An oncomir (also oncomiR) is a microRNA (miRNA) that is associated with cancer. MicroRNAs are short RNA molecules about 22 nucleotides in length. Essentially...

expression by downregulating them. Mutations in such microRNAs (known as oncomirs) can lead to activation of oncogenes. Antisense messenger RNAs could theoretically...

in humans is encoded by the ANP32A gene. It is one of the targets of an oncomiR, MIRN21. Acidic leucine-rich nuclear phosphoprotein 32 family member A...

abnormalities in the heart and vascular system. It is one of the targets of an oncomiR, MIRN21. In humans mutations of this gene result in autosomal dominant...

PTEN is inhibited by sarcopoterium. PTEN is one of the targets of the oncomiR, MIRN21. Cell lines with known PTEN mutations include: prostate: LNCaP...

also have links with cancer and accordingly are sometimes referred to as "oncomirs". In malignant B cells miRNAs participate in pathways fundamental to B...

production and lifespan, and the up-regulation and down-regulation of oncomirs. Given their role in presentation, HSPs are useful as immunologic adjuvants...

PMC 9080362. PMID 34967592. Medina PP, Nolde M, Slack FJ (September 2010). "OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma"...

involved in tumor invasion and metastasis. It is one of the targets of an oncomiR, MIRN21. GRCh38: Ensembl release 89: ENSG00000122707 – Ensembl, May 2017...

in humans is encoded by the PDCD4 gene. It is one of the targets of an oncomiR, MIRN21. This gene encodes a protein localized to the nucleus in proliferating...

is called Oncomir-1 because all members have been connected with inducing enhanced cell proliferation and suppression of apoptosis. Oncomir-1 has 2 paralogs...

PMC 3521625. PMID 23152446. Esquela-Kerscher A, Slack FJ (April 2006). "Oncomirs - microRNAs with a role in cancer". Nature Reviews. Cancer. 6 (4): 259–269...

"Targeting glioma stem cells by functional inhibition of a prosurvival oncomiR-138 in malignant gliomas". Cell Reports. 2 (3): 591–602. doi:10.1016/j...

implicated in a wide variety of malignancies and are sometimes referred to as oncomirs. The oncogenic potential of these non-protein encoding genes was first...

PMC 3892675. Reshmi, G.; Radhakrishna Pillai, M. (2008). "Beyond HPV: oncomirs as new players in cervical cancer". FEBS Letters. 582 (30): 4113–4116....

Potential for Human Diseases: MicroRNAs, miR-143 and -145, Function as Anti-oncomirs and the Application of Chemically Modified miR-143 as an Anti-cancer Drug"...