lymphocyte-specific protein encoded by the RAG2 gene on human chromosome 11. Together with the RAG1 protein, RAG2 forms a V(D)J recombinase, a protein complex...

are conserved sequences of noncoding DNA that are recognized by the RAG1/RAG2 enzyme complex during V(D)J recombination in immature B cells and T cells...

receptor molecules. There are two recombination-activating genes RAG1 and RAG2, whose cellular expression is restricted to lymphocytes during their developmental...

RAG-1 is a protein that in humans is encoded by the RAG1 gene. The RAG1 and RAG2 genes are largely conserved in humans. 55.99% and 55.98% of the encoded amino...

of T-cells (and B-cells) such as recombination activating genes (RAG1 and RAG2), Interleukin-7 receptor-α (IL7Rα), DCLRE1C-Artemis, RMRP-CHH, DNA-Ligase...

of the major groups of catfish (Teleostei: Siluriformes) using rag1 and rag2 nuclear gene sequences". Mol Phylogenet Evol. 41 (3): 636–62. Bibcode:2006MolPE...

S2CID 40771963. van Gent, Dik; Ramsden, Dale; Gellert, Martin (1996). "The RAG1 and RAG2 Proteins Establish the 12/23 Rule in V(D)J Recombination". Cell. 85 (1):...

NEIL3, TMEM173, ADAR1, NRAS, SAMHD1, SOS1, FASLG, FAS receptor gene, RAG1, RAG2, DNASE1, SHOC2, KRAS, PTPN11, PTEN, BLK, RNASEH2A, RNASEH2B, RNASEH2C, Complement...

complete defects in the immune system have been constructed (e.g. RAG1 and RAG2 knockout mice). For these reasons, nude mice are less popular in research...

DN2 stage (CD44+CD25+), cells upregulate the recombination genes RAG1 and RAG2 and re-arrange the TCRβ locus, combining V-D-J recombination and constant...

of the major groups of catfishes (Teleostei: Siluriformes) using rag1 and rag2 nuclear gene sequences". Mol Phylogenet Evol. 41 (3): 636–62. doi:10.1016/j...

genes associated with immunodeficiency diseases include CD40L, CD40, RAG1, RAG2, IL2RG, and ADA. Here is a summary of some methods utilized to identify genetic...

process of V(D)J recombination gene rearrangement stimulated by RAG1 and RAG2 genes. This process is error-prone, and some thymocytes fail to make functional...

of the major groups of catfishes (Teleostei: Siluriformes) using rag1 and rag2 nuclear gene sequences". Mol. Phylogenet. Evol. 41 (3): 636–62. doi:10.1016/j...

this, it has been hypothesized that these proteins, particularly Rag1 and Rag2 are derived from transposable elements. There is evidence suggesting that...

6-pyruvoyltetrahydropterin synthase QSER1: glutamine serine rich protein 1 RAG1/RAG2: recombination activating genes RASSF7: encoding protein Ras association...

Norman–Roberts syndrome RELN recessive Ogden syndrome X P Omenn syndrome RAG1, RAG2 recessive Osteogenesis imperfecta COL1A1, COL1A2, IFITM5 dominant 1:15,000-20...

cells prevents the development of xenogeneic graft-versus-host disease in Rag2-/-gamma c-/- double knockout mice". Transfusion. 46 (9): 1553–60. doi:10...

of the major groups of catfishes (Teleostei: Siluriformes) using rag1 and rag2 nuclear gene sequences". Mol Phylogenet Evol. 41 (3): 636–62. doi:10.1016/j...

rash, slenomegaly, and lymphadenopathy due to a causative mutation in RAG1, RAG2, or, more rarely, one of several other genes. Lymphocyte-variant hypereosinophilia...

first in early pro-B cells in a process that is dependent on the enzymes RAG2 and RAG1. After the recombination of the D and J regions, the cell is now...

innate immunity. In 2001, in another landmark paper, Schreiber reported that RAG2 knockout mice, which lack an adaptive immune system (T and B cells), had...

was sanguivorous and consumed blood. Based on mitochondrial DNA and the RAG2 gene, the spectral bat is most closely related to the monotypic genus Chrotopterus...

of the major groups of catfishes (Teleostei: Siluriformes) using rag1 and rag2 nuclear gene sequences". Mol Phylogenet Evol. 41 (3): 636–62. doi:10.1016/j...

recombination, hairpin-capped double-strand breaks are created by the RAG1/RAG2 nuclease, which cleaves the DNA at recombination signal sequences. These...

of the major groups of catfishes (Teleostei: Siluriformes) using rag1 and rag2 nuclear gene sequences". Molecular Phylogenetics and Evolution. 41 (3): 636–62...

motifs that are structurally similar to recombination activating gene 2 (RAG2), a protein involved in the activation of the V(D)J recombination. This gene...

of the major groups of catfishes (Teleostei: Siluriformes) using rag1 and rag2 nuclear gene sequences". Mol Phylogenet Evol. 41 (3): 636–62. doi:10.1016/j...

and IL-21. Researchers evolved this NSG model by knocking out the RAG1 and RAG2 genes (recombination activation genes), resulting into the RAGnull version...

revision is achieved via reactivation of recombination enzymes RAG1 and/or RAG2 after T cell activation in the periphery and random recombination of their...