Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for...
55 KB (6,180 words) - 10:18, 9 May 2025
polymerase α, DNA polymerase ε, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA) onto chromatin. Within a Xenopus nucleus-free system...
121 KB (14,916 words) - 04:06, 3 January 2025
Antinuclear antibody (redirect from Anti-nuclear antibody)
bind to contents of the cell nucleus. In normal individuals, the immune system produces antibodies to foreign proteins (antigens) but not to human proteins...
55 KB (6,260 words) - 02:26, 24 February 2025
Ki-67 (protein) (redirect from Ki-67 antigen)
Ki-67 (protein) has been shown to interact with CBX3. PCNA - Proliferating Cell Nuclear Antigen, expressed during the DNA synthesis. Immunofluorescent antibody...
10 KB (1,365 words) - 02:06, 17 June 2024
Kathleen M, So Antero G (Jul 2002). "Direct interaction of proliferating cell nuclear antigen with the small subunit of DNA polymerase delta". J. Biol....
8 KB (899 words) - 17:43, 23 March 2024
anticancer medication which acts as a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) and is in Phase I clinical trials at City of Hope as...
6 KB (589 words) - 21:09, 7 January 2025
for RFC-dependent loading of the replication sliding clamp, proliferating cell nuclear antigen (PCNA), in an orientation-specific manner, such that one face...
37 KB (4,458 words) - 00:33, 14 May 2025
failures could be lethal to the cell. Further research implicates the supplementary role of proliferating cell nuclear antigen (PCNA) to DNA ligase I's function...
34 KB (4,470 words) - 07:49, 11 November 2024
from a specific subunit of DNA polymerase delta called the proliferating cell nuclear antigen (PCNA). The N-terminal and C-terminal domains of PCNA are...
23 KB (2,044 words) - 07:04, 10 March 2024
Conversion from mitosis to meiosis: morphology and expression of proliferating cell nuclear antigen (PCNA) and Dmc1 during newt spermatogenesis. Dev Growth Differ...
36 KB (3,835 words) - 03:38, 1 February 2025
P21 (category Cell cycle regulators)
activity via ubiquitin ligase activity. p21 interacts with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory...
34 KB (3,939 words) - 06:53, 4 May 2025
polymerases. A bypass platform is provided to these polymerases by Proliferating cell nuclear antigen (PCNA). Under normal circumstances, PCNA bound to polymerases...
132 KB (16,176 words) - 11:20, 23 April 2025
exhibits increased processivity when interacting with the proliferating cell nuclear antigen (PCNA). As well, the multisubunit protein replication factor...
2 KB (259 words) - 21:21, 11 December 2023
Similarly, proliferating cell nuclear antigen (PCNA) is a protein associated with cell proliferation that is upregulated in proliferating cells, making it...
13 KB (1,559 words) - 06:51, 1 January 2025
P53 (redirect from Antigen NY-CO-13)
Prosperi E (December 2001). "UV-induced DNA incision and proliferating cell nuclear antigen recruitment to repair sites occur independently of p53-replication...
131 KB (14,361 words) - 00:12, 13 May 2025
strand by PCNA (Proliferating Cell Nuclear Antigen). PCNA forms typical patterns in the nucleus of the cell through which the current cell cycle can be determined...
9 KB (1,265 words) - 11:50, 29 October 2024
somatic cells, localizes to replication foci, has a 10–40-fold preference for hemimethylated DNA and interacts with the proliferating cell nuclear antigen (PCNA)...
159 KB (18,196 words) - 23:55, 9 May 2025
NF-κB (redirect from Nuclear factor-kappa B)
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription...
90 KB (9,838 words) - 18:55, 5 May 2025
"Interaction of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair". Biochemistry...
23 KB (2,642 words) - 21:34, 20 February 2024
Retinoblastoma protein (section Cell cycle suppression)
which push the cell through the cell cycle by activating cyclin-dependent kinases, and a molecule called proliferating cell nuclear antigen, or PCNA, which...
79 KB (9,501 words) - 00:55, 6 March 2025
MCL1 (redirect from Myeloid cell leukemia sequence 1)
"Regulation of apoptosis and cell cycle progression by MCL1. Differential role of proliferating cell nuclear antigen". The Journal of Biological Chemistry...
13 KB (1,490 words) - 19:54, 2 January 2024
Antibody (redirect from Receptors, antigen, b-cell)
each B cell can produce antibodies containing only one kind of variable chain. Following activation with antigen, B cells begin to proliferate rapidly...
126 KB (13,957 words) - 01:37, 19 March 2025
negatively regulated by direct interaction with proliferating cell nuclear antigen". Genes to Cells. 6 (9): 815–24. doi:10.1046/j.1365-2443.2001.00460...
30 KB (3,557 words) - 05:39, 17 August 2024
synthesis by DNA polymerase epsilon in the presence of PCNA (proliferating cell nuclear antigen), RFC (replication factor C) and RPA (replication protein...
3 KB (336 words) - 03:59, 2 December 2024
and POLD4 creating the other subunits that interact with Proliferating Cell Nuclear Antigen (PCNA), which is a DNA clamp that allows Pol δ to possess...
59 KB (7,100 words) - 18:11, 10 February 2025
reassociate with the DNA. An example of such a DNA clamp is PCNA (proliferating cell nuclear antigen) found in S. cervesiae. Multiple DNA polymerases have specialized...
6 KB (826 words) - 20:25, 10 September 2023
Ubiquitin (section Renal cell carcinoma)
also has a role in the trafficking some membrane proteins. Proliferating cell nuclear antigen (PCNA) is a protein involved in DNA synthesis. Under normal...
101 KB (11,338 words) - 19:50, 22 April 2025
delta p50 subunit. The encoded protein also interacts with proliferating cell nuclear antigen. Some transcripts of this gene overlap in a tail-to-tail orientation...
8 KB (891 words) - 21:04, 13 October 2022
DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase". J. Biol. Chem. 285 (29): 22196–201...
13 KB (1,576 words) - 12:36, 23 December 2023
topoisomerase II A, the FLAP endonuclease and the processing factor proliferating cell nuclear antigen. Other proteins include DNA dependent RNA polymerase II and...
27 KB (3,021 words) - 18:50, 4 April 2025