Semaphorin-3A is a protein that in humans is encoded by the SEMA3A gene. The SEMA3A gene is a member of the semaphorin family and encodes a protein with...
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Semaphorins are a class of secreted and membrane proteins that were originally identified as axonal growth cone guidance molecules. They primarily act...
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semaphorin 3 family, consisting of human semaphorins 3A-G (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins 3A-G, all have a basic domain at the...
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of apical dendrites of pyramidal cells in cortical layer V towards semaphorin-3A (Sema3a). Whereas the axons of pyramidal cells are repelled by Sema3a...
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remyelination. Sema 4D(Semaphorin 4D) functions through the PlexinB1 receptor and inhibits remyelination. Sema 3A (Semaphorin 3A) is present in the scar...
28 KB (3,575 words) - 19:49, 16 April 2025
repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. In some studies, the PLXNA2 gene is associated with schizophrenia...
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et al. (October 1999). "Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors". Cell. 99 (1): 59–69. doi:10.1016/S0092-8674(00)80062-8....
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Neuropilin-1 interacts with Plexin-A proteins to form the Semaphorin-3A receptor complex. Semaphorin-a3A is then released in the ventral spinal cord to steer...
36 KB (3,347 words) - 17:31, 16 July 2025
Taniguchi, Masahiko; Verhaagen, Joost (2003-12-01). "Meningeal cell-derived semaphorin 3A inhibits neurite outgrowth" (PDF). Molecular and Cellular Neurosciences...
12 KB (1,428 words) - 13:03, 19 July 2024
Nakamura F, et al. (1999). "Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors". Cell. 99 (1): 59–69. doi:10.1016/S0092-8674(00)80062-8....
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A; Yagil, Z; Hagalili, Y; Klein, H; Lerman, O; Behar, O (Jan 2006). "Semaphorin 3A and neurotrophins: a balance between apoptosis and survival signaling...
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axon guidance that involves axonal guidance molecules such as sema3A (semaphorin 3A) and (neuropilin). Neuroangiogenic and axonal guidance molecules act...
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that CRMP-2 played a role in the transduction of the extracellular Semaphorin 3A (Sema3A), an inhibitory protein for axonal guidance in chick dorsal...
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cells control fertility through ovarian-steroid-dependent release of semaphorin 3A". PLOS Biology. 12 (3): e1001808. doi:10.1371/journal.pbio.1001808....
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efferent projections by semaphorin-neuropilin interactions. Science 282:1904-1906. Polleux, F., T. Morrow and A. Ghosh (2000). Semaphorin 3A is a chemoattractant...
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NGFR; Nestin; Netrin-1; Neuropilin; Plexin-A1; RanBPM; Semaphorin 3A; Semaphorin 3F; Semaphorin 4D; Slit2; Slit3; Staufen; Tbr 1; Tbr 2; Trk A; Tubulin...
37 KB (3,890 words) - 09:30, 18 July 2025
The Sema domain is a structural domain of semaphorins, which are a large family of secreted and transmembrane proteins, some of which function as repellent...
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The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)...
133 KB (7,397 words) - 17:48, 16 July 2025
Zion Medical Center and Technion developed a novel molecule called semaphorin 3A that aims to treat inflammatory conditions, including lupus and asthma...
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PMID 18455953. Dent, E. W.; Barnes, AM; Tang, F; Kalil, K (2004). "Netrin-1 and Semaphorin 3A Promote or Inhibit Cortical Axon Branching, Respectively, by Reorganization...
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"Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in Semaphorin 3A-induced cytoskeletal collapse". The Journal of Neuroscience. 22 (2):...
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Rohm B, Rahim B, Kleiber B, Hovatta I, Püschel AW (Dec 2000). "The semaphorin 3A receptor may directly regulate the activity of small GTPases". FEBS...
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Muiswinkel FL, Verhaagen J (2006). "The expression of the chemorepellent Semaphorin 3A is selectively induced in terminal Schwann cells of a subset of neuromuscular...
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retinopathy of prematurity: opposing actions of neuronal factors GPR91 and semaphorins 3A". Acta Paediatrica. 101 (8): 819–26. doi:10.1111/j.1651-2227.2012.02692...
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Nieuwenhuis B, Verhaagen J (2014). "A perspective on the role of class III semaphorin signaling in central nervous system trauma". Frontiers in Cellular Neuroscience...
90 KB (9,842 words) - 21:54, 10 July 2025
Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling" (PDF). Journal of Cell Science. 118 (Pt 20): 4689–700. doi:10...
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interaction between the small GTP-binding protein Rin and the N-terminal of Brn-3a transcription factor". Oncogene. 22 (35): 5408–14. doi:10.1038/sj.onc.1206635...
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looping odontogenesis of dentin-containing tooth positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis multicellular...
16 KB (2,023 words) - 16:48, 17 July 2025