In molecular biology, protein aggregation is a phenomenon in which intrinsically-disordered or mis-folded proteins aggregate (i.e., accumulate and clump...

Computational methods that use protein sequence and/ or protein structure to predict protein aggregation. The table below, shows the main features of...

Dobson CM (July 2005). "Prediction of "aggregation-prone" and "aggregation-susceptible" regions in proteins associated with neurodegenerative diseases"...

the aggregation of misfolded proteins, thus many chaperone proteins are classified as heat shock proteins, as the tendency for protein aggregation is increased...

major mechanisms for neuronal death in Parkinson's Disease include protein aggregation in Lewy bodies, disruption of autophagy, changes in cell metabolism...

structure prediction can be found at List of protein structure prediction software. Protein aggregation diseases such as Alzheimer's disease and Huntington's...

are dyes used for histology staining and biophysical studies of protein aggregation. For example, thioflavin T is used in the RT-QuIC technique to detect...

correlated with protein aggregation and accumulation of misfolded proteins in inclusion bodies. For many years, protein aggregation was considered a...

proteins can exhibit a wide range of characteristics, from conformational change and loss of solubility or dissociation of cofactors to aggregation due...

transmembrane protein is too thin to match the hydrophobic bilayer thickness (right part of Figure), again this might result in protein aggregation, or changes...

of curli-producing bacteria can also boost formation and aggregation of the amyloid protein Syn in old rats and nematodes. Host inflammation responses...

of proper protein conformation (shape) and prevention of unwanted protein aggregation. By helping to stabilize partially unfolded proteins, HSPs aid in...

Look up aggregation in Wiktionary, the free dictionary. Aggregation may refer to: Aggregation problem (economics) Purchasing aggregation, the joining of...

who is currently the company's Executive Chairman. The company's protein aggregation inhibitors target the underlying pathology of dementia, with the...

Sulfenic acids form disulfides with another protein sulfhydryl group, causing cross-linking and aggregation of proteins. Sulfinic acid and R−S(=O)2−OH derivatives...

potentially toxic aggregates. Misfolded proteins, if left unchecked, can lead to aggregation that prevents the protein from moving into its proper conformation...

PMID 16313516. S2CID 24329326. Ross CA, Poirier MA (July 2004). "Protein aggregation and neurodegenerative disease". Nature Medicine. 10 (7 Suppl): S10...

merely a reflection of the loss of protein homeostasis, the balance between synthesis, folding, aggregation and protein turnover. Recently the European Medicines...

predict aggregation rates of proteins using physico-chemical properties. The method reproduces to a remarkable extent the changes of aggregation rates observed...

yeast, prionogenic proteins have a portable prion domain that is both necessary and sufficient for self-templating and protein aggregation. This has been...

neurodegenerative diseases. It is an inhibitor of protein aggregation, particularly preventing the aggregation of α-synuclein which is implicated in the development...

other nerves are compromised by protein aggregation and/or amyloid fibril formation. The aggregation of one precursor protein leads to peripheral neuropathy...

electrostatic forces form when proteins are dissolved in an electrolyte solution. These repulsive forces between proteins prevent aggregation and facilitate dissolution...

PMID 8550493. Goyal K, Walton LJ, Tunnacliffe A (2005). "LEA proteins prevent protein aggregation due to water stress". Biochemical Journal. 388 (Pt 1): 151–157...

Prion Diseases: From Kuru to Variant Creutzfeldt-Jakob Disease". Protein Aggregation and Fibrillogenesis in Cerebral and Systemic Amyloid Disease. Subcellular...

program for discontinuous molecular dynamics simulation of protein folding and aggregation". Computer Physics Communications. 247: 106873. Bibcode:2020CoPhC...

relative efficiency in denaturing a reference protein. At high salt concentrations lysozyme protein aggregation obeys the Hofmeister series originally observed...

Hsp70. Pathological protein aggregation is a major hallmark of multiple neurodegenerative diseases. O-GlcNAc on various proteins has been found to play...

tauopathy, synucleinopathy, and the aggregation of superoxide dismutase-1 (SOD1), polyglutamine, and TAR DNA-binding protein-43 (TDP-43). In all of these instances...

embryogenesis abundant proteins (LEA proteins) are proteins in plants, and some bacteria and invertebrates, that protect against protein aggregation due to desiccation...