• In molecular biology, initiation factors are proteins that bind to the small subunit of the ribosome during the initiation of translation, a part of protein...
    12 KB (1,418 words) - 14:36, 25 May 2025
  • Eukaryotic Initiation Factor 2 (eIF2) is a eukaryotic initiation factor. It is required for most forms of eukaryotic translation initiation. eIF2 mediates...
    13 KB (1,538 words) - 19:25, 25 May 2025
  • Thumbnail for Translation (biology)
    molecules (including splicing), initiation of these molecules with help of initiation factors (e.g., the initiation can include the circularization step...
    36 KB (4,225 words) - 02:57, 1 June 2025
  • Eukaryotic initiation factors (eIFs) are proteins or protein complexes involved in the initiation phase of eukaryotic translation. These proteins help...
    13 KB (1,595 words) - 17:00, 27 August 2024
  • A bacterial initiation factor (IF) is a protein that stabilizes the initiation complex for polypeptide translation. Translation initiation is essential...
    20 KB (2,501 words) - 06:26, 28 October 2024
  • Thumbnail for EIF4E
    translation initiation factor 4E, also known as eIF4E, is a protein in humans encoded by the EIF4E gene. eIF4E plays a central role in translation initiation and...
    67 KB (7,657 words) - 15:30, 19 June 2025
  • factorfactor or specificity factor) is a protein needed for initiation of transcription in bacteria. It is a bacterial transcription initiation factor...
    20 KB (2,045 words) - 13:47, 26 May 2025
  • Thumbnail for Eukaryotic initiation factor 4F
    Eukaryotic initiation factor 4F (eIF4F) is a heterotrimeric protein complex that binds the 5' cap of messenger RNAs (mRNAs) to promote eukaryotic translation...
    7 KB (707 words) - 05:35, 18 January 2025
  • phases: initiation, elongation, termination, and recapping. Translation initiation is the process by which the ribosome and its associated factors bind to...
    16 KB (2,003 words) - 04:43, 3 July 2025
  • Thumbnail for Eukaryotic initiation factor 3
    Eukaryotic initiation factor 3 (eIF3) is a multiprotein complex that functions during the initiation phase of eukaryotic translation. It is essential...
    22 KB (2,101 words) - 01:49, 14 June 2024
  • Thumbnail for EIF4EBP1
    Eukaryotic translation initiation factor 4E-binding protein 1 (also known as 4E-BP1) is a protein that in humans is encoded by the EIF4EBP1 gene. It inhibits...
    22 KB (2,697 words) - 03:27, 3 July 2025
  • Thumbnail for Stress granule
    are stalled translation pre-initiation complexes associated with 40S ribosomal subunits, translation initiation factors, poly(A)+ mRNA and RNA-binding...
    184 KB (12,583 words) - 03:15, 10 July 2025
  • Bacterial initiation factor-2 is a bacterial initiation factor. IF2 binds to an initiator tRNA and controls the entry of tRNA onto the ribosome. IF2, bound...
    1 KB (140 words) - 21:10, 12 November 2024
  • Thumbnail for EIF-W2 protein domain
    proteins. This domain is found at the C-terminus of several translation Initiation factors. It was first detected at the very C-termini of the yeast protein...
    6 KB (639 words) - 09:54, 1 May 2024
  • Bacterial initiation factor 1 is a bacterial initiation factor. IF1 associates with the 30S ribosomal subunit in the A site and prevents an aminoacyl-tRNA...
    2 KB (131 words) - 01:50, 14 June 2024
  • Thumbnail for 4EGI-1
    cellular initiation factor proteins involved in the translation of transcribed mRNA at the ribosome. The inhibition of these initiation factors prevents...
    8 KB (920 words) - 09:52, 16 November 2024
  • Thumbnail for Translation initiation factor IF-3
    molecular biology, translation initiation factor IF-3 (gene infC) is one of the three factors required for the initiation of protein biosynthesis in bacteria...
    5 KB (513 words) - 03:04, 18 December 2024
  • Thumbnail for DNA and RNA codon tables
    methionine—can serve as a start codon and, along with sequences such as an initiation factor, initiates translation. In rare instances, start codons in the standard...
    42 KB (1,606 words) - 23:52, 12 June 2025
  • Thumbnail for EIF2A
    Eukaryotic translation initiation factor 2A (eIF2A) is a protein that in humans is encoded by the EIF2A gene. The eIF2A protein is not to be confused...
    8 KB (1,000 words) - 23:11, 2 December 2023
  • Thumbnail for TAF10
    Transcription initiation factor TFIID subunit 10 is a protein that in humans is encoded by the TAF10 gene. Initiation of transcription by RNA polymerase...
    11 KB (1,493 words) - 02:52, 24 December 2023
  • allows for translation initiation in a cap-independent manner, as part of the greater process of protein synthesis. Initiation of eukaryotic translation...
    19 KB (1,775 words) - 01:59, 24 May 2025
  • Eukaryotic translation initiation factor 4 G (eIF4G) is a protein involved in eukaryotic translation initiation and is a component of the eIF4F cap-binding...
    8 KB (1,074 words) - 01:25, 9 January 2023
  • Archaeal initiation factors are proteins that are used during the translation step of protein synthesis in archaea. The principal functions these proteins...
    6 KB (737 words) - 18:58, 17 January 2024
  • The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the...
    16 KB (1,828 words) - 07:58, 10 March 2024
  • Thumbnail for Initiation
    Initiation is a rite of passage marking entrance or acceptance into a group or society. It could also be a formal admission to adulthood in a community...
    22 KB (2,500 words) - 00:04, 28 May 2025
  • Thumbnail for EIF2S1
    Eukaryotic translation initiation factor 2 subunit 1 (eIF2α) is a protein that in humans is encoded by the EIF2S1 gene. The protein encoded by this gene...
    13 KB (1,448 words) - 22:56, 26 May 2025
  • Thumbnail for EIF3CL
    Eukaryotic translation initiation factor 3 subunit C like is a protein that in humans is encoded by the EIF3CL gene. The protein encoded by this gene...
    1 KB (168 words) - 16:41, 28 October 2022
  • Thumbnail for Ribavirin
    use as a treatment for cancers with elevated eukaryotic translation initiation factor eIF4E, especially acute myeloid leukemia (AML) as well as in head...
    46 KB (4,719 words) - 13:29, 28 June 2025
  • Thumbnail for DEAD box
    related to Ded1 plays a part in translation initiation by interacting with eukaryotic initiation factor 2 (eIF2). DDX3X DEAD/DEAH box helicase RNA helicase...
    12 KB (1,436 words) - 16:39, 3 April 2024
  • Thumbnail for General transcription factor
    transcription factors are necessary for transcription to occur. In bacteria, transcription initiation requires an RNA polymerase and a single GTF: sigma factor. In...
    12 KB (1,317 words) - 16:05, 14 March 2025