DNA replication licensing factor MCM6 is a protein that in humans is encoded by the MCM6 gene. MCM6 is one of the highly conserved mini-chromosome maintenance...
14 KB (1,681 words) - 19:07, 12 April 2025
MCM6 gene helps control whether the LCT gene is turned on or off. At least several thousand years ago, some humans developed a mutation in the MCM6 gene...
68 KB (7,077 words) - 15:19, 27 May 2025
ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand binding...
60 KB (7,447 words) - 05:04, 1 June 2025
associated with longer survival times. Examples of unfavorable genes are MCM6 and TIMELESS; an example of a favorable gene is WIPI1. An increased...
157 KB (16,428 words) - 21:28, 29 May 2025
confirm the link between the lactose digestion phenotype in the Fulani to the MCM6/LCT locus by reporting the first GWAS of the lactase persistence trait. e...
129 KB (13,241 words) - 19:52, 26 May 2025
Mcm2/Cdc19/Nda1 Mcm2 Mcm2 Mcm3 Mcm3 Mcm3 Mcm3 Cdc54/Mcm4 Cdc21 DPA Mcm4 Cdc46/Mcm5 Mcm5/Nda4 Mcm5 Mcm5 Mcm6 Mcm6/Mis5 Mcm6 Mcm6 Cdc47/Mcm7 Mcm7 Mcm7 mcm7...
21 KB (2,339 words) - 22:38, 18 March 2025
transcripts, causing decreased LPH expression after weaning. Biology portal MCM6 Lactase persistence Järvelä I, Torniainen S, Kolho KL (2009). "Molecular...
22 KB (2,101 words) - 16:19, 4 May 2025
to lower. A2 milk Babcock test (determines the butterfat content of milk) MCM6 Bovine Meat and Milk Factors Dairy and health Fermented milk products Health...
4 KB (521 words) - 23:09, 18 April 2025
associated with two polymorphisms: C/T 13910 and G/A 22018 located in the MCM6 gene. This gene difference eliminates the shutdown in lactase production...
245 KB (27,677 words) - 20:52, 3 May 2025
ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand binding...
113 KB (12,563 words) - 03:12, 16 December 2024
HGNC:6946 O60318 9355 MCM4 HGNC:6947 P33991 9356 MCM5 HGNC:6948 P33992 9357 MCM6 HGNC:6949 Q14566 9358 MCM7 HGNC:6950 P33993 9359 MCM8 HGNC:16147 Q9UJA3 9360...
277 KB (17 words) - 18:41, 6 October 2024
associated with lactase expression. They are all located in a region of the gene MCM6 upstream of LCT. This region is considered as an enhancer region for the...
64 KB (7,391 words) - 18:42, 1 June 2025
OCCM (ORC-Cdc6-Cdt1-MCM) complex shows that the Cdt1-CTD interacts with the Mcm6-WHD. In metazoans, Cdt1 activity during the cell cycle is tightly regulated...
121 KB (14,916 words) - 04:06, 3 January 2025
ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand binding...
3 KB (336 words) - 03:59, 2 December 2024
shown to interact with: Cell division cycle 7-related protein kinase, MCM2, MCM6, MCM7, ORC1L, ORC2L, ORC3L, ORC4L, ORC5L, ORC6L, and Replication protein...
11 KB (1,271 words) - 03:21, 25 December 2024
DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by...
8 KB (990 words) - 21:08, 28 December 2023
were mcm1, mcm2, mcm3, mcm5 and mcm10. Later on, others identified Mcm4, Mcm6 and Mcm7 in yeasts and other eukaryotes based on homology to Mcm2p, Mcm3p...
24 KB (3,042 words) - 22:16, 29 October 2022
persistence is determined predominantly by a single-base mutation in the MCM6 gene and ancient DNA data show that this mutation became common only within...
21 KB (2,780 words) - 13:13, 16 December 2023
has been shown to interact with: ATM, CHAF1A, CHEK1, FANCM, FEN1, H2AFX, MCM6 MLH1 P53, RAD51L3, RAD51, RPA1, TOP3A, TP53BP1, WRN, and XRCC2. GRCh38: Ensembl...
21 KB (2,565 words) - 06:29, 24 September 2024
are reported. CDC45-related protein has been shown to interact with: MCM3, MCM6, MCM7, ORC1L, and ORC6L. GRCh38: Ensembl release 89: ENSG00000093009 – Ensembl...
9 KB (1,112 words) - 16:33, 14 October 2024
ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand binding...
6 KB (634 words) - 22:52, 2 December 2023
ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand binding...
9 KB (1,103 words) - 12:15, 20 March 2024
Nojima H (1999). "Cell growth-regulated expression of mammalian MCM5 and MCM6 genes mediated by the transcription factor E2F". Oncogene. 18 (14): 2299–309...
10 KB (1,223 words) - 05:36, 5 April 2024
ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand binding...
6 KB (740 words) - 17:22, 3 December 2023
with: AKAP8, Cell division cycle 7-related protein kinase, MCM3, MCM4, MCM5, MCM6, MCM7, ORC1L, ORC2L, ORC4L, ORC5L, and Replication protein A1. Mini Chromosome...
13 KB (1,600 words) - 02:11, 3 December 2023
Mizuno T, You Z, Hanaoka F (2002). "Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity". J. Biol...
12 KB (1,439 words) - 01:55, 12 October 2024
Replication protein A1 has been shown to interact with: BRCA2, BLM, MCM2, MCM4, MCM6, MCM7, MUTYH, ORC2L, ORC6L, P53, RPA2, RPA3, TIPIN, TP53BP1, and XPA. DNA-binding...
13 KB (1,549 words) - 16:10, 4 January 2024
the derived OCA2 allele associated with blue eye color, or the derived MCM6 allele associated with lactase persistence. However, they were found to carry...
40 KB (4,842 words) - 04:29, 5 May 2025
Cell division cycle 7-related protein kinase, DBF4, MCM2, MCM3, MCM4, MCM5, MCM6, MNAT1, ORC1L, ORC2L, ORC3L, ORC5L, Replication protein A1, Retinoblastoma...
14 KB (1,647 words) - 21:46, 18 August 2023
division cycle 7-related protein kinase, Cyclin-dependent kinase 2, MCM2, MCM4, MCM6, MCM7, MYST2, ORC2, ORC4, ORC5, and SKP2. GRCh38: Ensembl release 89: ENSG00000085840...
12 KB (1,433 words) - 06:31, 27 December 2023