Coagulation factor XII, also known as Hageman factor, is a plasma protein involved in coagulation. It is the zymogen form of factor XIIa (EC 3.4.21.38)...

Factor XII deficiency is a deficiency in the production of factor XII (FXII), a plasma glycoprotein and clotting factor that participates in the coagulation...

name for the factor is plasma thromboplastin component, given by an independent group in California. Hageman factor, now known as factor XII, was identified...

(exact frequency uncertain). It has been linked with mutations in the factor XII gene. Angioedema can be due to antibody formation against C1INH; this...

normal C1 inhibitor levels) is associated with mutations in genes for Factor XII, angiopoietin 1, plasminogen or kininogen 1. The pathophysiologic mechanisms...

prekallikrein, factor XII, factor XI, and factor IX). Factor XIa activates factor IX by selectively cleaving arg-ala and arg-val peptide bonds. Factor IXa, in...

protein inhibits activation of the plasma contact system by binding to factor XII and high molecular weight kininogen". Journal of Biological Chemistry...

releases endotoxin when it lyses. Endotoxin activates the Hageman factor (clotting factor XII), which causes disseminated intravascular coagulation (DIC)....

antibody that binds to the catalytic domain of activated factor XII (FXIIa). FXIIa is the first factor activated in the contact system, which leads to the...

In the contact activation system or CAS, three proteins in the blood, factor XII (FXII), prekallikrein (PK) and high molecular weight kininogen (HK), bind...

cleaved to produce kallikrein by activated Factor XII (Hageman factor). Prekallikrein is homologous to factor XI, and similarly consists of four apple domains...

for the activation of kallikrein and factor XII. It is also necessary for the activation of factor XI by factor XIIa. HMWK is also a precursor of bradykinin;...

inflammatory mediators in vivo. Production and release of transforming growth factor (TGF) beta from macrophages Production and release of interleukin 10 (IL-10)...

of factor XII and culminate in the activation of millions of times more fibrin molecules. Factor VII shares a common domain architecture with factors IX...

activate blood coagulation factor XII which is essential for blood clot formation. Factor XII, also called Hageman factor, initiates fibrin formation...

Pope Pius XII (Italian: Pio XII; born Eugenio Maria Giuseppe Giovanni Pacelli; 2 March 1876 – 9 October 1958) was the head of the Catholic Church and...

induce coagulation through contact activation of coagulation factor XII (Hageman factor). The silica particles are desiccants, which adsorb and hold water...

clotting factor molecules. The higher concentration of these remaining cells and molecules cause them to naturally clot faster. Kaolin activates factor XII, a...

system (CAS), also known as the intrinsic pathway, the binding of HK, factor XII (FXII), and prekallikrein (PK) to an anionic surface initiates blood coagulation...

takes place in the sequence: albumin; globulin; fibrinogen; fibronectin; factor XII, and HMWK. While the exact mechanism of action is still unknown many important...

other ligands in the circulation such as thrombin, P-selectin, factor XI, factor XII, high molecular weight kininogen as well as bacteria. GPIb-IX-V...

polycythemia vera (high red blood cell counts), and is an additional risk factor for complications.[citation needed] A very small number of people report...

evaluates coagulation factors I, II, V, VII and X, while the PTT evaluates coagulation factors I, II, V, VIII, IX, X, XI and XII. The analysis of both...

antibodies also activate the coagulation cascade (blood clotting system) via factor XII, which can lead to disseminated intravascular coagulation and kidney damage...

blood to clot upon activation of the intrinsic pathway by the addition of factor XII activators. The clotting time is based on a relative scale and requires...

autoactivation of factor XII while at high AAHA concentrations, factor XIIa activation increases at levels comparable to Apo-H that cause inhibition of factor XIIa...

Hageman may refer to: Hageman (surname) Hageman factor, another name for coagulation factor XII Places Hagemans Crossing, Ohio, an unincorporated place...

nonwoven material impregnated with kaolin, an inorganic mineral activating Factor XII, in turn accelerating natural clotting. Unlike the original zeolite formulation...

blood-related disorders. Ratnoff discovered the substance later known as Factor XII and was one of the primary contributors to the delineation of the exact...

disorders, partial deficiency of factor VIII:C, partial deficiency of factor XI:C, partial deficiency of factor XII:C, and an imbalance of plasminogen...