The Na–K–Cl cotransporter (NKCC) is a transport protein that aids in the secondary active transport of sodium, potassium, and chloride into cells. In...

are electrogenic and couples 2 Na+, 1 Cl− and 1 GABA for inward translocation. K+Cl− Symporter – The K+-Cl− cotransporter family consists of four specific...

symporter (also known as Na+-Cl− cotransporter, NCC or NCCT, or as the thiazide-sensitive Na+-Cl− cotransporter or TSC) is a cotransporter in the kidney which...

diuretics are pharmacological agents that primarily inhibit the Na-K-Cl cotransporter located on the luminal membrane of cells along the thick ascending...

microglobulin, arginine vasopressin and nitric oxide into CSF. A Na-K-Cl cotransporter and Na/K ATPase found on the surface of the choroid endothelium, appears...

The concentrations of K+ and Cl− ions are high inside the cell due to the activities of Na+/K+ ATPase and NKCC cotransporter, respectively. Hence, their...

Sodium (Na+), potassium (K+) and chloride (Cl−) ions are reabsorbed from the urine by secondary active transport by a Na–K–Cl cotransporter (NKCC2)....

acts by inhibiting the luminal Na–K–Cl cotransporter in the thick ascending limb of the loop of Henle, by binding to the Na-K-2Cl transporter, thus causing...

sodium/glucose cotransporter 2 (SGLT2) is a protein that in humans is encoded by the SLC5A2 (solute carrier family 5 (sodium/glucose cotransporter)) gene. SGLT2...

for creating urinary casts. The thick ascending limb symporter: Na-K-Cl cotransporter. Descending limb of loop of Henle This article incorporates text...

out of the cell. Ions are moved into the epithelial cells by a Na-K-Cl cotransporter, also in the basolateral membrane. Increases in sodium opens the...

while the NaCl symporters are specifically inhibited by thiazide. One member of the CCC family, the thiazide-sensitive NaCl cotransporter (NCC) of man...

surface (lumen side), cells of the DCT have a thiazide-sensitive Na-Cl cotransporter and are permeable to Ca, via the TRPV5 channel. On the basolateral...

Sodium-dependent glucose cotransporters (or sodium-glucose linked transporter, SGLT) are a family of glucose transporter found in the intestinal mucosa...

effect of the Na+/K+-ATPase pump by stimulating the outward transport of Na+, and therefore, the inward transport of K+. Na-K-Cl cotransporter is the therapeutic...

Sodium/bile acid cotransporter also known as the Na+-taurocholate cotransporting polypeptide (NTCP) or liver bile acid transporter (LBAT) is a protein...

insufficiency. Hypercalcemia also causes natriuresis by blocking the Na-K-Cl cotransporter (NKCC) in the medullary thick ascending limb of the loop of Henle...

chloride cotransporter (NCC), basolateral Na-K-Cl symporter (NKCC1), and potassium chloride cotransporter (KCC1) located within the kidney. CCCs mediate...

Sodium/glucose cotransporter 1 (SGLT1) also known as solute carrier family 5 member 1 is a protein in humans that is encoded by the SLC5A1 gene which...

K^{+}}+g_{Na^{+}}E_{eq,Na^{+}}+g_{Cl^{-}}E_{eq,Cl^{-}}}{g_{K^{+}}+g_{Na^{+}}+g_{Cl^{-}}}}} or reformulated E m = g K + g t o t E e q , K + + g N a + g t o...

Ileal sodium/bile acid cotransporter, also known as apical sodium–bile acid transporter (ASBT) and ileal bile acid transporter (IBAT), is a bile acid:sodium...

Gamba G (July 2000). "Characterization of the thiazide-sensitive Na(+)-Cl(-) cotransporter: a new model for ions and diuretics interaction". American Journal...

DB, Nelson-Williams C, Farhi A, Finberg K, Burleson L, et al. (June 2001). "Mutations in the Na-Cl cotransporter reduce blood pressure in humans". Hypertension...

all transporter proteins (SGLT1), the sodium–glucose cotransporter. Yu, SP; Choi, DW (June 1997). "Na+-Ca2+ exchange currents in cortical neurons: concomitant...

kinase of the Na-K-Cl cotransporter (NKCC1)". J. Biol. Chem. 278 (30): 27347–53. doi:10.1074/jbc.M301899200. PMID 12740379. Piechotta K, Garbarini N,...

are an isoform of the Na-K-Cl cotransporter. Phosphorylation of these proteins results in increase activity of the cotransporter. Chronic administration...

by the SLC12A6 gene. This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular...

mutations directly or indirectly involving the Na-K-2Cl cotransporter are key. The Na-K-2Cl cotransporter is involved in electroneutral transport of one...

Sodium-dependent phosphate transport protein 2A, also known as Na+-Pi cotransporter 2a (NaPi-2a), is a protein in humans that is encoded by the SLC34A1...

expression and high levels of a transporter known as NKCC1 (Na+/K+ chloride cotransporter 1), which moves chloride ions into cells. Thus, during embryonic...