initiation factor 4B is a protein that in humans is encoded by the EIF4B gene. eIF4B has been shown to interact with and stimulate the activity of eIF4A...
8 KB (957 words) - 12:15, 1 August 2023
trimer, the eIF4F complex functionally interacts with proteins including eIF4B and eIF4H. The unusual isoform of eIF4G, eIF4G2 or DAP5, also appears to...
7 KB (707 words) - 05:35, 18 January 2025
subunit has multiple human isoforms and there exist additional eIF4 proteins: eIF4B and eIF4H. eIF4G is a 175.5-kDa scaffolding protein that interacts with...
13 KB (1,595 words) - 17:00, 27 August 2024
connection. However, both mammalian and yeast eIF3 independently bind eIF1, eIF4B, and eIF5. Several subunits of eIF3 contain RNA recognition motifs (RRMs)...
22 KB (2,101 words) - 01:49, 14 June 2024
40S subunit in order to induce DEAD-box RNA helicase eIF4A, its cofactor eIF4B, and eIF4G activity. Eukaryotic initiation factors GRCh38: Ensembl release...
7 KB (828 words) - 07:55, 8 March 2023
P60842 4833 EIF4A2 HGNC:3284 Q14240 4834 EIF4A3 HGNC:18683 P38919 4835 EIF4B HGNC:3285 P23588 4836 EIF4E HGNC:3287 P06730 4837 EIF4E1B HGNC:33179 A6NMX2...
277 KB (17 words) - 18:34, 6 October 2024
Free S6K1 is then able to phosphorylate a number of its targets, including eIF4B. P70-S6 Kinase 1 has been shown to interact with: COASY, CSNK2B, EIF3B,...
18 KB (2,099 words) - 02:45, 16 May 2025
translation, as are components of the eIF4F complex (eIF4A, eIF4E, and eIF4G) and eIF4B, which are generally required for mRNA binding and unwinding of 5'UTR. Initiator...
5 KB (481 words) - 15:34, 22 January 2024
Factor 4A2 EIF4A3 EIF4A3 Eukaryotic Translation Initiation Factor 4A3 EIF4B EIF4B Eukaryotic translation Initiation factor 4B EIF4E EIF4E Eukaryotic Translation...
184 KB (12,563 words) - 05:08, 10 March 2025
of the same translation initiation factors; such as PABPC1, eIF4G, eIF3, eIF4B, eIF4A and eIF2. Translation is started when the 40S ribosomal subunit binds...
12 KB (1,489 words) - 15:46, 30 May 2024
A (eIF4A) and its cofactor eukaryotic translation initiation factor 4B (eIF4B). The helicase is required to remove hairpin loops that arise in the 5'...
69 KB (7,807 words) - 19:19, 19 September 2024
of the mTOR pathway. SF2/ASF increases the phosphorylation of rpS6 and eIF4B by S6K1. 9G8 increases the translation of unspliced mRNA with a constitutive...
27 KB (3,443 words) - 03:57, 30 October 2024
considerably improves in the presence of eIF4B and eIF4H, binding partners that modulate its activity. When eIF4B binds to eIF4A1, the helicase activity...
24 KB (2,591 words) - 04:53, 26 May 2025
eIF4 (eukaryotic initiation factor 4) as a whole complex made up of eIF4A, eIF4B, eIF4E, and eIF4G. eIF4F is used to refer to the complex that comprises...
13 KB (1,701 words) - 02:06, 1 December 2023
virion host shutoff protein is stimulated by translation initiation factors eIF4B and eIF4H". J Virol. 78 (9): 4684–99. doi:10.1128/JVI.78.9.4684-4699.2004...
7 KB (889 words) - 20:46, 16 September 2024
D10S102; DAZ1; DAZ2; DAZ3; DAZ4; DAZAP1; DAZL; DNAJC17; DND1; EIF3S4; EIF3S9; EIF4B; EIF4H; ELAVL1; ELAVL2; ELAVL3; ELAVL4; ENOX1; ENOX2; EWSR1; FUS; FUSIP1;...
12 KB (812 words) - 18:05, 2 November 2024
image. Most miRNA seem to congregate around the two conserved domains. EIF4B is known as eukaryotic translation initiation factor 4B and is needed to...
19 KB (1,681 words) - 01:11, 8 February 2025
proteins are referred to as eIF4F. For maximal activity; eIF4A also requires eIF4B (80 kDa), which itself is enhanced by eIF4H (25 kDa). A study conducted...
16 KB (1,828 words) - 07:58, 10 March 2024
The sequence for the secondary structure of the 3’ UTR are recognized by EIF4B and RBMX. FANCD2OS is moderately expressed in the human brain, placenta...
6 KB (375 words) - 03:48, 14 June 2023
respectively. The 5' untranslated region has predicted sites for binding by RBXM, EIF4B, and FUS. The 3' untranslated region has predicted sites for binding by...
18 KB (1,714 words) - 03:35, 27 May 2025
the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell...
10 KB (938 words) - 19:21, 8 July 2024
complex involved on pre-mRNA splicing and export of mRNA to the cytoplasm EIF4B eukaryotic translation factor 4B 8.05 88% 431-437 GCGGAAA Protein required...
33 KB (2,273 words) - 23:10, 27 May 2025
EIF3C, EIF3D, EIF3EIP, EIF3F, EIF3G, EIF3H, EIF3I EIF3J, EIF3K, EIF3S6, EIF4B, EIF4G2, and FBXO32. Eukaryotic initiation factor 3 (eIF3) GRCh38: Ensembl...
12 KB (1,367 words) - 01:10, 29 March 2024
binding proteins RBMX1, FUS, SFRS1, ACO1, and NONO. The 3' UTR is bound by EIF4B, A2BP1, and ZFP36. A single non-coding variant of FAM208b is transcribed...
22 KB (2,213 words) - 08:44, 30 April 2024
molecule contain sites for RNA-binding proteins, including RBMX, pum2, and EIF4B as well as microRNA binding sites. The 5'UTR also contains an upstream in-frame...
22 KB (1,817 words) - 20:14, 20 September 2023