• Thumbnail for Telomeric repeat-binding factor 1
    Telomeric repeat-binding factor 1 is a protein that in humans is encoded by the TERF1 gene. The human TERF1 gene is located in the chromosome 8 at 73...
    20 KB (2,474 words) - 21:38, 26 May 2025
  • Thumbnail for Telomeric repeat-binding factor 2
    Telomeric repeat-binding factor 2 is a protein that is present at telomeres throughout the cell cycle. It is also known as TERF2, TRF2, and TRBF2, and...
    27 KB (3,340 words) - 22:06, 22 December 2023
  • intermittent fasting Transfer RNA-derived fragment TERF1, Telomeric repeat-binding factor 1 (also known as TRF1) Sandefjord Airport, Torp, Norway, IATA...
    1 KB (155 words) - 05:25, 25 April 2025
  • Thumbnail for Telomeric repeat–containing RNA
    Telomeric repeat–containing RNA (TERRA) is a long non-coding RNA transcribed from telomeres - repetitive nucleotide regions found on the ends of chromosomes...
    46 KB (5,236 words) - 16:00, 22 May 2025
  • Thumbnail for G-quadruplex
    Dash D, Chowdhury S (November 2019). "Telomere Repeat-Binding Factor 2 Binds Extensively to Extra-Telomeric G-quadruplexes and Regulates the Epigenetic Status...
    95 KB (12,021 words) - 13:17, 23 May 2025
  • Thumbnail for Tankyrase
    (Apr 2002). "The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel...
    12 KB (1,493 words) - 17:10, 2 December 2023
  • Thumbnail for TNKS1BP1
    (Apr 2002). "The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel...
    6 KB (663 words) - 04:37, 27 May 2025
  • telomere-binding protein refers to TTAGGG repeat binding factor-1 (TERF1) and TTAGGG repeat binding factor-2 (TERF2). Telomere sequences in humans are...
    13 KB (1,658 words) - 04:45, 30 April 2025
  • Thumbnail for Tankyrase 2
    (2002). "The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel...
    7 KB (822 words) - 06:18, 5 January 2024
  • Thumbnail for HMBOX1
    binds to the double-stranded repeat sequence of telomeres. HMBOX1 has originally been identified to associate with telomeric chromatin in telomerase-positive...
    4 KB (452 words) - 01:09, 9 April 2022
  • Thumbnail for TERF2IP
    Telomeric repeat-binding factor 2-interacting protein 1 also known as repressor activator protein 1 (Rap1) is a protein that in humans is encoded by the...
    9 KB (1,161 words) - 18:14, 7 August 2022
  • Thumbnail for DUX4
    copy of exon 3 is present, telomeric to the D4Z4 repeat array. The open reading frame (ORF) is entirely contained within exon 1 and contains two homeoboxes...
    7 KB (709 words) - 21:41, 1 February 2025
  • Shelterin (category Telomere-binding proteins)
    about ten times more abundant than TPP1 and POT1. TRF1 (Telomere Repeat binding Factor 1): TRF1 is a homodimeric protein that binds to the double-stranded...
    21 KB (2,334 words) - 22:04, 20 September 2024
  • replication problem". In white blood cells, the gradual shortening of telomeric DNA has been shown to inversely correlate with ageing in several sample...
    67 KB (7,410 words) - 04:24, 18 May 2025
  • mating type loci and at yeast telomeres, the transcription factors Abf1 (ARS binding factor) and Rap1 (repressor-activator protein) associate with specific...
    19 KB (2,343 words) - 01:04, 3 December 2023
  • Thumbnail for PIN1
    against decapentaplegic homolog 3 P53, PKMYT1, PLK1, SUPT5H, Telomeric repeat-binding factor 1, and Wee1-like protein kinase. GRCh38: Ensembl release 89:...
    23 KB (2,792 words) - 20:16, 8 April 2024
  • Thumbnail for Nucleolin
    oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Nucleolin is also able to act as a...
    17 KB (1,936 words) - 01:16, 28 July 2024
  • PMID 31072070. Cusanelli E, Chartrand P (May 2014). "Telomeric noncoding RNA: telomeric repeat-containing RNA in telomere biology". Wiley Interdisciplinary...
    42 KB (4,774 words) - 17:56, 3 November 2024
  • MeSH D12.776.660.235.700.750 – telomeric repeat binding protein 1 MeSH D12.776.660.235.700.875 – telomeric repeat binding protein 2 MeSH D12.776.660.352...
    9 KB (356 words) - 16:49, 9 February 2024
  • Thumbnail for Telomere
    Telomere (redirect from Telomeric)
    DNA repair machinery. Should non-homologous end joining occur at the telomeric ends, chromosomal fusion would result. The T-loop is maintained by several...
    46 KB (5,183 words) - 08:05, 28 May 2025
  • Thumbnail for RNA-binding protein FUS
    human telomeric DNA in vitro. Beyond nucleic acid binding, FUS/TLS was also found to associate with both general and more specialized protein factors to...
    32 KB (3,968 words) - 16:01, 6 February 2025
  • vertebrate telomeric DNA consists of long (TTAGGG)n repeats of variable length, often around 3-20kb. Subtelomeres are segments of DNA between telomeric caps...
    23 KB (2,747 words) - 01:10, 27 May 2025
  • VSG genes become activated by gene conversion in a hierarchical order: telomeric VSGs are activated first, followed by array VSGs, and finally pseudogene...
    25 KB (3,270 words) - 12:33, 4 December 2024
  • Thumbnail for POT1
    POT1 (category Telomere-binding proteins)
    Podell ER, Cech TR (December 2004). "Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection". Nature...
    12 KB (1,203 words) - 04:14, 2 June 2025
  • Thumbnail for DNA end resection
    inhibitory effect by binding to telomeric DNA. In the Late S/G2 phase, the protein kinase CDK1 (cyclin-dependent) promotes telomeric resection. This control...
    18 KB (2,277 words) - 13:23, 26 November 2023
  • Thumbnail for Telomerase
    Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA. Nat Struct Mol Biol. 2010 Apr;17(4):513-8 NCBI - telomerase...
    50 KB (5,791 words) - 17:17, 23 May 2025
  • Thumbnail for Long non-coding RNA
    Khoriauli L, Giulotto E, Lingner J (November 2007). "Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends". Science. 318 (5851):...
    105 KB (11,068 words) - 21:49, 7 June 2025
  • Thumbnail for PURA
    number of repeats of this small sequence. N may be repeated up to three times in this sequence. Following the identification of a Pur factor, which specifically...
    34 KB (4,047 words) - 17:10, 25 October 2023
  • Thumbnail for Chromosome 5
    FBXL7: F-box/LRR-repeat protein 7 FCHSD1: FCH and double SH3 domain protein 1 FGF1: fibroblast growth factor 1 (acidic fibroblast growth factor) FGFR4: fibroblast...
    32 KB (2,298 words) - 14:32, 20 April 2025
  • Thumbnail for Copy number variation
    classification based on size of the repeat is the most obvious type of classification as size is an important factor in examining the types of mechanisms...
    46 KB (5,325 words) - 21:58, 12 April 2025