In biochemistry, a rate-limiting step is a reaction step that controls the rate of a series of biochemical reactions. The statement is, however, a misunderstanding...

rate-limiting step. For a given reaction mechanism, the prediction of the corresponding rate equation (for comparison with the experimental rate law)...

In biochemistry, control coefficients are used to describe how much influence a given reaction step has on the flux or concentration of the species at...

steady state is maintained by balancing the rate of substrate provided by a previous step and the rate that the substrate is converted into product,...

the rate-limiting step, which is the step with the highest flux control coefficient. It is rare that the first committed step is in fact the rate-determining...

phosphoenolpyruvate by phosphoenolpyruvate carboxykinase, which is the rate limiting step in the conversion of nearly all the gluconeogenic precursors (such...

pH-dependent conformational change, rather than the chemical step, appears to be rate-limiting in the hammerhead ribozyme cleavage reaction". Journal of...

is often written as V max {\displaystyle V_{\max }} , represents the limiting rate approached by the system at saturating substrate concentration for a...

of L-tryptophan (L-Trp) to N-formyl-L-kynurenine, as the first and rate-limiting step of the kynurenine pathway. L-tryptophan + O2 ⇌ N-formyl-L-kynurenine...

of the polymerase to the template is the rate-limiting step in DNA synthesis[citation needed], the overall rate of DNA replication during S phase of the...

bacteria. The transformation of ammonia to nitrite is usually the rate limiting step of nitrification. Nitrification is an aerobic process performed by...

exactly this flip occurs is debatable. One theory is that, in the rate-limiting step of the mechanism, the cis-aconitate is released from the enzyme, then...

enzyme phosphoenolpyruvate carboxykinase (PEPCK). This reaction is a rate-limiting step in gluconeogenesis: GTP + oxaloacetate → GDP + phosphoenolpyruvate...

systems theory Control coefficient (biochemistry) Flux (metabolism) Moiety conservation Rate-limiting step (biochemistry) Fell D., (1997) Understanding the...

considered to be located at one point only, called the master reaction or rate limiting step. The summation theorem suggests this does not necessarily have to...

diffusion-limited enzyme catalyses a reaction so efficiently that the rate limiting step is that of substrate diffusion into the active site, or product diffusion...

the substrate is the chemical of interest that is being modified. In biochemistry, an enzyme substrate is the material upon which an enzyme acts. When...

ALAS2 catalyze the first step in the process of heme synthesis. It is the first irreversible step and is also rate limiting. This means that the beginning...

amino acid 5-hydroxytryptophan (5-HTP), which is the initial and rate-limiting step in the synthesis of the neurotransmitter serotonin. It is also the...

primary rate-limiting factor of the Calvin cycle during the day. Nevertheless, under most conditions, and when light is not otherwise limiting photosynthesis...

Robert E. MacKenzie (1998). "Methenyltetrahydrofolate Cyclohydrolase Is Rate Limiting for the Enzymatic Conversion of 10-Formyltetrahydrofolate to 5...

overall rate constant k for a two-step reaction A ⇌ B, B → C is given by k = k2K1, where k2 is the rate constant of the rate-limiting slow second step and...

acetoacetyl-CoA to form 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) which is the rate-limiting step controlling the synthesis of cholesterol. Cholesterol can be used...

freely permeable to glucose, and the initial rate of phosphorylation of glucose is the rate-limiting step in glucose metabolism by the liver. The liver's...

and epinephrine (adrenaline). Tyrosine hydroxylase catalyzes the rate limiting step in this synthesis of catecholamines. In humans, tyrosine hydroxylase...

metabolism pathway. Pyridoxine 5′-phosphate oxidase catalyzes the final, rate-limiting step in vitamin B6 metabolism, the biosynthesis of pyridoxal 5′-phosphate...

to represent the rate-limiting step in the direction of aldehyde reduction. As the rate of coenzyme release limits the catalytic rate, it can be seen that...

Illustrated Biochemistry. New York: Lange Medical Books/McGraw-Hill. ISBN 978-0-07-146197-9. Van Holde KE, Mathews CK (1996). Biochemistry. Menlo Park...

the rate-limiting step of gluconeogenesis. Glucose-6-phosphate is formed from fructose 6-phosphate by phosphoglucoisomerase (the reverse of step 2 in...

(3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, official symbol HMGCR) is the rate-limiting enzyme (NADH-dependent, EC 1.1.1.88; NADPH-dependent, EC 1.1.1.34) of...