• Thumbnail for Toll-like receptor
    Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system. They are single-spanning receptors usually expressed...
    60 KB (6,685 words) - 09:55, 26 April 2024
  • Thumbnail for Toll-like receptor 10
    Toll-like receptor 10 is a protein that in humans is encoded by the TLR10 gene. TLR10 has also been designated as CD290 (cluster of differentiation 290)...
    6 KB (833 words) - 19:32, 7 September 2023
  • Thumbnail for Toll-like receptor 4
    Toll-like receptor 4 (TLR4), also designated as CD284 (cluster of differentiation 284), is a key activator of the innate immune response and plays a central...
    75 KB (9,082 words) - 21:42, 4 April 2024
  • Thumbnail for Toll-like receptor 8
    Toll-like receptor 8 is a protein that in humans is encoded by the TLR8 gene. TLR8 has also been designated as CD288 (cluster of differentiation 288)....
    9 KB (1,091 words) - 21:43, 4 April 2024
  • Thumbnail for Toll-like receptor 2
    Toll-like receptor 2 also known as TLR2 is a protein that in humans is encoded by the TLR2 gene. TLR2 has also been designated as CD282 (cluster of differentiation...
    22 KB (2,409 words) - 21:42, 4 April 2024
  • Thumbnail for Toll-like receptor 7
    Toll-like receptor 7, also known as TLR7, is a protein that in humans is encoded by the TLR7 gene. Orthologs are found in mammals and birds. It is a member...
    11 KB (1,264 words) - 21:43, 4 April 2024
  • Thumbnail for Toll-like receptor 9
    Toll-like receptor 9 is a protein that in humans is encoded by the TLR9 gene. TLR9 has also been designated as CD289 (cluster of differentiation 289)....
    20 KB (2,551 words) - 21:43, 4 April 2024
  • Thumbnail for Toll-like receptor 3
    Toll-like receptor 3 (TLR3) also known as CD283 (cluster of differentiation 283) is a protein that in humans is encoded by the TLR3 gene. TLR3 is a member...
    9 KB (1,057 words) - 21:43, 4 April 2024
  • Thumbnail for Toll-like receptor 6
    Toll-like receptor 6 is a protein that in humans is encoded by the TLR6 gene. TLR6 is a transmembrane protein, member of toll-like receptor family, which...
    8 KB (1,073 words) - 21:43, 4 April 2024
  • Thumbnail for Toll-like receptor 1
    Toll-like receptor 1 (TLR1) is a member of Toll-like receptors (TLRs), which is a family of pattern recognition receptors (PRRs) that form the cornerstone...
    12 KB (1,377 words) - 21:42, 4 April 2024
  • Thumbnail for Toll-like receptor 5
    Toll-like receptor 5, also known as TLR5, is a protein which in humans is encoded by the TLR5 gene. It is a member of the toll-like receptor (TLR) family...
    19 KB (2,255 words) - 05:11, 7 May 2024
  • Thumbnail for Toll-like receptor 11
    pseudogene. TLR11 belongs to the toll-like receptor (TLR) family and the interleukin-1 receptor/toll-like receptor superfamily. In mice, TLR11 has been...
    11 KB (1,460 words) - 08:55, 8 November 2023
  • include toll like receptors (TLRs) and C-type lectin receptors (CLRs). Cytoplasmic PRRs include NOD-like receptors (NLRs) and RIG-I-like receptors (RLRs)...
    43 KB (5,164 words) - 02:53, 24 May 2024
  • Thumbnail for Toll-interleukin receptor
    protein-protein interactions between the toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins...
    8 KB (839 words) - 21:44, 4 April 2024
  • Thumbnail for NOD-like receptor
    recognition receptors (PRRs), and play key roles in the regulation of innate immune response. NLRs can cooperate with toll-like receptors (TLRs) and regulate...
