Selective estrogen receptor modulators (SERMs), also known as estrogen receptor agonists/antagonists (ERAAs), are a class of drugs that act on estrogen...
58 KB (6,598 words) - 00:02, 14 July 2025
Estrogen receptors (ERs) are proteins found in cells that function as receptors for the hormone estrogen (17β-estradiol). There are two main classes of...
38 KB (4,144 words) - 05:35, 28 June 2025
Selective glucocorticoid receptor agonists. Selective receptor modulator Selective androgen receptor modulator Selective estrogen receptor modulator Selective...
25 KB (2,563 words) - 12:41, 12 July 2025
Selective androgen receptor modulators (SARMs) are a class of drugs that selectively activate the androgen receptor in specific tissues, promoting muscle...
74 KB (6,714 words) - 19:02, 22 May 2025
A selective progesterone receptor modulator (SPRM) is an agent that acts on the progesterone receptor (PR), the biological target of progestogens like...
47 KB (5,156 words) - 23:57, 6 June 2025
A selective estrogen receptor degrader or downregulator (SERD) is a type of drug that selectively binds to the estrogen receptor (ER) and induces its degradation...
6 KB (477 words) - 10:40, 6 July 2025
Classes of selective receptor modulators include: Selective androgen receptor modulator (SARM) Selective estrogen receptor modulator (SERM) Selective glucocorticoid...
2 KB (159 words) - 21:17, 25 March 2025
Clomifene (category Selective estrogen receptor modulators)
unknown cause or who are pregnant. Clomifene is in the selective estrogen receptor modulator (SERM) family of medication and is a nonsteroidal medication...
48 KB (4,759 words) - 22:21, 11 July 2025
Enclomifene (category Selective estrogen receptor modulators)
Name), a nonsteroidal selective estrogen receptor modulator of the triphenylethylene group, acts by antagonizing the estrogen receptor (ER) in the pituitary...
17 KB (1,527 words) - 21:39, 15 July 2025
Raloxifene (category Selective estrogen receptor modulators)
Raloxifene is a selective estrogen receptor modulator (SERM) and therefore a mixed agonist–antagonist of the estrogen receptor (ER). It has estrogenic effects...
46 KB (4,767 words) - 22:02, 29 May 2025
Antiestrogen (redirect from Estrogen receptor antagonists)
include selective estrogen receptor modulators (SERMs) like tamoxifen, clomifene, and raloxifene, the ER silent antagonist and selective estrogen receptor degrader...
8 KB (745 words) - 20:56, 24 November 2024
Ormeloxifene (category Selective estrogen receptor modulators)
centchroman, is one of the selective estrogen receptor modulators, or SERMs, a class of medication which acts on the estrogen receptor. It is best known as...
15 KB (1,292 words) - 18:11, 16 July 2025
Bisphenol A (category Selective estrogen receptor modulators)
hormone receptors, in both humans and animals. It binds to both of the nuclear estrogen receptors (ERs), ERα and ERβ. BPA is a selective estrogen receptor modulator...
67 KB (7,004 words) - 10:52, 11 July 2025
Tamoxifen (category Selective estrogen receptor modulators)
sold under the brand name Nolvadex among others, is a selective estrogen receptor modulator used to prevent breast cancer in women and men. It is also...
88 KB (9,262 words) - 00:51, 17 February 2025
Estrogen receptor beta (ERβ) also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2) is one of two main types of estrogen receptor—a nuclear...
39 KB (4,526 words) - 06:00, 25 July 2024
Enobosarm (category Selective androgen receptor modulators)
MK-2866, and S-22, is a selective androgen receptor modulator (SARM) which is under development for the treatment of androgen receptor-positive breast cancer...
117 KB (12,954 words) - 17:15, 16 July 2025
they bind to and activate estrogen receptors (ERs) which in turn modulate the expression of many genes. Additionally, estrogens bind to and activate rapid-signaling...
74 KB (7,851 words) - 04:08, 15 July 2025
This is a list of selective estrogen receptor modulators (SERMs). SERMs that have been approved for medical use include anordrin (+mifepristone (Zi Yun))...
7 KB (622 words) - 17:05, 6 April 2024
Antihormone therapy (section SERMs (selective estrogen receptor modulator) and SERDs (selective estrogen receptor degrader))
prescribed to selectively block estrogen's effect on certain cells. SERMs like tamoxifen attach to receptors on the cancer cells which blocks estrogen from attaching...
11 KB (1,058 words) - 07:53, 4 January 2025
Etynodiol and estrogen G03FA07 Lynestrenol and estrogen G03FA08 Megestrol and estrogen G03FA09 Noretynodrel and estrogen G03FA10 Norgestrel and estrogen G03FA11...
8 KB (638 words) - 10:26, 20 September 2024
Menopause (redirect from Postmenopausal estrogen deficiency)
derived from a botanical source, that act selectively as agonists or antagonists on the estrogen receptors throughout the body. The most commonly prescribed...
91 KB (10,373 words) - 09:27, 15 July 2025
GnRH modulator, or GnRH receptor modulator, also known as an LHRH modulator or LHRH receptor modulator, is a type of medication which modulates the GnRH...
6 KB (514 words) - 19:52, 27 March 2024
therapy with selective estrogen receptor modulators (SERMs) like tamoxifen and aromatase inhibitors like anastrozole. The use of high-dose estrogen therapy...
131 KB (14,553 words) - 01:41, 12 July 2025
addition, 17β-dihydroequilenin has shown a selective estrogen receptor modulator (SERM)-like profile of estrogenic activity in studies with monkeys, in which...
59 KB (6,489 words) - 22:44, 11 July 2025
S42 is a fully synthetic steroidal selective androgen receptor modulator (SARM) developed for the treatment of muscle wasting in the elderly. MK-4541...
2 KB (202 words) - 17:13, 16 July 2025
Phytoestrogens (e.g., coumestrol, daidzein, genistein, miroestrol) Selective estrogen receptor modulators (e.g., tamoxifen, clomifene, raloxifene) Antiestrogens (e...
58 KB (6,134 words) - 01:39, 12 July 2025
Hormone therapy (redirect from Anti-estrogen therapy)
cancer Estrogen deprivation therapy for women with estrogen receptor-positive breast cancer High-dose estrogen therapy for women with estrogen receptor-positive...
7 KB (757 words) - 21:05, 29 May 2025
Fulvestrant (category Selective estrogen receptor degraders)
Fulvestrant is a selective estrogen receptor degrader (SERD) and was first-in-class to be approved. It works by binding to the estrogen receptor and destabilizing...
27 KB (2,341 words) - 02:26, 12 July 2025
company working on drugs in the selective estrogen receptor modulator (SERM) and selective androgen receptor modulator (SARM) classes. Its drugs in development...
7 KB (627 words) - 22:13, 22 November 2024
Bazedoxifene (category Selective estrogen receptor modulators)
(pending more study) for cancer. It is a third-generation selective estrogen receptor modulator (SERM). Since late 2013 it has had U.S. FDA approval for...
7 KB (491 words) - 20:06, 29 May 2025