In molecular biology, initiation factors are proteins that bind to the small subunit of the ribosome during the initiation of translation, a part of protein...
12 KB (1,418 words) - 14:36, 25 May 2025
EIF2 (redirect from Eukaryotic initiation factor-2b)
Eukaryotic Initiation Factor 2 (eIF2) is a eukaryotic initiation factor. It is required for most forms of eukaryotic translation initiation. eIF2 mediates...
13 KB (1,538 words) - 19:25, 25 May 2025
Translation (biology) (redirect from Peptide initiation factor)
molecules (including splicing), initiation of these molecules with help of initiation factors (e.g., the initiation can include the circularization step...
36 KB (4,225 words) - 02:57, 1 June 2025
Eukaryotic initiation factors (eIFs) are proteins or protein complexes involved in the initiation phase of eukaryotic translation. These proteins help...
13 KB (1,595 words) - 17:00, 27 August 2024
A bacterial initiation factor (IF) is a protein that stabilizes the initiation complex for polypeptide translation. Translation initiation is essential...
20 KB (2,501 words) - 06:26, 28 October 2024
EIF4E (redirect from Eukaryotic translation initiation factor 4E)
translation initiation factor 4E, also known as eIF4E, is a protein in humans encoded by the EIF4E gene. eIF4E plays a central role in translation initiation and...
67 KB (7,657 words) - 15:30, 19 June 2025
factor (σ factor or specificity factor) is a protein needed for initiation of transcription in bacteria. It is a bacterial transcription initiation factor...
20 KB (2,045 words) - 13:47, 26 May 2025
Eukaryotic initiation factor 4F (eIF4F) is a heterotrimeric protein complex that binds the 5' cap of messenger RNAs (mRNAs) to promote eukaryotic translation...
7 KB (707 words) - 05:35, 18 January 2025
Eukaryotic translation (redirect from Cap-dependent initiation)
phases: initiation, elongation, termination, and recapping. Translation initiation is the process by which the ribosome and its associated factors bind to...
16 KB (2,003 words) - 04:43, 3 July 2025
Eukaryotic initiation factor 3 (eIF3) is a multiprotein complex that functions during the initiation phase of eukaryotic translation. It is essential...
22 KB (2,101 words) - 01:49, 14 June 2024
Eukaryotic translation initiation factor 4E-binding protein 1 (also known as 4E-BP1) is a protein that in humans is encoded by the EIF4EBP1 gene. It inhibits...
22 KB (2,697 words) - 03:27, 3 July 2025
are stalled translation pre-initiation complexes associated with 40S ribosomal subunits, translation initiation factors, poly(A)+ mRNA and RNA-binding...
184 KB (12,583 words) - 03:15, 10 July 2025
Bacterial initiation factor-2 is a bacterial initiation factor. IF2 binds to an initiator tRNA and controls the entry of tRNA onto the ribosome. IF2, bound...
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proteins. This domain is found at the C-terminus of several translation Initiation factors. It was first detected at the very C-termini of the yeast protein...
6 KB (639 words) - 09:54, 1 May 2024
Bacterial initiation factor 1 is a bacterial initiation factor. IF1 associates with the 30S ribosomal subunit in the A site and prevents an aminoacyl-tRNA...
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cellular initiation factor proteins involved in the translation of transcribed mRNA at the ribosome. The inhibition of these initiation factors prevents...
8 KB (920 words) - 09:52, 16 November 2024
molecular biology, translation initiation factor IF-3 (gene infC) is one of the three factors required for the initiation of protein biosynthesis in bacteria...
5 KB (513 words) - 03:04, 18 December 2024
methionine—can serve as a start codon and, along with sequences such as an initiation factor, initiates translation. In rare instances, start codons in the standard...
42 KB (1,606 words) - 23:52, 12 June 2025
Eukaryotic translation initiation factor 2A (eIF2A) is a protein that in humans is encoded by the EIF2A gene. The eIF2A protein is not to be confused...
8 KB (1,000 words) - 23:11, 2 December 2023
Transcription initiation factor TFIID subunit 10 is a protein that in humans is encoded by the TAF10 gene. Initiation of transcription by RNA polymerase...
11 KB (1,493 words) - 02:52, 24 December 2023
allows for translation initiation in a cap-independent manner, as part of the greater process of protein synthesis. Initiation of eukaryotic translation...
19 KB (1,775 words) - 01:59, 24 May 2025
EIF4G (redirect from Eukaryotic initiation factor 4G)
Eukaryotic translation initiation factor 4 G (eIF4G) is a protein involved in eukaryotic translation initiation and is a component of the eIF4F cap-binding...
8 KB (1,074 words) - 01:25, 9 January 2023
Archaeal initiation factors are proteins that are used during the translation step of protein synthesis in archaea. The principal functions these proteins...
6 KB (737 words) - 18:58, 17 January 2024
The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the...
16 KB (1,828 words) - 07:58, 10 March 2024
Initiation is a rite of passage marking entrance or acceptance into a group or society. It could also be a formal admission to adulthood in a community...
22 KB (2,500 words) - 00:04, 28 May 2025
Eukaryotic translation initiation factor 2 subunit 1 (eIF2α) is a protein that in humans is encoded by the EIF2S1 gene. The protein encoded by this gene...
13 KB (1,448 words) - 22:56, 26 May 2025
Eukaryotic translation initiation factor 3 subunit C like is a protein that in humans is encoded by the EIF3CL gene. The protein encoded by this gene...
1 KB (168 words) - 16:41, 28 October 2022
use as a treatment for cancers with elevated eukaryotic translation initiation factor eIF4E, especially acute myeloid leukemia (AML) as well as in head...
46 KB (4,719 words) - 13:29, 28 June 2025
DEAD box (section Translation initiation)
related to Ded1 plays a part in translation initiation by interacting with eukaryotic initiation factor 2 (eIF2). DDX3X DEAD/DEAH box helicase RNA helicase...
12 KB (1,436 words) - 16:39, 3 April 2024
transcription factors are necessary for transcription to occur. In bacteria, transcription initiation requires an RNA polymerase and a single GTF: sigma factor. In...
12 KB (1,317 words) - 16:05, 14 March 2025