• Thumbnail for EGR1
    factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. EGR-1 is a mammalian transcription factor. It was also named Krox-24...
    12 KB (1,504 words) - 14:02, 22 November 2022
  • Thumbnail for Transcription (biology)
    sites for EGR1 in the mammalian genome and about half of EGR1 binding sites are located in promoters and half in enhancers. The binding of EGR1 to its target...
    58 KB (6,780 words) - 04:35, 23 May 2024
  • sites for EGR1 in the mammalian genome and about half of EGR1 binding sites are located in promoters and half in enhancers. The binding of EGR1 to its target...
    26 KB (2,836 words) - 13:21, 3 December 2023
  • Thumbnail for DNA demethylation
    MCF-10A genome. The gene early growth response protein 1 (EGR1) is an immediate early gene (IEG). EGR1 can rapidly be induced by neuronal activity. The defining...
    42 KB (5,154 words) - 13:37, 14 February 2024
  • Reprogramming (section EGR1)
    levels independent of protein synthesis. EGR1 can rapidly be induced by neuronal activity. In adulthood, EGR1 is expressed widely throughout the brain...
    49 KB (5,387 words) - 17:07, 6 April 2024
  • sites for EGR1 in the mammalian genome and about half of EGR1 binding sites are located in promoters and half in enhancers. The binding of EGR1 to its target...
    54 KB (6,343 words) - 11:47, 7 November 2023
  • Thumbnail for Fear conditioning
    conditioning, Egr1 and Dnmt3A2 (shown to be an IEG by Oliveira et al.) affect DNA methylation, and thus expression, of many genes. Up-regulated EGR1 proteins...
    30 KB (3,770 words) - 16:15, 15 February 2024
  • Thumbnail for Epigenetics
    000 genome locations at which EGR1 protein can bind. EGR1 protein binds to DNA in gene promoter and enhancer regions. EGR1 recruits the demethylating enzyme...
    161 KB (18,430 words) - 14:53, 15 May 2024
  • Thumbnail for Transcription factor
    reprogramming. The transcription factor EGR1 recruits the TET1 protein that initiates a pathway of DNA demethylation. EGR1, together with TET1, is employed in...
    75 KB (8,019 words) - 20:38, 2 April 2024
  • Thumbnail for LSD
    of the Serotonin 2A Receptor Gene (HTR2A) or Early Growth Response Genes (EGR1-3) in Healthy Subjects". Frontiers in Neuroscience. 8: 423. doi:10.3389/fphar...
    162 KB (16,528 words) - 19:19, 15 May 2024
  • Thumbnail for TET enzymes
    This initiates the demethylation pathway. EGR1 is another example of a protein that recruits a TET enzyme. EGR1 has an important role in learning and memory...
    32 KB (3,984 words) - 05:42, 27 April 2024
  • described above, given an environmental cue egr1 will induce or suppress the transcription of other genes. Egr1 shows how social experience may trigger changes...
    15 KB (2,165 words) - 18:05, 3 November 2023
  • Thumbnail for Lipolysis
    lipolysis by facilitating the inhibitory effect of transcription factor Egr1 on transcription of adipose triglyceride lipase". The Journal of Biological...
    15 KB (1,555 words) - 02:19, 20 May 2024
  • Affected mice have altered levels of Arc,affecting synaptic activity, and EGR1, involved in memory trace encoding. Other neuropsychiatric illnesses such...
    17 KB (1,965 words) - 19:22, 2 April 2024
  • Thumbnail for TOE1
    Target of EGR1 protein 1 is a protein that in humans is encoded by the TOE1 gene. GRCh38: Ensembl release 89: ENSG00000132773 – Ensembl, May 2017 GRCm38:...
    5 KB (431 words) - 18:37, 11 October 2022
  • family of zinc finger transcription factors. Members of the family include: EGR1, EGR2, EGR3 and EGR4 Gómez-Martín D, Díaz-Zamudio M, Galindo-Campos M, Alcocer-Varela...
