The Paal–Knorr synthesis is a reaction used to synthesize substituted furans, pyrroles, or thiophenes from 1,4-diketones. It is a synthetically valuable...
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The Knorr pyrrole synthesis is a widely used chemical reaction that synthesizes substituted pyrroles (3). The method involves the reaction of an α-amino-ketone...
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methods for synthesizing pyrroles exist, such as the Knorr Pyrrole Synthesis and Paal-Knorr Synthesis. Below is one published mechanism for the reaction:...
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give a glycoside Knorr pyrrole synthesis, a widely used chemical reaction that synthesizes substituted pyrroles Paal–Knorr synthesis, a reaction that...
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Ludwig Knorr (2 December 1859 – 4 June 1921) was a German chemist. Together with Carl Paal, he discovered the Paal–Knorr synthesis, and the Knorr quinoline...
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starting materials for several organic transformations, including the Paal–Knorr synthesis of furans and pyrroles. Traditionally utilized catalysts for the...
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Furan (section Synthesis of furans)
4-diketones with phosphorus pentoxide (P2O5) in the Paal–Knorr synthesis. Many routes exist for the synthesis of substituted furans. Furan in nature and commerce...
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Pyrrole (redirect from Piloty–Robinson pyrrole synthesis)
(bonded to the next carbon to) a carbonyl group (2). In the Paal–Knorr pyrrole synthesis, a 1,4-dicarbonyl compound reacts with ammonia or a primary amine...
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synthesis Fischer indole synthesis Gewald reaction Hantzsch pyridine synthesis Larock indole synthesis Paal–Knorr synthesis Pictet–Spengler reaction Pomeranz–Fritsch...
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roseophilin (e.g., those of Trost, Fürstner, Salamone) are based upon the Paal-Knorr synthesis, and two others are based on the Nazarov cyclization reaction (those...
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acetonylacetone. 1,4-Diketones are useful precursors to heterocycles via the Paal–Knorr synthesis, which gives pyrroles: This reactivity is the basis of the neurotoxicity...
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4,7-Dihydroisoindole (section Synthesis)
unstable isoindole was performed 1985. It was based on the classical Paal-Knorr synthesis under conditions which probably harmed the electron-rich pyrrole...
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Oxo synthesis Oxy-Cope rearrangement Oxymercuration Oxidation of alcohols to carbonyl compounds Ozonolysis Paal–Knorr pyrrole synthesis Paal–Knorr synthesis...
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1883: Claus process by Carl Friedrich Claus 1884: Paal–Knorr synthesis by Carl Paal and Ludwig Knorr 1885–1886: Discovery of germanium by Clemens Winkler...
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Ludwig Knorr: Chemist, who together with Carl Paal, discovered the Paal-Knorr synthesis, and the Knorr quinoline synthesis and Knorr pyrrole synthesis. Robert...
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Overhauser Ovshinsky effect – Stanford R. Ovshinsky Paal–Knorr synthesis – Carl Paal and Ludwig Knorr Pareto chart, distribution, efficiency, index, principle...
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Lamellarin D (section Synthesis)
Steglich synthesis features an oxidative coupling of two benzylic carbons, as well as a Paal-Knorr pyrrole synthesis. The Banwell group’s synthesis of lamellarin...
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Thiophene (section Synthesis and production)
dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Specialized thiophenes can be synthesized similarly using Lawesson's...
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Friedrich Loeffler in 1884. Paal-Knorr Synthesis was initially reported independently by German chemists Carl Paal and Ludwig Knorr as a method for the preparation...
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