Functional genomics is a field of molecular biology that attempts to describe gene (and protein) functions and interactions. Functional genomics make use...

Epistasis and functional genomics is the study of how genetic interactions, where one gene affects the expression of another gene, can be systematically...

Originally, the term epistasis specifically meant that the effect of a gene variant is masked by that of different gene. The concept of epistasis originated in...

approaches. Biology portal Hi-C (genomic analysis technique) Cognitive genomics Computational genomics Epigenomics Functional genomics GeneCalling, an mRNA profiling...

pattern, known as "antagonistic epistasis". Synergistic epistasis is central to some theories of the purging of mutation load and to the evolution of sexual...

expressed because of another genetic factor hindering their expression, this epistasis can make it impossible even for dominant alleles on certain other gene-loci...

Retrieved 15 November 2020. Pevsner, Jonathan (2009). Bioinformatics and functional genomics (2nd ed.). Hoboken, N.J: Wiley-Blackwell. ISBN 9780470085851. National...

this coefficient may be more robust to noise and is intuitively interpretable in terms of Batesonian epistasis. This approach was used to identify a new...

regarding gene and allele number, the distribution of allelic and mutational effects, and patterns of pleiotropy, dominance, and epistasis. There are several...

genetic phenomenon epistasis whereby the phenotypic effect of one mutation is dependent upon mutation(s) at other loci. While epistasis was originally conceived...

has blue or magenta alleles. This interaction between genes is called epistasis, with the second gene epistatic to the first. Many traits are not discrete...

twin Frequency histogram Fruiting body Full gene sequence Functional allele Functional genomics Fundamental number G-banding Galton Laboratory Gamete Gametophyte...

ISBN 978-0-87893-187-3. Phillips PC (2008). "Epistasis – the essential role of gene interactions in the structure and evolution of genetic systems". Nat. Rev...

chromosomal fragments. epistasis The collective action of multiple genes interacting during gene expression. A form of gene action, epistasis can be either additive...

scientist serving as chief of the autoimmunity and functional genomics section at the National Institute of Allergy and Infectious Diseases. She earned a Ph.D...

causal and noncausal sites, more than one causal site and epistasis. These indirect associations are not randomly distributed throughout the genome and are...

comparing Buchnera aphidicola and Escherichia coli, it was found that positive epistasis furthers gene loss while negative epistasis hinders it. List of disabled...

In genomics, a genome-wide association study (GWA study, or GWAS), is an observational study of a genome-wide set of genetic variants in different individuals...

Mendelian disorders. Background genetic effects (modifier genes), epistasis, somatic variation, and environmental factors all complicate the inference of causality...

Roberts and Company Publishers. Whitlock, M. C.; Bourguet, D. (2000). "Factors affecting the genetic load in Drosophila: synergistic epistasis and correlations...

forms: no epistasis (additive inheritance), synergistic (or positive) epistasis and antagonistic (or negative) epistasis. In synergistic epistasis, each additional...

Vodicka R (June 2013). "STAT6 - polymorphisms, haplotypes and epistasis in relation to atopy and asthma". Biomedical Papers of the Medical Faculty of the University...

member of the evolutionarily conserved RAD52 epistasis group, which additionally includes RAD51, RAD52, RAD55, and RAD57 factors. This group is believed to...

P, Charron D, Tron F (June 2002). "Epistasis between DSG1 and HLA class II genes in pemphigus foliaceus". Genes and Immunity. 3 (4): 205–10. doi:10.1038/sj...

mosaic – maternal effect – penetrance – complementation – suppression – epistasis – genetic linkage Model organisms: Drosophila – Arabidopsis – Caenorhabditis...

developing genomics tools to functionally dissect developmental programmes during embryogenesis. Furlong started her independent lab at EMBL in 2002, and was...

inbreeding decline and [of] the high yield of hybrids. There is little statistical evidence for contributions from overdominance and epistasis. But whether...

complex traits, making it an ideal system for functional genomics, quantitative trait locus (QTL) mapping, and genetic improvement of crops. A major part...

insects, and so in their evolutionary history as a whole. Both pleiotropy and epistasis have complex effects in this regard, with the simulations of Griswold...

comparison of mutational effects and epistasis across a wide range of bacterial species. Csaba Pal received several domestic and international awards, including...