    14 KB (1,532 words) - 23:00, 21 November 2023
  • Thumbnail for MYD88
    activation through Toll-like receptors (TLRs), which belong to large group of pattern recognition receptors (PRR). In general, these receptors sense common...
    20 KB (2,250 words) - 09:33, 6 April 2024
  • present in the host. They are recognized by toll-like receptors (TLRs) and other pattern recognition receptors (PRRs) in both plants and animals. This allows...
    13 KB (1,476 words) - 12:50, 13 January 2024
  • RIG-I-like receptors (retinoic acid-inducible gene-I-like receptors, RLRs) are a type of intracellular pattern recognition receptor involved in the recognition...
    25 KB (3,011 words) - 17:07, 24 May 2024
  • Thumbnail for Fc receptor
    CD4+ T-cell Response and Up-regulates Toll-like Receptor (TLR) Expression". J. Biol. Chem. 291 (3): 1368–86. doi:10.1074/jbc.M115.684795. PMC 4714221. PMID 26582197...
    42 KB (4,735 words) - 03:31, 26 March 2024
  • Thumbnail for Lymphocyte antigen 96
    binding lipopolysaccharide with Toll-Like Receptor (TLR4). The MD-2 protein appears to associate with toll-like receptor 4 on the cell surface and confers...
    12 KB (1,492 words) - 13:13, 4 April 2024
  • Peters JA (February 2007). "Catalytic receptors: Toll-like receptor family". Br. J. Pharmacol. 150 Suppl 1: S150. doi:10.1038/sj.bjp.0706480. Diagram at scq...
    7 KB (350 words) - 19:02, 13 March 2024
  • wide interleukin-1 receptor (IL-1R) family are characterized by extracellular immunoglobulin-like domains and intracellular Toll/Interleukin-1R (TIR)...
    13 KB (1,572 words) - 21:44, 19 February 2023
  • Thumbnail for TICAM2
    essential for Toll-like receptor 4 signal transduction". Proc. Natl. Acad. Sci. U.S.A. 103 (16): 6299–304. Bibcode:2006PNAS..103.6299R. doi:10.1073/pnas.0510041103...
    4 KB (497 words) - 19:39, 12 May 2024
  • Thumbnail for TICAM1
    interferon-β or TRIF) is an adapter in responding to activation of toll-like receptors (TLRs). It mediates the rather delayed cascade of two TLR-associated...
    4 KB (616 words) - 21:44, 4 April 2024
  • Thumbnail for Receptor (biochemistry)
    receptor that is not responding sufficiently to the hormone. The main receptors in the immune system are pattern recognition receptors (PRRs), toll-like...
    26 KB (2,672 words) - 18:09, 25 April 2024
  • Retrieved 2015-10-13. "IL10RA - Interleukin-10 receptor subunit alpha precursor - Homo sapiens (Human)". www.uniprot.org. Retrieved 2015-10-13. "IL10RB -...
    96 KB (467 words) - 06:58, 14 October 2022
  • components of the Interleukin-1 receptor signaling pathway and some Toll-like receptor signaling pathways. Toll-like receptors (TLRs) detect microorganisms...
    30 KB (3,637 words) - 16:01, 30 March 2024
  • Thumbnail for Nociceptin receptor
    the OPRL1 (opioid receptor-like 1) gene. The nociceptin receptor is a member of the opioid subfamily of G protein-coupled receptors whose natural ligand...
    28 KB (3,337 words) - 09:15, 22 May 2024
  • Thumbnail for IRAK4
    (interleukin-1 receptor-associated kinase 4), in the IRAK family, is a protein kinase involved in signaling innate immune responses from Toll-like receptors. It...
    20 KB (2,530 words) - 07:42, 21 December 2023
  • Thumbnail for (+)-Morphine
    effects by being a selective-agonist of the Toll-like receptor 4 (TLR4), which due to not binding to opioid receptors allows it to effectively reverse the analgesic...
    3 KB (302 words) - 00:52, 18 February 2024