DNA was in the...
36 KB (3,906 words) - 18:04, 12 June 2025
extremely high hybridization stringency and ligation specificity. There are at least three different units used to measure the activity of DNA ligase: Weiss...
23 KB (2,831 words) - 11:16, 18 June 2025
Methylation Assay measures locus-specific DNA methylation using array hybridization. Bisulfite-treated DNA is hybridized to probes on "BeadChips." Single-base...
117 KB (13,348 words) - 15:37, 4 June 2025
DNA can hybridize with the more common B-DNA. These A-B intermediate forms adopt the sugar pucker properties and/or the base conformation of both DNA...
12 KB (1,229 words) - 01:36, 24 May 2025
pool of DNA whose sequence is to be determined is fluorescently labeled and hybridized to an array containing known sequences. Strong hybridization signals...
136 KB (15,505 words) - 05:38, 2 June 2025
A DNA sequencer is a scientific instrument used to automate the DNA sequencing process. Given a sample of DNA, a DNA sequencer is used to determine the...
37 KB (3,850 words) - 23:38, 23 March 2024
Primer (molecular biology) (redirect from DNA primer)
need to be chosen to uniquely select for a region of DNA, avoiding the possibility of hybridization to a similar sequence nearby. A commonly used method...
16 KB (1,943 words) - 01:19, 19 June 2025
Southern blot (redirect from Southern hybridization)
permanently attach the transferred DNA to the membrane. Hybridization: After that, a hybridization probe—a single DNA fragment with a particular sequence...
17 KB (2,313 words) - 21:59, 23 May 2025
molecules to anneal or “hybridize” to each other. DNA replication and transcription of DNA into RNA both rely upon nucleotide hybridization, as do molecular...
5 KB (564 words) - 11:50, 26 August 2024
Recombinant DNA (rDNA) molecules are DNA molecules formed by laboratory methods of genetic recombination (such as molecular cloning) that bring together...
34 KB (3,852 words) - 06:09, 15 December 2024
sites in a DNA sample generates variable lengths of DNA fragments, which are separated using gel electrophoresis. They are then hybridized with DNA probes...
12 KB (1,498 words) - 21:43, 24 May 2025
S2CID 2064216. DNA machines: Yan H, Zhang X, Shen Z, Seeman NC (January 2002). "A robust DNA mechanical device controlled by hybridization topology". Nature...
84 KB (9,653 words) - 21:36, 14 June 2025
on each end allowing for hybridization. Once the target gene has hybridized to the vector DNA, they can be joined using a DNA ligase. An alternative strategy...
14 KB (1,696 words) - 18:55, 22 May 2025
using DNA, allowing for last-in, first-out (LIFO) data recording and retrieval. Their approach used hybridization and strand displacement to record DNA signals...
32 KB (3,775 words) - 04:12, 2 June 2025
Deoxyribonucleic acid (/diːˈɒksɪˌraɪboʊnjuːˌkliːɪk, -ˌkleɪ-/ ; DNA) is a polymer composed of two polynucleotide chains that coil around each other to...
167 KB (17,918 words) - 13:14, 17 June 2025
In molecular biology, a hybridization probe (HP) is a fragment of DNA or RNA, usually 15–10000 nucleotides long, which can be radioactively or fluorescently...
9 KB (1,007 words) - 22:42, 4 January 2025
Molecular cloning (redirect from Recombinant DNA technology)
experimental methods in molecular biology that are used to assemble recombinant DNA molecules and to direct their replication within host organisms. The use...
32 KB (4,017 words) - 04:13, 12 April 2025
genomic hybridization (CGH) is a molecular cytogenetic method for analysing copy number variations (CNVs) relative to ploidy level in the DNA of a test...
40 KB (5,286 words) - 05:27, 17 June 2024
microfluidic flow to increase DNA hybridization efficiency, decreasing expensive FISH probe consumption and reduce the hybridization time. MA-FISH is applied...
39 KB (4,596 words) - 20:24, 12 May 2025
Molecular phylogenetics (redirect from DNA taxonomy)
between the genotypes of individuals by DNA–DNA hybridization. The advantage claimed for using hybridization rather than gene sequencing was that it was based...
18 KB (2,195 words) - 16:28, 25 May 2025
Transcription (biology) (redirect from DNA transcription)
is the process of copying a segment of DNA into RNA for the purpose of gene expression. Some segments of DNA are transcribed into RNA molecules that...
58 KB (6,898 words) - 13:44, 24 May 2025
"Chromosomal localization of human O6-methylguanine-DNA methyltransferase (MGMT) gene by in situ hybridization". Mutagenesis. 7 (1): 83–5. doi:10.1093/mutage/7...
32 KB (3,857 words) - 22:04, 28 July 2024
Helicase (redirect from DNA helicase)
RNA helicases and 31 DNA helicases. Many cellular processes, such as DNA replication, transcription, translation, recombination, DNA repair and ribosome...
55 KB (6,744 words) - 07:46, 15 March 2025
Eukaryotic DNA replication is a conserved mechanism that restricts DNA replication to once per cell cycle. Eukaryotic DNA replication of chromosomal DNA is central...
121 KB (14,916 words) - 04:06, 3 January 2025
Nucleic acid thermodynamics (redirect from Hybrid DNA)
e., the dsDNA molecule exists as two independent strands), is referred to as having been denatured by the high temperature. Hybridization is the process...
24 KB (2,923 words) - 02:42, 25 January 2025