Enzyme induction is a process in which a molecule (e.g. a drug) induces (i.e. initiates or enhances) the expression of an enzyme. Enzyme inhibition can...

spontaneously leave the enzyme, allowing the enzyme to resume its function. Reversible inhibitors produce different types of inhibition depending on whether...

birth) Induction chemotherapy, in medicine Enzyme induction and inhibition General anaesthesia Induction period, slow stage of a reaction Inductive cleavage...

comes from enzymes in the liver called cytochrome P450 oxidases, which are important in drug metabolism. Induction or inhibition of these enzymes can cause...

of the enzymes can either be stimulated (enzyme induction) or inhibited (enzyme inhibition). If a drug is metabolized by a CYP450 enzyme and drug B blocks...

transporter blockade, induction of transmitter release, and inhibition of transmitter breakdown. Cocaine is a monoamine transporter blocker and, thus, an indirect...

Janne; Turpeinen, Miia; Pelkonen, Olavi (May 5, 2025). "Inhibition and induction of CYP enzymes in humans: an update". Archives of Toxicology. 94 (11):...

the biosynthesis of an isozyme (enzyme induction) or by directly inhibiting the activity of the P450 (enzyme inhibition). A classical example includes...

this enzyme performs in a myriad of biological activities including apoptosis-induction, edema-induction, hemorrhaging, and inhibition or induction of platelet...

leaves the question concerning what causes inhibition of glucose oxidation. The discovery that HClO blocks induction of β-galactosidase by added lactose led...

follicles to grow continuously and maintain the anagen phase. Due to the anti-fibrotic activity of minoxidil inhibition of enzyme lysyl hydroxylase present...

Kojin Therapeutics and Ono Pharmaceutical has demonstrated that inhibition of glutamate-cysteine ligase (GCL), the rate-limiting enzyme in GSH biosynthesis...

systematic name peptidoglycan N-acetylmuramoylhydrolase) is an antimicrobial enzyme produced by animals that forms part of the innate immune system. It is a...

that inhibition of the enzyme might have extensive practical application for treatment of hormone-dependent breast cancer, alterations of ovarian and endometrial...

the induction time of fats and oils. Over time, the Rancimat method has become established, and it has been accepted into a number of national and international...

all benzodiazepines are metabolised by the CYP3A4 and CYP2D6 pathways, and inhibition of these enzymes results in a higher area under the curve (i.e., the...

system, or enzyme classification system was created to both standardize enzyme names, as well as allow for association of enzyme reaction type and function...

Jacob and Jacques Monod to determine how a biological cell knows which enzyme to synthesize. Their work on the lac operon won them the Nobel Prize in...

inhibition in terms of inhibition or induction of apoptosis demonstrate that bafilomycin's function is critically dependent on cellular context, and can...

active component of an intravenous anesthetic formulation used for induction and maintenance of general anesthesia. It is chemically termed 2,6-diisopropylphenol...

repair, induction of cellular hypoxia, inhibition of apoptosis, alteration of gene expression and modification of enzyme activity. Amifostine is believed to...

ketoconazole, levoketoconazole, shows 12-fold reduced potency in inhibition of this enzyme, and is under development for certain indications (e.g., Cushing's...

women. Ovulation inhibition is an antigonadotropic effect and is mediated by inhibition of the secretion of the gonadotropins, LH and FSH, from the pituitary...

first proposed by John Hopfield and Jacques Ninio, involved in DNA replication, immune system specificity, and enzyme-substrate recognition among many...

weevils Acanthoscelides obtectus and Zabrotes subfasciatus by binding via its N-terminal to the active site of the enzyme. Defensins with alpha-amylase-inhibitory...

(abbreviated CYP3A4) (EC 1.14.13.97) is an important enzyme in the body, mainly found in the liver and in the intestine, which in humans is encoded by CYP3A4...

Cyclooxygenase-3 (COX-3) is an enzyme that is encoded by the PTGS1 (COX1) gene, but is not functional in humans. COX-3 is the third and most recently discovered...

point towards inhibition of demethylase synthesis and/or induction of demetylase degradation. Unpublished observations of Venkatesan, Argus and Arcos suggest...

PMID 24966474. Iqbal J (July 2011). "An enzyme immobilized microassay in capillary electrophoresis for characterization and inhibition studies of alkaline phosphatases"...

Moexipril was an angiotensin converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure. Moexipril can...