Folate transporter 1 is a protein which in humans is encoded by the SLC19A1 gene. Transport of folate compounds into mammalian cells can occur via receptor-mediated...
11 KB (1,284 words) - 13:04, 3 May 2025
The proton-coupled folate transporter is a protein that in humans is encoded by the SLC46A1 gene. The major physiological roles of PCFTs are in mediating...
22 KB (2,649 words) - 18:32, 9 June 2024
The folate-biopterin transporter (FBT) family (TC# 2.A.71) is a distant family within the major facilitator superfamily, most closely related to drug resistance...
3 KB (372 words) - 07:57, 16 April 2022
Folate, also known as vitamin B9 and folacin, is one of the B vitamins. Manufactured folic acid, which is converted into folate by the body, is used as...
106 KB (11,298 words) - 16:41, 9 May 2025
Folate deficiency, also known as vitamin B9 deficiency, is a low level of folate and derivatives in the body. This may result in megaloblastic anemia in...
29 KB (3,176 words) - 17:31, 16 January 2025
effector. As noted above, the AbgT family of transporters has been thought to contribute to bacterial folate biosynthesis by importing the catabolite...
8 KB (859 words) - 06:28, 6 August 2023
sequence. The thiamine transporter protein encoded by SLC19A2 has a 40% shared amino acid identity with the folate transporter SLC19A1. The N-terminal...
16 KB (1,882 words) - 00:20, 10 March 2024
Solute carrier family (redirect from Sodium-dependent organic anion transporter)
SLC17A9) vesicular amine transporter (SLC18A1, SLC18A2, SLC18A3) folate/thiamine transporter (SLC19A1, SLC19A2, SLC19A3) type III Na+-phosphate cotransporter...
35 KB (3,408 words) - 02:42, 30 November 2023
protein 1 (HCP1) was originally identified as mediating heme-Fe transport although it later emerged that it was the SLC46A1 folate transporter. HCP1 is...
12 KB (1,428 words) - 18:07, 13 February 2024
Publishing. pp. 3–. ISBN 978-1-61705-056-5. Zhao R, Aluri S, Goldman ID (2017). "The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome...
16 KB (1,334 words) - 15:12, 1 November 2024
Folate receptor 1 (Folate receptor alpha, FOLR1) is a protein that in humans is encoded by the FOLR1 gene. The protein encoded by this gene is a member...
15 KB (1,756 words) - 15:34, 10 February 2025
The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6...
22 KB (2,503 words) - 00:44, 4 March 2023
The mitochondrial folate transporter (MTF) is a transport protein that facilitates the transfer of tetrahydrofolate across the inner mitochondrial membrane...
4 KB (385 words) - 16:08, 12 February 2025
conformational shape through phosphorylation of amino acids with ATP. Glucose transporters are integral membrane proteins that mediate the transport of glucose...
17 KB (1,984 words) - 13:55, 20 April 2025
Hereditary folate malabsorption (HFM) is a rare autosomal recessive disorder caused by loss-of-function mutations in the proton-coupled folate transporter (PCFT)...
26 KB (2,754 words) - 15:32, 12 October 2024
Zinc transporter 1 is a protein which in humans is encoded by the SLC30A1 gene. SLC30A1 modulates zinc permeation through the L-type calcium channel....
6 KB (725 words) - 12:19, 17 January 2024
Antifolate (redirect from Folate antagonists)
and tend to have adverse effects on the bone marrow, skin, and hair. As folate is vital in the first trimester of pregnancy for healthy fetal development...
10 KB (751 words) - 12:35, 19 March 2025
The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that...
31 KB (3,438 words) - 05:47, 22 August 2024
In biology, an ion transporter is a transmembrane protein that moves ions (or other small molecules) across a biological membrane to accomplish many different...
17 KB (2,039 words) - 10:46, 15 November 2024
Membrane transport protein (redirect from Membrane transporter)
either channels or carriers (a.k.a. transporters, or permeases). Examples of channel/carrier proteins include the GLUT 1 uniporter, sodium channels, and potassium...
26 KB (2,656 words) - 14:08, 8 March 2025
Glutamate transporters are a family of neurotransmitter transporter proteins that move glutamate – the principal excitatory neurotransmitter – across...
24 KB (2,828 words) - 15:14, 24 September 2023
Folate Carrier (RFC) Family 2.A.49 Chloride Carrier/Channel (ClC) Family 2.A.50 The Glycerol Uptake (GUP) Family 2.A.51 The Chromate Ion Transporter (CHR)...
38 KB (5,159 words) - 15:41, 17 April 2024
Choline (redirect from 2-Hydroxy-N,N,N-trimethylethan-1-aminium)
single-nucleotide polymorphisms (genetic factors) affecting choline and folate metabolism are also relevant. Certain gut microbes also degrade choline...
60 KB (6,040 words) - 09:41, 16 April 2025
The dopamine transporter (DAT, also sodium-dependent dopamine transporter) is a membrane-spanning protein coded for in humans by the SLC6A3 gene (also...
84 KB (9,201 words) - 10:39, 12 December 2024
intermediate interferes with the normal bacterial synthesis of folic acid (folate). Folate is an essential metabolite for bacterial growth and replication because...
12 KB (982 words) - 14:24, 28 March 2025
Reduced Folate Carrier (RFC) Family (TC# 2.A.48) is a group of transport proteins that is part of the major facilitator superfamily. RFCs take up folate, reduced...
5 KB (624 words) - 13:41, 22 April 2022
Organic Anion Transporter (OAT) Family (organic-anion-transporting polypeptides, OATP) are membrane transport proteins or 'transporters' that mediate...
13 KB (1,503 words) - 11:33, 24 April 2025
carrier family 18 member 2 (SLC18A2) also known as vesicular monoamine transporter 2 (VMAT2) is a protein that in humans is encoded by the SLC18A2 gene...
29 KB (3,347 words) - 04:21, 10 March 2025
Antiporter (section Reduced folate carrier protein)
human reduced folate carrier/ThTr1 thiamine transporter chimaeras: role of the transmembrane domain 6/7 linker region in reduced folate carrier function"...
60 KB (7,840 words) - 00:16, 11 February 2025
two glycine transporters: glycine transporter 1 (GlyT1) and glycine transporter 2 (GlyT2). Excitatory amino acid transporter GABA transporter Glycine receptor...
1 KB (90 words) - 07:11, 16 April 2022