DNA topoisomerase 3-alpha is an enzyme that in humans is encoded by the TOP3A gene. This gene encodes a DNA topoisomerase, an enzyme that controls and...
13 KB (1,648 words) - 23:57, 17 August 2023
the same protein complex to which the BLM gene product belongs, including TOP3A, which encodes the type I topoisomerase, topoisomerase 3 alpha, RMI1, and...
25 KB (2,752 words) - 23:01, 12 February 2025
CHAF1A, CHEK1, FANCM, FEN1, H2AFX, MCM6 MLH1 P53, RAD51L3, RAD51, RPA1, TOP3A, TP53BP1, WRN, and XRCC2. GRCh38: Ensembl release 89: ENSG00000197299 –...
21 KB (2,565 words) - 06:29, 24 September 2024
ALDH3A2, ALDH3A1, SHMT1, ARSA, WNT7B, TNFRSF13B, UPK3A, TYMP, RASD1, PEMT and TOP3A. These genes can potentially serve as metastasis suppressors. In a basal-like...
14 KB (1,578 words) - 21:16, 27 June 2024
Q969P6 17201 TOP2A HGNC:11989 P11388 17202 TOP2B HGNC:11990 Q02880 17203 TOP3A HGNC:11992 Q13472 17204 TOP3B HGNC:11993 O95985 17205 TOP6BL HGNC:26197...
242 KB (17 words) - 18:43, 6 October 2024
autosomal recessive/dominant) POLG, SLC25A4, RNASEH1, TWNK, TK2, POLG2, DGUOK, TOP3A, RRM2B AR/AD PS157640 Mitochondrial DNA depletion syndrome (MNGIE type)...
44 KB (3,591 words) - 18:21, 23 May 2025
AP, Allen JA, Nelson CB, Tomlinson CG, et al. (May 2019). "The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)". Nature...
19 KB (1,914 words) - 04:28, 19 June 2024
CV, Thakur RS, Parry DA, Bizard AH, et al. (August 2018). "Mutations in TOP3A Cause a Bloom Syndrome-like Disorder". American Journal of Human Genetics...
10 KB (970 words) - 10:16, 13 January 2024