linker histone (H1) variants, which lack a distinct canonical isoform. The differences between the core canonical histones and their variants can be summarized...

diverse histone variants highlighting the functional links between variants and the delicate regulation of organism development. Histone variants proteins...

sequence variants of histone H3. These are denoted as Histone H3.1, Histone H3.2, Histone H3.3, Histone H3.4 (H3T), Histone H3.5, Histone H3.X and Histone H3...

with its parent histone octamer. Histone H4 is an important protein in the structure and function of chromatin, where its sequence variants and variable...

notable variants include H2A.1, H2A.2, H2A.X, and H2A.Z. H2A variants can be explored using "HistoneDB with Variants" database Changes in variant composition...

isoforms of histone H2B have been studied in depth, researchers have found that histone H2B variants serve important roles. If certain variants stopped functioning...

exists at individual sites. Some patterns of histone modification and the presence of some histone variants on DNA remain unchanged during mitosis and have...

or variants. The discovery of H1 variants in calf thymus preceded the discovery of core histone variants. In human and mouse cells 11 H1 variants have...

particles have been solved to date, including those containing histone variants and histones from different species. The structure of the nucleosome core...

appears that excess H3.3 can drive senescence. There are multiple variants of histone 2, the one most notably implicated in aging is macroH2A. The function...

well studied than the PTMs of other histones. Nucleosome Histone Chromatin Linker histone H1 variants Other histone proteins involved in chromatin: H2A...

factors, such as DNA methylation and hydroxymethylation. Different histone variants are incorporated into specific regions of the genome non-randomly....

and indicate that lack of functional histone H2A leads to embryonic lethality. Histone H2AZ is a variant of histone H2A, and is used to mediate the thermosensory...

Histone methylation is a process by which methyl groups are transferred to amino acids of histone proteins that make up nucleosomes, which the DNA double...

Histone H2A-Bbd type 1 also known as H2A Barr body-deficient is a histone protein variant that in humans is encoded by the H2AFB1 gene (H2A histone family...

The Histone Database is a comprehensive database of histone protein sequences including histone variants, classified by histone types and variants, maintained...

sliding") along the DNA, eject or assemble histones on/off of DNA or facilitate exchange of histone variants, and thus creating nucleosome-free regions...

Histone acetylation and deacetylation are the processes by which the lysine residues within the N-terminal tail protruding from the histone core of the...

propagation of histone modifications. In these regions, chromatin structure is probably controlled by incorporation of histone variants during nucleosome...

Core histone macro-H2A.1 is a protein that in humans is encoded by the H2AFY gene. Histones are basic nuclear proteins that are responsible for the nucleosome...

polyadenylation specificity factor 73 cuts mRNA between stem-loop and HDE Histone variants, such as H2A.Z or H3.3, however, have introns and are processed as...

important for solenoid formation. Histone variants can affect solenoid formation, for example H2A.Z is a histone variant of H2A, and it has a more acidic...

Histone H2A-Bbd type 2/3 also known as H2A Barr body-deficient is a histone protein that in humans is encoded by the H2AFB2 gene (H2A histone family,...

regulate gene expression. Histone modifications, which regulate the accessibility of chromatin for gene transcription. Chromatin variants, which are different...

responsible for the changing epigenetic profiles of cancerous cells. The histone variants of the H2A family are highly conserved in mammals, playing critical...

the nucleus in transplantation experiments, including the role of histone variants, and demethylation of the transplanted DNA. Gurdon has stated that...

nucleosome. Histone H1, and its other variants, are referred to as linker histones. Protruding from the linker histone are linker DNA. Chromatosomes are connected...

H2A histone family, member B3 is a protein that in humans is encoded by the H2AFB3 gene. Histones are basic nuclear proteins that are responsible for...

H2A histone family member X (usually abbreviated as H2AX) is a type of histone protein from the H2A family encoded by the H2AFX gene. An important phosphorylated...

nucleus reaches ~2 m. These DNA molecules are initially wrapped around histones to form nucleosomes, which are further compacted into chromatin fibers...