    908 bytes (86 words) - 17:50, 7 April 2022
  • form ternary complexes with SRF on EGR1 SREs. In addition, ELK1 and SAP1a can also form quaternary complexes on the Egr1 SREI. SAP1a activation by ERK may...
    3 KB (417 words) - 03:37, 17 September 2021
  • Thumbnail for Chromosome 5
    CXXC-type zing finger protein 5 DPYSL3: Dihydropyrimidinase-like protein 3 EGR1: early growth response protein 1 ERAP1: endoplasmic reticulum aminopeptidase...
    32 KB (2,298 words) - 22:55, 28 March 2024
  • phosphatase 1 (PP1), P/CAF 3 hours Heat shock or Serum HSPA1B, JUN, FOS, EGR1, MYC yes yes promoter & POLII pausing site DNA-PKcs, Ku70, γH2AX, TRIM28...
    57 KB (6,173 words) - 00:11, 11 December 2023
  • specific TF according to literature or domain structure – No motif [184] EGR1 ENSG00000120738 C2H2 ZF Known motif – High-throughput in vitro [185] MCGCCCMCGCA...
    374 KB (81 words) - 02:10, 23 September 2023
  • Thumbnail for Zinc finger
    known for its role in sequence-specific DNA-binding proteins such as Zif268 (Egr1). In such proteins, individual zinc finger domains typically occur as tandem...
    42 KB (4,825 words) - 19:40, 5 May 2024
  • break is EGR1. EGR1 is an important transcription factor in memory formation. It has an essential role in brain neuron epigenetic reprogramming. EGR1 recruits...
    63 KB (8,159 words) - 23:16, 5 May 2024
  • Thumbnail for Chromosome 5q deletion syndrome
    antiproliferative and antiangiogenic effects; and the candidate tumor suppressors EGR1, CTNNA1, and CDC25C. This syndrome affects bone marrow cells causing treatment-resistant...
    8 KB (701 words) - 15:54, 26 April 2024
  • Thumbnail for Chromosome 1
    Transmembrane protein 201 TMEM222: Transmembrane protein 222 TOE1: Target of EGR1 protein 1 TRABD2B: encoding protein Trab domain containing 2b TRAPPC3: Trafficking...
    46 KB (3,284 words) - 04:21, 11 April 2024
  • Thumbnail for Gene expression
    locations on the genome. The guidance is performed by association of TET1s with EGR1 protein, a transcription factor important in memory formation. Bringing TET1s...
    81 KB (9,242 words) - 21:24, 22 May 2024
  • Thumbnail for P1PK blood group system
    that differential binding of transcription factors early growth response 1 (EGR1) and runt-related transcription factor 1 (RUNX1) to the SNP rs5751348 genomic...
    13 KB (1,356 words) - 03:24, 10 February 2024
  • HGNC:1232 Q9GZT9 4780 EGLN2 HGNC:14660 Q96KS0 4781 EGLN3 HGNC:14661 Q9H6Z9 4782 EGR1 HGNC:3238 P18146 4783 EGR2 HGNC:3239 P11161 4784 EGR3 HGNC:3240 Q06889 4785...
    277 KB (17 words) - 23:17, 27 April 2024
  • Thumbnail for YIF1A
    finger protein with KRAB and SCAN domains 12) E2F transcription factor 1 EGR1, early growth response 1 GATA-binding factor 1 Transcription factor CP2-like...
    18 KB (1,710 words) - 03:36, 9 March 2024
  • Thumbnail for CEBPG
    C/EBPγ along with its regulator, the trauma-induced transcription factor EGR1, plays an important role in the development of chronic pain and mechanical...
    9 KB (1,124 words) - 06:28, 11 December 2023
  • Thumbnail for NAB2
    (5): 963–71. PMID 8649813. "Entrez Gene: NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)". Kabbinavar, F. F.; Hambleton, J; Mass, R. D.; Hurwitz...
    7 KB (850 words) - 18:48, 13 August 2023