Telomerase reverse transcriptase (abbreviated to TERT, or hTERT in humans) is a catalytic subunit of the enzyme telomerase, which, together with the telomerase...
46 KB (5,304 words) - 20:19, 20 October 2024
A reverse transcriptase (RT) is an enzyme used to convert RNA genome to DNA, a process termed reverse transcription. Reverse transcriptases are used by...
27 KB (3,042 words) - 15:04, 8 May 2025
Drosophila melanogaster lacks telomerase, but instead uses retrotransposons to maintain telomeres. Telomerase is a reverse transcriptase enzyme that carries its...
50 KB (5,791 words) - 11:39, 25 March 2025
TERC serves as a template for telomere replication (reverse transcription) by telomerase. Telomerase RNAs differ greatly in sequence and structure between...
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studied telomeres, and his lab discovered an enzyme, TERT (telomerase reverse transcriptase), which is part of the process of restoring telomeres after...
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HeLa (section Telomerase)
cells. Like many other cancer cells, HeLa cells have an active version of telomerase during cell division, which copies telomeres over and over again. This...
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they had been reverse transcribed from any RNA molecule. In contrast to retrotransposons, retroposons never encode reverse transcriptase (RT) (but see...
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oxaloacetate, and ultimately to glucose, in a process that is almost the reverse of glycolysis. The enzymes of the citric acid cycle are located in the...
169 KB (18,655 words) - 17:36, 16 May 2025
potentially involved in cerebral development. The deletion of the telomerase reverse transcriptase (hTERT) gene localized in 5p15.33 may contribute to the phenotypic...
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classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster...
63 KB (6,253 words) - 16:36, 21 May 2025
DNA. They include reverse transcriptase, which is a viral enzyme involved in the infection of cells by retroviruses, and telomerase, which is required...
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S2CID 4164029. Coffin JM, Fan H (September 2016). "The Discovery of Reverse Transcriptase". Annual Review of Virology. 3 (1): 29–51. doi:10...
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classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster...
17 KB (2,054 words) - 03:38, 14 March 2025
classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster...
210 KB (19,668 words) - 00:35, 13 May 2025
classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster...
216 KB (23,062 words) - 13:30, 20 May 2025
classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster...
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will facilitate or inhibit the activity. Although telomerase has telomerase reverse transcriptase as a catalytic subunit, regulation is accomplished...
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classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster...
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mutation in motif D of the reverse transcriptase domain of the telomerase protein, hTERT, leads to this phenotype. Thus telomerase dosage is important for...
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dysplasia (mutations in FoxF1) Mutations in telomerase reverse transcriptase (TERT) Mutations in telomerase RNA component (TERC) Mutations in the regulator...
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classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster...
112 KB (11,084 words) - 17:50, 18 May 2025
classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster...
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classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster...
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classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster...
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Cancer cell (section Telomerase)
features that make them “immortal” according to some researchers. The enzyme telomerase is used to extend the cancer cell's life span. While the telomeres of...
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classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster...
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floor. It is even inferred that LUCA also grew from H2 and CO2 via the reverse incomplete Krebs cycle. Other metabolic pathways inferred in LUCA are the...
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polymerase enzymes. The ribozymes are mutated by reverse transcribing them with reverse transcriptase into various cDNA and amplified with error-prone...
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classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster...
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3-hydroxypropionate/ 4-hydroxybutyrate cycle. The Thermoproteota also use the reverse Krebs cycle while the "Euryarchaeota" also use the reductive acetyl-CoA...
154 KB (16,713 words) - 13:07, 22 May 2025