The RNA world is a hypothetical stage in the evolutionary history of life on Earth in which self-replicating RNA molecules proliferated before the evolution...

transfer RNA (tRNA), microRNA (miRNA), small interfering RNA (siRNA), small nucleolar RNA (snoRNAs), Piwi-interacting RNA (piRNA), tRNA-derived small RNA (tsRNA)...

Viroids are small single-stranded, circular RNAs that are infectious pathogens. Unlike viruses, they have no protein coating. All known viroids are inhabitants...

RNAs such as microRNAs, siRNAs, piRNAs, snoRNAs, snRNAs, exRNAs, scaRNAs and the long ncRNAs such as Xist and HOTAIR. The number of non-coding RNAs within...

into the now widely accepted RNA world hypothesis. Almost thirty years later, Orgel wrote a lengthy review of the RNA World hypothesis. This review highlighted...

Transfer ribonucleic acid (tRNA), formerly referred to as soluble ribonucleic acid (sRNA), is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides...

current life descends from an RNA world, although other self-replicating and self-catalyzing molecules may have preceded RNA. Other approaches ("metabolism-first"...

filled by RNA, and catalysis was also largely mediated by RNA (that is, by ribozyme counterparts of enzymes). This concept is known as the RNA world hypothesis...

organize itself and emerge in a hypothesized pre-cellular era known as the RNA world. The universal presence of both biological translation mechanism and genetic...

Gilbert's RNA world". Genetics and Molecular Research. 2 (4): 366–375. PMID 15011140. Forterre, Patrick (2005). "The two ages of the RNA world, and the...

demonstrated that RNA can be both genetic material (like DNA) and a biological catalyst (like protein enzymes), and contributed to the RNA world hypothesis,...

acid (or circRNA) is a type of single-stranded RNA which, unlike linear RNA, forms a covalently closed continuous loop. In circular RNA, the 3' and 5'...

In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is...

experiments of self-replicating RNA showed how RNA may have evolved to diverse complex molecules in RNA world conditions. The RNA evolved to a "replicator network...

hypothesis of earlier life-forms based entirely on RNA. These ribozymes could have formed an RNA world in which there were individuals but no species, as...

reflect a common evolutionary origin as part of ribozymes in an ancient RNA world. It has been suggested that the AMP part of the molecule can be considered...

evolutionary emergence of the DNA world. A world of independently self-replicating RNA genomes apparently no longer exists (RNA viruses are dependent on host...

it possessed the genetic code and ribosomes which translated from DNA or RNA to proteins. Although the timing of the LUCA cannot be definitively constrained...

phylogenetic taxonomy of 16S ribosomal RNA, a technique that has revolutionized microbiology. He also originated the RNA world hypothesis in 1967, although not...

6-triaminopyrimidine (TAP), a candidate primordial genetic base under the RNA world hypothesis Twin anemia-polycythemia sequence (TAPS), a form of chronic...

period followed the hypothesized RNA world and ended with the formation of DNA and contemporary proteins. In the RNP world, RNA molecules began to synthesize...

emergence of more complex life (see RNA world). The basic processes of natural selection applicable to short replicating RNA molecules were shown to have the...

first cell. According to the two main models of abiogenesis, RNA world and iron-sulfur world, prebiotic processes existed before the development of the...

other RNA and DNA nucleobases could be obtained through simulated prebiotic chemistry with a reducing atmosphere. The RNA world hypothesis shows how RNA can...

Numerous key discoveries in biology have emerged from studies of RNA (ribonucleic acid), including seminal work in the fields of biochemistry, genetics...

synthesis (messenger RNA translation). Ribosomes link amino acids together in the order specified by the codons of messenger RNA molecules to form polypeptide...

RNA-dependent RNA polymerase (RdRp) or RNA replicase is an enzyme that catalyzes the replication of RNA from an RNA template. Specifically, it catalyzes...

RNA splicing is a process in molecular biology where a newly-made precursor messenger RNA (pre-mRNA) transcript is transformed into a mature messenger...

Small nuclear RNA (snRNA) is a class of small RNA molecules that are found within the splicing speckles and Cajal bodies of the cell nucleus in eukaryotic...

synthetase ribozymes may have emerged first in the RNA world". RNA. 13 (11): 2012–2019. doi:10.1261/rna.658507. PMC 2040096. PMID 17878321. Demanèche, S...