• Thumbnail for Michael addition reaction
    chemistry, the Michael reaction or Michael 1,4 addition is a reaction between a Michael donor (an enolate or other nucleophile) and a Michael acceptor (usually...
    27 KB (2,826 words) - 19:31, 22 May 2025
  • Thumbnail for Chemical reaction
    Organic Reactions. doi:10.1002/0471264180. ISBN 978-0-471-26418-7. Hunt, Ian. "Chapter 18: Enols and Enolates — The Michael Addition reaction". University...
    66 KB (8,057 words) - 20:26, 4 June 2025
  • Thumbnail for Nucleophilic conjugate addition
    conjugate addition is a type of organic reaction. Ordinary nucleophilic additions or 1,2-nucleophilic additions deal mostly with additions to carbonyl...
    6 KB (625 words) - 20:20, 5 March 2024
  • The Suzuki reaction or Suzuki coupling is an organic reaction that uses a palladium complex catalyst to cross-couple a boronic acid to an organohalide...
    35 KB (3,984 words) - 17:56, 24 May 2025
  • The Stetter reaction is a reaction used in organic chemistry to form carbon-carbon bonds through a 1,4-addition reaction utilizing a nucleophilic catalyst...
    19 KB (2,357 words) - 19:34, 9 March 2023
  • The Vilsmeier–Haack reaction (also called the Vilsmeier reaction) is the chemical reaction of a substituted formamide (1) with phosphorus oxychloride and...
    5 KB (457 words) - 18:59, 26 September 2024
  • and Miles Corporation in the United States. It utilizes the aza-Michael addition reaction. These products are then used in coatings, adhesives, sealants...
    8 KB (781 words) - 10:38, 25 May 2025
  • The aldol reaction (aldol addition) is a reaction in organic chemistry that combines two carbonyl compounds (e.g. aldehydes or ketones) to form a new...
    40 KB (4,256 words) - 12:17, 6 June 2025
  • alkylation Nitro-Mannich reaction Crabbé reaction Aza-Baylis-Hillman reaction – Mannich addition to an enone Smith, Michael B.; March, Jerry (2007). March's...
    10 KB (1,042 words) - 15:42, 2 June 2025
  • Thumbnail for Nitro-Mannich reaction
    The nitro-Mannich reaction (or aza-Henry reaction) is the nucleophilic addition of a nitroalkane (or the corresponding nitronate anion) to an imine, resulting...
    26 KB (2,894 words) - 15:33, 22 May 2025
  • Thumbnail for Hydroamination
    Hydroamination (category Addition reactions)
    Hydroamination reactions occur spontaneously only for electrophilic alkenes and some dienes, but these are known by other names (e.g. Michael addition reaction); "hydroamination"...
    19 KB (1,795 words) - 23:21, 2 June 2025
  • uniform polymer networks. Thiol-ene reactions are known to proceed through a Michael addition pathway. These reactions are catalyzed by either a base or...
    25 KB (2,808 words) - 12:29, 23 May 2025
  • Thumbnail for Johnson–Corey–Chaykovsky reaction
    Johnson and developed significantly by E. J. Corey and Michael Chaykovsky. The reaction involves addition of a sulfur ylide to a ketone, aldehyde, imine, or...
    22 KB (2,314 words) - 02:29, 26 May 2025
  • Arthur Michael (August 7, 1853 – February 8, 1942) was an American organic chemist who is best known for the Michael reaction. Arthur Michael was born...
    6 KB (665 words) - 09:54, 24 February 2025
  • Thumbnail for Multiple Michael/aldol reaction
    Multiple Michael/aldol reaction (or domino Michael/aldol reaction) is a consecutive series of reactions composed of either Michael addition reactions or aldol...
    3 KB (338 words) - 05:04, 15 August 2023
  • Thumbnail for Nitroethylene
    In addition to standard nucleophilic addition reactions on the C=C bond, nitroethylene can serve as a Michael acceptor in a Michael addition reaction. A...
    8 KB (846 words) - 07:20, 28 May 2025
  • Thumbnail for Lawsone
    reacts chemically with the protein keratin in skin and hair via a Michael addition reaction, resulting in a strong permanent stain that lasts until the skin...
    7 KB (687 words) - 23:45, 5 August 2024
  • transformations termed Tandem Michael-aldol reactions, that sequentially combine Michael addition and aldol reaction into a single reaction. As is the case with...
    15 KB (1,742 words) - 15:32, 24 May 2025
  • Thumbnail for Diels–Alder reaction
    In organic chemistry, the Diels–Alder reaction is a chemical reaction between a conjugated diene and a substituted alkene, commonly termed the dienophile...
    69 KB (7,937 words) - 05:25, 26 May 2025
  • Thumbnail for Grignard reaction
    by "A more modern interpretation extends the scope of the reaction to include the addition of Grignard reagents to a wide variety of electrophilic substrates...
    12 KB (1,096 words) - 23:09, 23 May 2025
  • Dimedone is prepared from mesityl oxide and diethyl malonate via a Michael addition reaction. Dimedone is in equilibrium with its tautomer in solution — in...
    4 KB (235 words) - 20:37, 26 May 2025
  • Oxidative addition and reductive elimination are two important and related classes of reactions in organometallic chemistry. Oxidative addition is a process...
    10 KB (1,210 words) - 14:57, 11 January 2025
  • Alkynylation (category Addition reactions)
    In organic chemistry, alkynylation is an addition reaction in which a terminal alkyne (−C≡CH) is added to a carbonyl group (C=O) to form an α-alkynyl...
    12 KB (1,249 words) - 06:08, 3 April 2025
  • The Sandmeyer reaction is a chemical reaction used to synthesize aryl halides from aryl diazonium salts using copper salts as reagents or catalysts. It...
    16 KB (1,738 words) - 11:35, 22 April 2025
  • Hydrocyanation (category Addition reactions)
    hydrocyanation is a process for conversion of alkenes to nitriles. The reaction involves the addition of hydrogen cyanide and requires a catalyst if the substrate...
    9 KB (1,053 words) - 00:32, 25 May 2025
  • The Friedel–Crafts reactions are a set of reactions developed by Charles Friedel and James Crafts in 1877 to attach substituents to an aromatic ring. Friedel–Crafts...
    22 KB (2,159 words) - 16:16, 24 May 2025
  • Thumbnail for Thiol-yne reaction
    coupling. Click chemistry Michael addition Radical addition Thiol-ene reaction March, Jerry (1985). Advanced Organic Chemistry: Reactions, Mechanisms, and Structure...
    18 KB (1,743 words) - 09:38, 28 May 2025
  • Thumbnail for Aldol condensation
    first (addition) stage of the process—the aldol reaction itself—as catalyzed by aldolases. However, the first step is formally an addition reaction rather...
    18 KB (1,816 words) - 18:28, 25 May 2025
  • the Baylis–Hillman, Morita–Baylis–Hillman, or MBH reaction is a carbon–carbon bond-forming reaction between an activated alkene and a carbon electrophile...
    24 KB (2,831 words) - 07:34, 31 May 2025
  • condensation is a nucleophilic addition of an active hydrogen compound to a carbonyl group followed by a dehydration reaction in which a molecule of water...
    7 KB (729 words) - 10:15, 12 February 2025