fibroblast growth factor receptors (FGFRs). FGF1 is also known as acidic fibroblast growth factor, and FGF2 is also known as basic fibroblast growth factor...
25 KB (3,126 words) - 10:38, 23 January 2025
The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of...
8 KB (827 words) - 14:53, 16 April 2025
via specific fibroblast growth factor receptor (FGFR) proteins, themselves a family of closely related molecules. Fibroblast growth factor protein was...
22 KB (2,698 words) - 17:05, 16 July 2024
Fibroblast growth factor receptor 3 (FGFR-3) is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster...
17 KB (1,844 words) - 17:02, 8 May 2025
Fibroblast growth factor receptor 1 (FGFR-1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
44 KB (5,003 words) - 14:24, 24 February 2025
Fibroblast growth factor 21 (FGF-21) is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast...
24 KB (3,038 words) - 23:40, 29 November 2024
Fibroblast growth factor receptor 2 (FGFR-2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is encoded by the FGFR2...
14 KB (1,745 words) - 09:02, 15 July 2024
Fibroblast growth factor 23 (FGF-23) is a protein and member of the fibroblast growth factor (FGF) family which participates in the regulation of phosphate...
16 KB (1,840 words) - 07:12, 2 November 2024
Fibroblast growth factor 1 (FGF-1) also known as acidic fibroblast growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1...
20 KB (2,311 words) - 22:01, 16 July 2024
Fibroblast growth factor 5(FGF5) Fibroblast growth factor 6(FGF6) Fibroblast growth factor 7(FGF7) Fibroblast growth factor 8(FGF8) Fibroblast growth...
10 KB (1,131 words) - 18:45, 6 May 2025
Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90...
28 KB (3,078 words) - 17:48, 25 January 2025
Fibroblast growth factor receptor 4 (FGFR-4) is a protein that in humans is encoded by the FGFR4 gene. FGFR4 has also been designated as CD334 (cluster...
10 KB (1,291 words) - 09:08, 15 July 2024
repair, and tumor progression. FGF8 signals primarily through fibroblast growth factor receptor 1 (FGFR1) to trigger downstream pathways involved in neural...
20 KB (2,532 words) - 04:09, 22 April 2025
outgrowth of neurites in PC12 cells. FGF18 signals through fibroblast growth factor receptor (FGFR) family, preferentially binding FGFR 3c (followed by...
16 KB (1,816 words) - 10:07, 9 May 2025
GRB2 (redirect from Growth factor receptor-bound protein 2)
Growth factor receptor-bound protein 2, also known as Grb2, is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2...
82 KB (9,365 words) - 09:44, 2 March 2025
Activation of other growth factor receptors such as fibroblast growth factor receptors or epidermal growth factor receptor can also be responsible. Acanthosis...
18 KB (1,783 words) - 11:16, 19 April 2025
epithelium. KGF is a small signaling molecule that binds to fibroblast growth factor receptor 2b (FGFR2b). For signalling to occur, a dimer is required...
2 KB (182 words) - 00:56, 11 June 2023
enzymatic activity include: Receptor tyrosine kinase, as in fibroblast growth factor receptor. Most enzyme-linked receptors are of this type. Serine/threonine-specific...
7 KB (350 words) - 19:02, 13 March 2024
Platelet-derived growth factor receptor A, also termed CD140a, is a receptor located on the surface of a wide range of cell types. The protein is encoded...
29 KB (3,358 words) - 23:42, 16 March 2025
Fibroblast growth factor receptor-like 1 is a protein that in humans is encoded by the FGFRL1 gene. The protein encoded by this gene is a member of the...
6 KB (842 words) - 01:10, 27 January 2024
Pfeiffer syndrome (category Cell surface receptor deficiencies)
big toes. Pfeiffer syndrome is caused by mutations in the fibroblast growth factor receptors FGFR1 and FGFR2. The syndrome is grouped into three types:...
14 KB (1,432 words) - 02:39, 3 January 2025
Adrenergic receptor Olfactory receptors Receptor tyrosine kinases Epidermal growth factor receptor Insulin Receptor Fibroblast growth factor receptors, High...
22 KB (2,480 words) - 14:02, 24 March 2025
fibroblast growth factor (FGF) activates a signaling pathway that positively regulates the PDGF receptors in OPCs. PDGF was one of the first growth factors...
24 KB (2,882 words) - 16:31, 25 October 2024
Fibroblast growth factor receptor substrate 2 is a protein that in humans is encoded by the FRS2 gene. FRS2 is an 80 kDa membrane-anchored signal transducing...
16 KB (1,851 words) - 19:13, 27 March 2024
cell culture system, rat kidney fibroblasts. Application of the transforming growth factors to normal rat kidney fibroblasts induces the cultured cells to...
6 KB (596 words) - 06:45, 1 January 2025
FGF5 (redirect from Fibroblast growth factor 5)
Fibroblast growth factor 5 is a protein that in humans is encoded by the FGF5 gene. The majority of FGF family members are glycosaminoglycan binding proteins...
19 KB (2,251 words) - 15:12, 25 April 2024
viz., FGF19 and FGF21) to their fibroblast growth factor receptors, is promoted via their interactions as co-receptors with β-klotho. Loss of β-Klotho...
38 KB (4,038 words) - 08:29, 11 April 2025
targeting vascular endothelial growth factor receptor, fibroblast growth factor receptor and platelet derived growth factor receptor. Ofev was developed by Boehringer...
34 KB (3,021 words) - 12:39, 5 August 2024
epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
60 KB (6,879 words) - 01:06, 1 March 2025
Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different...
67 KB (8,184 words) - 08:20, 28 December 2024