• Neurotrophic factor receptors or neurotrophin receptors are a group of growth factor receptors which specifically bind to neurotrophins (neurotrophic...
    5 KB (670 words) - 10:25, 10 April 2025
  • Thumbnail for Brain-derived neurotrophic factor
    Brain-derived neurotrophic factor (BDNF), or abrineurin, is a protein that, in humans, is encoded by the BDNF gene. BDNF is a member of the neurotrophin...
    50 KB (5,881 words) - 13:31, 5 May 2025
  • The ciliary neurotrophic factor receptor, also known as CNTFR, binds the ciliary neurotrophic factor. This receptor and its cognate ligand support the...
    2 KB (146 words) - 00:52, 1 December 2023
  • Neurotrophic factors (NTFs) are a family of biomolecules – nearly all of which are peptides or small proteins – that support the growth, survival, and...
    16 KB (1,784 words) - 04:08, 6 January 2024
  • Thumbnail for Ciliary neurotrophic factor
    Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene. The protein encoded by this gene is a polypeptide hormone and neurotrophic...
    15 KB (1,748 words) - 16:47, 2 October 2024
  • Thumbnail for Tropomyosin receptor kinase B
    Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type...
    39 KB (4,393 words) - 05:21, 26 March 2025
  • Thumbnail for Low-affinity nerve growth factor receptor
    nerve growth factor. p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3...
    37 KB (4,235 words) - 04:17, 19 March 2025
  • Angiogenesis Bone growth factor Cytokine Growth factor receptor Human Genome Organisation Mitogen Neurotrophic factor Receptor (biochemistry) Signal transduction...
    10 KB (1,131 words) - 18:45, 6 May 2025
  • Thumbnail for Leukemia inhibitory factor receptor
    systems, including the ciliary neurotrophic factor, growth hormone and prolactin. Leukemia inhibitory factor receptor has been shown to interact with...
    11 KB (1,325 words) - 16:37, 6 April 2024
  • Thumbnail for Tropomyosin receptor kinase A
    Tropomyosin receptor kinase A (TrkA), also known as high affinity nerve growth factor receptor, neurotrophic tyrosine kinase receptor type 1, or TRK1-transforming...
    28 KB (3,328 words) - 15:54, 29 October 2024
  • Thumbnail for Glial cell line-derived neurotrophic factor
    Glial cell line-derived neurotrophic factor (GDNF) is a protein that, in humans, is encoded by the GDNF gene. GDNF is a small protein that potently promotes...
    25 KB (2,883 words) - 22:38, 25 January 2025
  • Thumbnail for Interleukin-6 receptor
    other cytokines. Interleukin-6 receptor has been shown to interact with Interleukin 6 and ciliary neurotrophic factor. Cluster of differentiation Anti-IL-6...
    11 KB (1,446 words) - 18:05, 6 March 2025
  • Thumbnail for Tropomyosin receptor kinase C
    Tropomyosin receptor kinase C (TrkC), also known as NT-3 growth factor receptor, neurotrophic tyrosine kinase receptor type 3, or TrkC tyrosine kinase...
    30 KB (3,901 words) - 17:05, 28 November 2024
  • Thumbnail for Neurotrophin
    [citation needed] Neurotrophin-4 (NT-4) is a neurotrophic factor that signals predominantly through the TrkB receptor tyrosine kinase. It is also known as NT4...
    28 KB (3,081 words) - 19:11, 28 November 2024
  • Thumbnail for Nerve growth factor
    Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival...
    27 KB (3,110 words) - 09:14, 8 March 2025
  • Thumbnail for Nerve injury
    McLaurin DL, Anderson KJ, Lee N (1999). "Regulation of ciliary neurotrophic factor receptor alpha in sciatic motor neurons following axotomy". Neuroscience...
    34 KB (4,114 words) - 16:09, 15 May 2025
  • Thumbnail for Epidermal growth factor receptor
    growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
    60 KB (6,879 words) - 01:06, 1 March 2025
  • Thumbnail for Neurotrophin-4
    humans is encoded by the NTF4 gene. It is a neurotrophic factor that signals predominantly through the TrkB receptor tyrosine kinase. NT-4 was first discovered...
    11 KB (1,241 words) - 12:35, 9 January 2024
  • Thumbnail for Fibroblast growth factor receptor 1
    Fibroblast growth factor receptor 1 (FGFR-1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
    44 KB (5,003 words) - 14:24, 24 February 2025
  • fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of proteins...
    8 KB (827 words) - 14:53, 16 April 2025
  • Thumbnail for Janus kinase 1
    IL-13R), the gp130 receptor family (e.g. IL-6R, IL-11R, LIF-R, OSM-R, cardiotrophin-1 receptor (CT-1R), ciliary neurotrophic factor receptor (CNTF-R), neurotrophin-1...
    21 KB (2,423 words) - 20:04, 16 October 2024
  • Thumbnail for Neurotrophin-3
    this gene, NT-3, is a neurotrophic factor in the NGF (Nerve Growth Factor) family of neurotrophins. It is a protein growth factor which has activity on...
    14 KB (1,820 words) - 07:02, 1 January 2025
  • Thumbnail for RET proto-oncogene
    The RET proto-oncogene encodes a receptor tyrosine kinase for members of the glial cell line-derived neurotrophic factor (GDNF) family of extracellular...
    21 KB (2,387 words) - 07:04, 7 April 2025
  • Thumbnail for GFRA2 (gene)
    cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are...
    6 KB (812 words) - 13:47, 11 June 2022
  • Thumbnail for Receptor tyrosine kinase
    Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90...
    28 KB (3,078 words) - 17:48, 25 January 2025
  • Thumbnail for Insulin-like growth factor 1
    growth factor (IGF) system. This system consists of three ligands (insulin, IGF-1 and IGF-2), two tyrosine kinase receptors (insulin receptor and IGF-1R...
    34 KB (4,512 words) - 06:26, 2 May 2025
  • Thumbnail for GDF15
    binding to glial cell-derived neurotrophic factor family receptor alpha-like (GFRAL) and the recruitment of the receptor tyrosine kinase RET in the hindbrain...
    14 KB (1,444 words) - 05:06, 27 December 2024
  • Thumbnail for Hepatocyte growth factor receptor
    Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
    59 KB (6,731 words) - 19:27, 17 March 2025
  • Thumbnail for Glycoprotein 130
    Glycoprotein 130 (category Type I cytokine receptors)
    such as cardiotrophin 1 (CT-1), leukemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), oncostatin M (OSM), and IL-11. There are also...
    18 KB (2,203 words) - 19:49, 17 March 2025
  • Thumbnail for CRLF1
    complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of...
    7 KB (931 words) - 16:56, 15 February 2024