molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information...

Transcription factor Jun is a protein that in humans is encoded by the JUN gene. c-Jun, in combination with protein c-Fos, forms the AP-1 early response...

General transcription factors (GTFs), also known as basal transcriptional factors, are a class of protein transcription factors that bind to specific...

by an inactive transcription factor. Phosphorylation of the transcription factor may activate it and that activated transcription factor may then activate...

Transcription factor Sp1, also known as specificity protein 1* is a protein that in humans is encoded by the SP1 gene. The protein encoded by this gene...

Microphthalmia-associated transcription factor also known as class E basic helix-loop-helix protein 32 or bHLHe32 is a protein that in humans is encoded...

biology. The regulation of transcription is a vital process in all living organisms. It is orchestrated by transcription factors and other proteins working...

This list of manually curated human transcription factors is taken from Lambert, Jolma, Campitelli et al. It was assembled by manual curation. More detailed...

regulate. CREs typically regulate gene transcription by binding to transcription factors. A single transcription factor may bind to many CREs, and hence control...

The fluffy (fl) gene of Neurospora crassa is required for asexual sporulation and encodes an 88 kDa polypeptide containing a typical fungal Zn2Cys6 DNA-binding...

promoters. General transcription factors are a group of proteins involved in transcription initiation and regulation. These factors typically have DNA-binding...

T-box transcription factor T, also known as Brachyury protein, is encoded for in humans and other apes by the TBXT gene. Brachyury functions as a transcription...

(AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and...

sigma factor (σ factor or specificity factor) is a protein needed for initiation of transcription in bacteria. It is a bacterial transcription initiation...

Escargot (esg) is a transcription factor expressed in Drosophila melanogaster. It is responsible for the maintenance of intestinal stem cells and is used...

Transcription factor II B (TFIIB) is a general transcription factor that is involved in the formation of the RNA polymerase II preinitiation complex (PIC)...

A ρ factor (Rho factor) is a bacterial protein involved in the termination of transcription. Rho factor binds to the transcription terminator pause site...

The Gal4 transcription factor is a positive regulator of gene expression of galactose-induced genes. This protein represents a large fungal family of transcription...

Transformation Specific) family is one of the largest families of transcription factors and is unique to animals. There are 28 genes in humans, 27 in the...

molecular biology, transcription factor DP (Dimerization Partner) is a family of proteins which function as transcription factors. DP forms a heterodimer...

polymerase and for proteins called transcription factors that recruit RNA polymerase. These transcription factors have specific activator or repressor...

by regio/stereoselective Michael addition to ring A. NF-κB is a transcription factor that regulates many genes involved in cell survival, growth, immune...

Transcription factor II D (TFIID) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. RNA polymerase...

The GATA transcription factor family consists of six DNA-binding proteins (GATA1-6) that regulates transcription of DNA due to their ability to bind to...

(SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein/transcription factor) encoded by the SRY gene that...

Mitochondrial transcription factor A, abbreviated as TFAM or mtTFA, is a protein that in humans is encoded by the TFAM gene. This gene encodes a mitochondrial...

Transcription factor Sp4 is a protein that in humans is encoded by the SP4 gene. Sp4 transcription factor has been shown to interact with E2F1. GRCh38:...

over extended time. DeltaFosB (ΔFosB), a gene transcription factor, is a critical component and common factor in the development of virtually all forms of...

Pribnow box with the help of the sigma factor protein (σ factor) to start transcription. In eukaryotes, transcription is performed in the nucleus by three...

Transcription factors are proteins that bind genomic regulatory sites. Identification of genomic regulatory elements is essential for understanding the...