DNA fragmentation is the separation or breaking of DNA strands into pieces. It can be done intentionally by laboratory personnel or by cells, or can occur...
12 KB (1,498 words) - 22:54, 31 March 2025
Apoptotic DNA fragmentation is a key feature of apoptosis, a type of programmed cell death. Apoptosis is characterized by the activation of endogenous...
20 KB (2,230 words) - 02:48, 23 November 2024
Asthenozoospermia (section DNA fragmentation)
were found to have high levels of DNA fragmentation. As reviewed by Wright et al., high levels of DNA fragmentation have been shown to be a robust indicator...
5 KB (520 words) - 19:09, 27 November 2023
Paternal age effect (section DNA fragmentation)
chromosome integrity and DNA fragmentation. Advanced paternal age was shown to be associated with a significant increase in DNA fragmentation in a recent systematic...
53 KB (5,524 words) - 19:36, 10 February 2025
death pathways. It is an important stage that involves fragmentation and condensation of damaged DNA/chromatin. Without it, the apoptotic or necrotic cell...
16 KB (1,780 words) - 14:07, 14 December 2024
sometimes cause fragmentation that results in irregularities such as red blood cell fragmentation and sperm cell DNA fragmentation. DNA cloning can be...
12 KB (1,724 words) - 12:55, 26 January 2025
(TUNEL) is a method for detecting DNA fragmentation by labeling the 3′- hydroxyl termini in the double-strand DNA breaks generated during apoptosis....
6 KB (756 words) - 17:02, 28 November 2024
Sperm Chromatin Structure Assay (category DNA)
extent of DNA fragmentation. First described by Evenson in 1980, the assay is a flow cytometric test that detects the vulnerability of sperm DNA to acid-induced...
31 KB (3,564 words) - 21:31, 14 December 2024
changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, DNA fragmentation, and mRNA decay. The average adult human loses...
94 KB (10,857 words) - 08:54, 14 April 2025
indicative of apoptotic DNA fragmentation, suggesting that apoptosis may be the primary method of ctDNA release. The fragmentation of cfDNA is altered in the...
49 KB (5,861 words) - 13:40, 10 March 2025
Caspase-activated DNase (CAD) or DNA fragmentation factor subunit beta is a protein that in humans is encoded by the DFFB gene. It breaks up the DNA during apoptosis...
25 KB (3,047 words) - 19:09, 24 June 2024
Spermatid (section DNA repair)
joining repair pathway. If DNA strand breaks persist in mature sperm, the result can be increased sperm DNA fragmentation which is associated with impaired...
6 KB (594 words) - 02:05, 27 October 2024
Restriction digest (redirect from DNA digestion)
used in molecular biology to prepare DNA for analysis or other processing. It is sometimes termed DNA fragmentation, though this term is used for other...
6 KB (784 words) - 02:16, 13 March 2024
DNA laddering is a feature that can be observed when DNA fragments, resulting from Apoptosis DNA fragmentation are visualized after separation by gel electrophoresis...
6 KB (678 words) - 19:36, 28 November 2024
Spermatozoon (section DNA damage and repair)
spermatozoa often occurs in association with increased DNA damage. DNA fragmentation and increased in situ DNA susceptibility to denaturation, the features similar...
36 KB (4,219 words) - 15:45, 4 April 2025
Chromosome (redirect from DNA packaging)
Orvieto R, Piomboni P (November 2015). "Chromosomal aneuploidies and DNA fragmentation of human spermatozoa from patients exposed to perfluorinated compounds"...
64 KB (6,603 words) - 01:38, 2 May 2025
Comet assay (section Sperm DNA fragmentation)
A comet assay can determine the degree of DNA fragmentation in sperm cells. The degree of DNA fragmentation has been associated with outcomes of in vitro...
20 KB (2,515 words) - 10:24, 31 October 2024
cfDNA. This approach allows for the acquisition of ctDNA fragmentation features crucial for predicting gene expressions, such as Promoter Fragmentation...
59 KB (6,409 words) - 12:02, 30 December 2024
degradation processes (including cross-linking, deamination and fragmentation) ancient DNA is more degraded in comparison with present-day genetic material...
60 KB (6,343 words) - 13:02, 1 May 2025
chromosome 18 by 2.6-fold. Exposure of male workers to carbaryl increased DNA fragmentation in spermatozoa, and also increased sex chromosome disomy by 1.7-fold...
37 KB (3,586 words) - 11:07, 11 April 2025
include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, and chromosomal DNA fragmentation. It is now thought that- in a developmental...
57 KB (6,843 words) - 14:01, 27 April 2025
target. Sperm DNA fragmentation appears to be an important factor in the cause of male infertility, since men with high DNA fragmentation levels have significantly...
52 KB (6,032 words) - 23:20, 25 April 2025
DNA fragmentation factor subunit alpha (DFFA), also known as Inhibitor of caspase-activated DNase (ICAD), is a protein that in humans is encoded by the...
11 KB (1,405 words) - 12:00, 5 July 2023
dUTP Nick End Labeling assay), in genetics, a method for detecting DNA fragmentation Tunel (band), Yugoslav rock band Tunel (railroad station), railroad...
603 bytes (113 words) - 16:18, 18 February 2019
vomiting during pregnancy (NVP). For example: Sperm DNA Fragmentation: High levels of sperm DNA damage have been associated with abnormal placental development...
29 KB (2,963 words) - 08:38, 24 March 2025
S, Sabanegh E, Agarwal A (2010). "Semen characteristics and sperm DNA fragmentation in infertile men with low and high levels of seminal reactive oxygen...
4 KB (345 words) - 21:51, 23 April 2025
quality, as the selected ones have better motility, morphology, little DNA fragmentation and less quantity of reactive oxygen species (ROS). Another way to...
31 KB (3,636 words) - 14:34, 12 January 2025
irreversible condensation of chromatin), karyorrhexis (fragmentation of the nucleus and condensed DNA) and karyolysis (dissolution of the chromatin due to...
14 KB (1,555 words) - 06:23, 9 December 2024
(Xia et al., 2004). Exposure of male workers to carbaryl increased DNA fragmentation in spermatozoa, and also increased sex chromosome disomy by 1.7-fold...
5 KB (659 words) - 15:20, 17 April 2024
been suggested to be one of the deoxyribonucleases responsible for DNA fragmentation during apoptosis. DNase I binds to the cytoskeletal protein actin...
11 KB (1,397 words) - 14:36, 14 November 2024