The MRN complex (MRX complex in yeast) is a protein complex consisting of Mre11, Rad50 and Nbs1 (also known as Nibrin in humans and as Xrs2 in yeast)...

MRN may refer to: Macquarie Media (ASX: MRN), an Australian media company Michigan Radio Network, a satellite-distributed news service in Michigan, U...

and related protein domains. A complex of the three proteins MRE11, RAD50 and NBS1 (XRS2 in yeast), called the MRN complex in humans, recruits ATM to double...

repair pathway, the MRN complex (which consists of Mre11, Rad50 and NBS1) is attracted to the broken DNA ends and other MRN complexes to keep the broken...

another MRN complex, the MDC1 protein can sense the DNA damage by binding to the γH2AX flag through its BRCT domain and brings the bound MRN complex to the...

NBS1/hMre11/RAD50(N/M/R, more commonly referred to as MRN) double strand DNA break repair complex. This complex recognizes DNA damage and rapidly relocates to...

mutants defective in Ppmre11 or Pprad50 (that encode key proteins of the MRN complex, the principal sensor of DNA double-strand breaks) showed that these...

a budding yeast homolog of the mammalian Mre11-Rad50-Nbs1 (MRN) DNA damage repair complex. Cells are able to accurately repair DNA double-strand breaks...

strand breaks. The MRN complex (composed of Mre11, Rad50, and Nbs1) form immediately at the site of double strand break. This MRN complex recruits ATM to...

DNA contributes to its ability to inhibit the nuclease activity of the MRN complex as well as the nuclease activity of Mre11 alone. This may explain a role...

exist in the cell as a complex, along with a third protein expressed by the hRad50 gene. This complex, known as the MRN complex, plays an important role...

kinase found in colorectal cancer. WDCP has also been identified in the MRN complex, which processes double-stranded breaks in DNA. WDCP is located in chromosome...

interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage". EMBO Rep. 9 (8): 795–801. doi:10.1038/embor...

double-strand breaks (DSBs). TRRAP associates with the MRN complex and when TRRAP is removed, the complex shows reduced cDNA end-joining activity. Hence, TRRAP...

first several steps. After a double-strand break occurs, the MRX complex (MRN complex in humans) binds to DNA on either side of the break. Next a resection...

the protein mutated in AT, ATM, interacts with the MRE11/RAD50/NBS1 (MRN) complex. Other syndromes with clinical features similar to Nijmegen Breakage...

assemble on the extensive γH2AX-modified chromatin are the MRN complex (a protein complex consisting of Mre11, Rad50 and Nbs1), RAD51 and the ATM kinase...

integrity. Genes Ppmre11 and Pprad50 of P. patens encode components of the MRN complex, the principal sensor of DNA double-strand breaks. These genes are necessary...

two known substrates for this ubiquitin ligases; p53 and the MRN complex. The MRN complex, if not bound by the E1B-55K/E4orf6 ubiquitin ligase, will treat...

break repair. This protein forms a complex with MRE11 and NBS1 (also known as Xrs2 in yeast). This MRN complex (MRX complex in yeast) binds to broken DNA ends...

that provide a platform to recruit proteins involved in HRR repair. The MRN complex, consisting of Mre11, Rad50 and NBS1, carries out the initial steps of...

where this complex is called the MRX complex). Before resection can start, CtBP1-interacting protein (CtIP) needs to bind to the MRN complex so that the...

which is a mutation in the damage response kinase ATM – and BRCA1 or MRN complex mutations that play a role in responding to DNA damage. When the above...

the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates...

through turns 3 and 4. MRN Lead Pit Reporter Steve Post, Jason Toy, Alan Cavanna & Jacklyn Drake worked pit road for the radio side for MRN. "2025 schedule"...

Announcer Dave Moody called the action for MRN when the field raced down the backstretch. Lead Pit Reporter for MRN Steve Post, Chris Wilner, Brienne Pedigo...

which relies on DMC1, fails. MCM8 forms a complex with MCM9 that is required for DNA resection by the MRN complex (MRE11-RAD50-NBS1) at double strand breaks...

adjacent promoter. For AAV, the hairpins can bind to MRE11/Rad50/NBS1 (MRN) complexes and Ku70/80 heterodimers, which are involved in sensing and repairing...

April 22, 2018. "Entry List". MRN.com. Motor Racing Network. May 21, 2018. Retrieved May 21, 2018. "First Practice Results". MRN.com. Motor Racing Network...

April 19, 2019. "Entry List". MRN.com. Motor Racing Network. May 21, 2019. Retrieved May 21, 2019. "First Practice Results". MRN.com. Motor Racing Network...