• Thumbnail for DNA binding site
    DNA binding sites are a type of binding site found in DNA where other molecules may bind. DNA binding sites are distinct from other binding sites in that...
    21 KB (2,176 words) - 21:02, 17 August 2024
  • Thumbnail for DNA-binding protein
    DNA-binding proteins are proteins that have DNA-binding domains and thus have a specific or general affinity for single- or double-stranded DNA. Sequence-specific...
    22 KB (2,637 words) - 06:01, 3 April 2025
  • single-stranded DNA. A DBD can recognize a specific DNA sequence (a recognition sequence) or have a general affinity to DNA. Some DNA-binding domains may...
    20 KB (2,348 words) - 06:00, 23 April 2025
  • Thumbnail for Transcription (biology)
    about half of EGR1 binding sites are located in promoters and half in enhancers. The binding of EGR1 to its target DNA binding site is insensitive to cytosine...
    58 KB (6,898 words) - 21:17, 23 March 2025
  • Thumbnail for Transcription factor
    sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific...
    75 KB (8,348 words) - 20:03, 18 March 2025
  • Thumbnail for TAR DNA-binding protein 43
    Transactive response DNA binding protein 43 kDa (TAR DNA-binding protein 43 or TDP-43) is a protein that in humans is encoded by the TARDBP gene. TDP-43...
    41 KB (4,646 words) - 22:19, 12 October 2024
  • Thumbnail for Single-stranded binding protein
    two-subunit DNA polymerase, a Helicase-primase complex and a single-stranded DNA-binding protein. The human herpesvirus 1 (HHV-1) single-strand DNA-binding protein...
    10 KB (1,016 words) - 04:21, 25 August 2024
  • is an enzyme that cleaves DNA into fragments at or near specific recognition sites within molecules known as restriction sites. Restriction enzymes are...
    55 KB (5,856 words) - 08:25, 13 May 2025
  • Thumbnail for RNA polymerase
    mediator complex must be attached to a DNA binding site called a promoter region before RNAP can initiate the DNA unwinding at that position. RNAP not only...
    43 KB (5,109 words) - 01:03, 12 May 2025
  • noncovalent binding of DnaG to the DnaB helicase protein. The zinc-binding domain, the domain responsible for recognizing sequence specific DNA binding sites, is...
    20 KB (2,544 words) - 14:58, 5 November 2024
  • properties of DNA provide important constraints on the binding sites formed on surfaces of DNA-binding proteins. Characteristics of such binding sites may be...
    6 KB (735 words) - 16:08, 8 August 2023
  • DNA adenine methyltransferase identification, often abbreviated DamID, is a molecular biology protocol used to map the binding sites of DNA- and chromatin-binding...
    18 KB (2,212 words) - 14:17, 26 April 2024
  • Thumbnail for Zinc finger
    to the CpG site. It is used in mammals for antiviral defense. Various protein engineering techniques can be used to alter the DNA-binding specificity...
    42 KB (4,882 words) - 12:55, 7 February 2025
  • Thumbnail for DnaA
    DnaA binding to 9-mer (9-bp) repeats upstream of oriC. Binding of DnaA leads to strand separation at the 13-mer repeats. This binding causes the DNA to...
    34 KB (4,283 words) - 16:08, 15 December 2024
  • Thumbnail for Origin of replication
    conserved DNA repeats that are specifically recognized by DnaA (called DnaA-boxes), an AT-rich DNA unwinding element (DUE), and binding sites for proteins...
    113 KB (12,563 words) - 03:12, 16 December 2024
  • ChIP sequencing (category DNA)
    interactions with DNA. ChIP-seq combines chromatin immunoprecipitation (ChIP) with massively parallel DNA sequencing to identify the binding sites of DNA-associated...
    27 KB (3,353 words) - 03:17, 31 July 2024
  • Thumbnail for Promoter (genetics)
    gene. Promoters contain specific DNA sequences such as response elements that provide a secure initial binding site for RNA polymerase and for proteins...
    55 KB (6,390 words) - 04:34, 11 March 2025
  • A ribosome binding site, or ribosomal binding site (RBS), is a sequence of nucleotides upstream of the start codon of an mRNA transcript that is responsible...
    12 KB (1,334 words) - 23:00, 16 April 2025
  • to occur. Most activators are DNA-binding proteins that bind to enhancers or promoter-proximal elements. The DNA site bound by the activator is referred...
    17 KB (1,959 words) - 02:34, 31 December 2023
  • Thumbnail for DNA
    articles) DNA binding site prediction on protein DNA the Double Helix Game From the official Nobel Prize web site DNA under electron microscope Dolan DNA Learning...
    167 KB (17,917 words) - 14:25, 15 April 2025
  • target site that contain transcription factor binding sites. The original definition presented cis-regulatory modules as enhancers of cis-acting DNA, which...
    30 KB (3,472 words) - 02:52, 18 February 2024
  • CUT&RUN sequencing (category DNA sequencing)
    DNA sequencing to identify the binding sites of DNA-associated proteins. It can be used to map global DNA binding sites precisely for any protein of interest...
    16 KB (2,049 words) - 21:14, 24 October 2024
  • Thumbnail for DNA-binding protein from starved cells
    DNA-binding proteins from starved cells (Dps) are bacterial proteins that belong to the ferritin superfamily and are characterized by strong similarities...
    13 KB (1,596 words) - 15:13, 1 October 2024
  • Thumbnail for Genome editing
    Genome editing (redirect from DNA editing)
    recognition of target genomic loci and binding of effector DNA-binding domain (DBD), double-strand breaks (DSBs) in target DNA by the restriction endonucleases...
    78 KB (9,365 words) - 16:31, 10 May 2025
  • Thumbnail for Repressor
    Repressor (category DNA-binding proteins)
    a DNA- or RNA-binding protein that inhibits the expression of one or more genes by binding to the operator or associated silencers. A DNA-binding repressor...
    13 KB (1,503 words) - 19:58, 1 January 2024
  • Thumbnail for Sequence logo
    create sequence logos, related DNA, RNA or protein sequences, or DNA sequences that have common conserved binding sites, are aligned so that the most conserved...
    8 KB (994 words) - 20:47, 29 June 2024
  • about half of EGR1 binding sites are located in promoters and half in enhancers. The binding of EGR1 to its target DNA binding site is insensitive to cytosine...
    37 KB (4,283 words) - 02:29, 20 May 2025
  • Thumbnail for DNA adenine methylase
    identify protein binding sites. When DNA polymerase makes an error resulting in a mismatched base-pair or a small insertion or deletion during DNA synthesis...
    16 KB (1,844 words) - 03:29, 2 December 2024
  • Thumbnail for Lac repressor
    The lac repressor (LacI) is a DNA-binding protein that inhibits the expression of genes coding for proteins involved in the metabolism of lactose in bacteria...
    15 KB (1,690 words) - 06:19, 17 April 2025
  • Thumbnail for Primer binding site
    primer binding site is a region of a nucleotide sequence where an RNA or DNA single-stranded primer binds to start replication. The primer binding site is...
    6 KB (633 words) - 18:32, 6 April 2024