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    MaxamGilbert sequencing is a method of DNA sequencing developed by Allan Maxam and Walter Gilbert in 1976–1977. This method is based on nucleobase-specific...
    6 KB (669 words) - 14:26, 19 December 2024
  • Thumbnail for DNA sequencing
    DNA. In 1976, Gilbert and Maxam, invented a method for rapidly sequencing DNA while at Harvard, known as the MaxamGilbert sequencing. The technique...
    136 KB (15,491 words) - 20:13, 9 May 2025
  • Thumbnail for Walter Gilbert
    regulatory protein. Together with Allan Maxam, Gilbert developed a new DNA sequencing method, MaxamGilbert sequencing, using chemical methods developed by...
    19 KB (1,736 words) - 08:47, 15 March 2025
  • Thumbnail for Sanger sequencing
    cheaper and easier sequence assembly. MaxamGilbert sequencing Second-generation sequencing Third-generation sequencing Chait, Edward; Page, Guy; Hunkapiller...
    28 KB (3,350 words) - 19:28, 12 May 2025
  • laboratory of Walter Gilbert. Walter Gilbert and Allan Maxam developed a DNA sequencing method - now called Maxam-Gilbert sequencing - which combined chemicals...
    3 KB (270 words) - 03:33, 5 December 2022
  • Thumbnail for Whole genome sequencing
    genome). The DNA sequencing methods used in the 1970s and 1980s were manual; for example, MaxamGilbert sequencing and Sanger sequencing. Several whole...
    115 KB (9,584 words) - 10:45, 11 May 2025
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    Science. pp. 48–49. ISBN 978-0-08-096156-9. Maxam AM, Gilbert W (February 1977). "A new method for sequencing DNA". Proc Natl Acad Sci U S A. 74 (2): 560–4...
    68 KB (7,540 words) - 09:03, 9 May 2025
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    2001 as one of the two fundamental methods for sequencing DNA fragments (the other being the MaxamGilbert method) but the Sanger method is both the "most...
    10 KB (1,181 words) - 03:24, 27 January 2025
  • Read (biology) (category DNA sequencing)
    throughput and sequencing speed have been developed. Sanger and Maxam-Gilbert sequencing technologies were classified as the First Generation Sequencing Technology...
    16 KB (2,055 words) - 00:23, 27 June 2024
  • groups - Fredrick Sanger’s enzymatic didoxy DNA sequencing technique and the Allen Maxam and Walter Gilbert chemical degradation technique. Following these...
    29 KB (3,085 words) - 22:03, 2 December 2023
  • Thumbnail for DNA sequencer
    doi:10.1101/gr.078212.108. ISSN 1088-9051. PMC 2577856. PMID 18714091. Gilbert W, Maxam A (1973). "The Nucleotide Sequence of the lac Operator". Proc Natl...
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  • Thumbnail for Genomics
    Gilbert and Allan Maxam of Harvard University independently developed the Maxam-Gilbert method (also known as the chemical method) of DNA sequencing,...
    79 KB (7,644 words) - 14:46, 31 March 2025
  • plot (bioinformatics) Sequence analysis Maxam, A M; Gilbert, W (February 1977). "A new method for sequencing DNA". Proceedings of the National Academy...
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  • Thumbnail for DNA footprinting
    Ph.D. and Albert Schmitz, Ph.D. modified the pre-existing Maxam-Gilbert chemical sequencing technique to bind specifically to the lac repressor protein...
    48 KB (5,621 words) - 15:28, 30 April 2025
  • radiolabelled DNA fragment. Lanes "GA" and "TC" are Maxam-Gilbert chemical sequencing lanes, see DNA Sequencing. The lane labelled "control" is for quality control...
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  • Thumbnail for Anthony Cashmore
    samples. Subsequently, Allan Maxam and Walter Gilbert employed the hydrazine degradation approach to develop MaxamGilbert sequencing, the first widely adopted...
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  • Thumbnail for Ray Wu
    1016/0022-2836(75)90213-2. ISSN 0022-2836. PMID 1100841. Maxam, A M; Gilbert, W (February 1977). "A new method for sequencing DNA". Proceedings of the National Academy...
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  • Thumbnail for Jürgen Brosius
    sequenced the first large ribosomal RNAs via their genes utilizing the Maxam-Gilbert sequencing method. It took ~2.5 years to sequence the 7.5 kilobases encompassing...
    18 KB (2,480 words) - 10:02, 15 March 2025
  • Thumbnail for Biochip
    Biochemistry, Worth Publishers, New York, 2000 A. M. Maxam and W. Gilbert, "A new method for sequencing DNA," Proc. Natl. Acad. Sci. 74, pp. 560–564, 1977...
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  • Thumbnail for Molecular genetics
    molecular cloning.  The development of DNA sequencing techniques in the late 1970s, first by Maxam and Gilbert, and then by Frederick Sanger, was pivotal...
    31 KB (3,815 words) - 16:38, 26 March 2025
  • Thumbnail for Gel electrophoresis
    neurotoxin in its liquid and powdered forms. Traditional DNA sequencing techniques such as Maxam-Gilbert or Sanger methods used polyacrylamide gels to separate...
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    Machine Signiant, 2020. Retrieved 9 June 2020. Maxam, A M; Gilbert, W (February 1977). "A new method for sequencing DNA". Proceedings of the National Academy...
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  • fibrosis, thyroid cancer, and breast cancer. Donis-Keller, Helen; Maxam, Allan M.; Gilbert, Walter (1977). "Mapping adenines, guanines, and pyrimidines in...
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  • Thumbnail for Timeline of biology and organic chemistry
    hydrothermal vents on the Galapagos Rift. 1977 – Walter Gilbert and Allan Maxam present a rapid DNA sequencing technique which uses cloning, base destroying chemicals...
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  • 1007/978-4-431-87771-4_9, ISBN 978-4-431-87770-7 Maxam, A. M.; Gilbert, W. (1977-02-01). "A new method for sequencing DNA". Proceedings of the National Academy...
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  • Thumbnail for Alkaline phosphatase
    (7): 801–804. doi:10.1093/protein/4.7.801. PMID 1798702. Maxam AM, Gilbert W (1980). "Sequencing end-labeled DNA with base-specific chemical cleavages"...
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  • Thumbnail for DNA binding site
    doi:10.1016/S0022-2836(61)80072-7. PMID 13718526. S2CID 19804795. Gilbert W, Maxam A (1973). "The nucleotide sequence of the lac operator". Proceedings...
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    1038/271501a0. PMID 622185. S2CID 4216649. Tonegawa S, Maxam AM, Tizard R, Bernard O, Gilbert W (March 1978). "Sequence of a mouse germ-line gene for...
    38 KB (4,660 words) - 16:36, 26 February 2025
  • Retrieved 12 January 2024 – via Newspapers.com. Tonegawa S, Maxam AM, Tizard R, Bernard O, Gilbert W (March 1978). "Sequence of a mouse germ-line gene for...
    47 KB (5,853 words) - 21:36, 25 April 2025
  • ISSN 1476-4687. PMID 622185. S2CID 4216649. Tonegawa, S; Maxam, A M; Tizard, R; Bernard, O; Gilbert, W (March 1978). "Sequence of a mouse germ-line gene for...
    69 KB (8,036 words) - 08:02, 28 October 2024