Protein backbone fragment libraries have been used successfully in a variety of structural biology applications, including homology modeling, de novo...

genetic engineering, and protein engineering, and the applications of these libraries depend on the source of the original DNA fragments. There are differences...

The Klenow fragment is a large protein fragment produced when DNA polymerase I from E. coli is enzymatically cleaved by the protease subtilisin. First...

A myeloma protein is an abnormal antibody (immunoglobulin) or (more often) a fragment thereof, such as an immunoglobulin light chain, that is produced...

interaction, increasing the combinatorial advantage of a fragment library even further. Druglikeness Protein-directed dynamic combinatorial chemistry Lipinski's...

prediction of new protein structures. Methods for protein structure prediction fall under one of the four following classes: ab initio, fragment based methods...

study of protein–protein, protein–peptide, and protein–DNA interactions that uses bacteriophages (viruses that infect bacteria) to connect proteins with the...

molecular mechanics modeling Modelling biological systems Protein fragment library Lattice proteins Statistical potential "Index of /downloads/psipred". bioinfadmin...

The variable regions are often constructed with the help of a protein fragment library. The segment-matching method divides the target into a series of...

polymerase α, which impairs the editing of the Okazaki fragment sequence and incorporation of the protein into the genetic material. Both alterations can lead...

prion protein (PrP) is encoded in the human body by the PRNP gene also known as CD230 (cluster of differentiation 230). Expression of the protein is most...

protein structure prediction Molecular design software Molecular modeling software Modelling biological systems Fragment libraries Lattice proteins Statistical...

interrogation of libraries via affinity selection, typically on an immobilized protein target. A homogeneous method for screening DNA-encoded libraries (DELs) has...

protein-fragment complementation assay. Pioneered by Stanley Fields and Ok-Kyu Song in 1989, the technique was originally designed to detect protein–protein...

act on the amyloid-beta precursor protein (APP) to cleave the protein into three fragments.[citation needed] Sequential cleavage by beta-secretase 1 (BACE)...

many commercial meat tenderizers. Papain belongs to a family of related proteins, known as the papain-like protease family, with a wide variety of activities...

of protein structure prediction software summarizes notable used software tools in protein structure prediction, including homology modeling, protein threading...

technology typically used to validate protein interactions. It is based on the association of fluorescent protein fragments that are attached to components...

are fragmented and then recombined. DNA shuffling utilizes random recombination as opposed to site-directed mutagenesis in order to generate proteins with...

fragments are separated by electrophoresis using an electric current to move them through a sieve-like gel or matrix, which allows smaller fragments to...

investigating the structure and biological activity of DNA, RNA, and protein molecules, and for protein engineering. Site-directed mutagenesis is one of the most...

Fusion proteins or chimeric (kī-ˈmir-ik) proteins (literally, made of parts from different sources) are proteins created through the joining of two or...

infections. These chimeric proteins are usually made of a modified antibody or antibody fragment, attached to a fragment of a toxin. The targeting portion...

which protein binds to a particular DNA fragment. Bacterial one-hybrid system (B1H) is used to identify which protein binds to a particular DNA fragment. Structure...

cleavage due to protein binding. The control sample, which lacks protein binding, will undergo random cleavage that creates a distinct fragment pattern observed...

The neonatal fragment crystallizable (Fc) receptor (also FcRn, IgG receptor FcRn large subunit p51, or Brambell receptor) is a protein that in humans...

b-fragments. A-fragments form distinct structural domains of approximately 76 amino acids, coded for by a single exon within the complement protein gene...

PCR can also be used to determine whether a particular DNA fragment is found in a cDNA library. PCR has many variations, like reverse transcription PCR...

Amyloid-beta precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. It functions...

the observed fragment masses to match with a database of predicted masses for one of many given peptide sequences. Tandem MS of whole protein ions has been...