Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. Mammalian mRNAs contain AU-rich elements (AREs)...
8 KB (1,045 words) - 16:32, 17 July 2025
component 7 has been shown to interact with: Exosome component 1, Exosome component 2, and Exosome component 6. GRCh38: Ensembl release 89: ENSG00000075914...
6 KB (717 words) - 04:09, 15 July 2025
Exosome component 4, also known as EXOSC4, is a human gene, which is part of the exosome complex. Exosome component 4 has been shown to interact with...
6 KB (777 words) - 05:46, 19 July 2025
Exosome component 10, also known as EXOSC10, is a human gene, the protein product of which (sometimes called PM/Scl-100) is part of the exosome complex...
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encoded by the EXOSC1 gene. This gene encodes a core component of the exosome complex. The mammalian exosome is required for rapid degradation of AU rich element-containing...
7 KB (782 words) - 05:46, 19 July 2025
Exosome component 3, also known as EXOSC3, is a human gene, which is part of the exosome complex. Mutations in EXOSC3 cause pontocerebellar hypoplasia...
6 KB (702 words) - 21:41, 15 July 2025
Exosome component 5, also known as EXOSC5, is a human gene, which is part of the exosome complex. Biallelic pathogenic variation in EXOSC5 causes autosomal...
9 KB (971 words) - 05:46, 19 July 2025
Exosome component 9, also known as EXOSC9, is a human gene, the protein product of which (sometimes called RRP45 or PM/Scl-75) is part of the exosome...
8 KB (797 words) - 05:46, 19 July 2025
The exosome complex (or PM/Scl complex, often just called the exosome) is a multi-protein intracellular complex capable of degrading various types of...
43 KB (4,589 words) - 17:33, 6 November 2024
system and the Complement component 2 protein attaches to Complement system 4 resulting in an immune response. Complement component 2 protein is critical for...
16 KB (2,068 words) - 16:58, 16 July 2025
β2 microglobulin (B2M) is a component of MHC class I molecules. MHC class I molecules have α1, α2, and α3 proteins which are present on all nucleated...
17 KB (2,118 words) - 15:48, 17 July 2025
DIS3L2 (category Genes on human chromosome 2)
similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading...
1 KB (153 words) - 04:05, 15 July 2025
Autoantibodies often found in these patients are the anti-PM/Scl (anti-exosome) antibodies. The symptoms that are seen most often are typical symptoms...
6 KB (597 words) - 04:26, 20 June 2025
exoribonucleolytic degradation. Extended hTR transcripts are also degraded by the RNA exosome. The 5’ ends of hTR transcripts are also additionally processed. TGS-1...
23 KB (2,549 words) - 18:46, 16 July 2025
CSPG4 (redirect from Neuron-glial antigen 2)
melanoma-associated chondroitin sulfate proteoglycan (MCSP) or neuron-glial antigen 2 (NG2), is a chondroitin sulfate proteoglycan that in humans is encoded by...
12 KB (1,498 words) - 16:13, 17 July 2025
epithelial-derived cell lines. Desmoglein-2 is the only desmoglein isoform expressed in cardiomyocytes. Desmoglein-2 is an integral component of desmosomes, which are...
20 KB (2,282 words) - 05:36, 19 July 2025
Angiotensin-converting enzyme 2 (ACE2) is an enzyme that can be found either attached to the membrane of cells (mACE2) in the intestines, kidney, testis...
45 KB (5,270 words) - 19:19, 10 June 2025
The serum amyloid P component (SAP) is the identical serum form of the amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal...
6 KB (744 words) - 18:35, 16 July 2025
TACSTD2 (redirect from Tumor-associated calcium signal transducer 2)
Kimura S, Fujiki K, Fujimaki T, Kanai A (2004). "Mutations in the membrane component, chromosome 1, surface marker 1 (M1S1) gene in gelatinous drop-like corneal...
11 KB (1,362 words) - 07:27, 19 July 2025
Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved...
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composed of multiple domains, as predicted by homology with complement component C3". The Biochemical Journal. 407 (1): 23–30. doi:10.1042/BJ20070764....
14 KB (1,667 words) - 14:59, 11 June 2025
to be larger, on average, than intracellularly-generated EVs known as exosomes. Microvesicles play a role in intercellular communication and can transport...
54 KB (6,074 words) - 21:14, 22 May 2025
contact with various components of exosome, Mtr4p helps in proper addition of RNA substrates of TRAMP complex to nuclear exosome. The difference between...
19 KB (2,325 words) - 20:23, 15 May 2025
agreed to acquire Quad Technologies. In August 2018, the company acquired Exosome Diagnostics for $250 million plus up to an additional $325 million in milestone...
12 KB (826 words) - 07:17, 31 August 2024
MASP2 (protein) (redirect from MASP-2 (protein))
mannose residues on the surface of a pathogen, MASP-2 is activated to cleave complement components C4 and C2 into C4a, C4b, C2a, and C2b. MASP1 (protein)...
11 KB (1,484 words) - 17:53, 16 July 2025
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial is an enzyme that in humans is encoded...
8 KB (968 words) - 17:08, 16 July 2025
Complement component 4B (Chido blood group) is a kind of the Complement component 4 protein that in humans is encoded by the C4B gene. This gene encodes...
8 KB (1,049 words) - 05:28, 19 July 2025
2′,3′-Cyclic-nucleotide 3'-phosphodiesterase (EC 3.1.4.37, CNPase, systematic name nucleoside-2′,3′-cyclic-phosphate 2′-nucleotidohydrolase) is an enzyme...
15 KB (1,637 words) - 16:06, 16 July 2025
Myelin P2 protein (redirect from Peripheral myelin protein 2)
Myelin P2 protein also peripheral myelin protein 2, is a protein that in humans is encoded by the PMP2 gene. Myelin protein P2 is a constituent of peripheral...
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EEF2 (redirect from Elongation factor 2)
Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene. It is the archaeal and eukaryotic counterpart of bacterial EF-G...
9 KB (1,045 words) - 05:40, 19 July 2025