• Thumbnail for Tryptamine
    Tryptamine is an indolamine metabolite of the essential amino acid tryptophan. The chemical structure is defined by an indole—a fused benzene and pyrrole...
    55 KB (4,245 words) - 23:15, 23 May 2025
  • Thumbnail for Substituted tryptamine
    Substituted tryptamines, or simply tryptamines, also known as serotonin analogues (i.e., 5-hydroxytryptamine analogues), are organic compounds which may...
    83 KB (2,323 words) - 01:52, 15 June 2025
  • Thumbnail for Pip-Tryptamine
    pip-Tryptamine (pip-T), also known as N,N-pentamethylenetryptamine, N,N-piperidyltryptamine, or 3-(2-piperidinoethyl)indole, is a serotonin receptor modulator...
    9 KB (976 words) - 10:12, 10 April 2025
  • Thumbnail for Indole alkaloid
    include isoprene groups and are thus called terpene indole or secologanin tryptamine alkaloids. Containing more than 4100 known different compounds, it is...
    34 KB (3,389 words) - 17:00, 7 June 2025
  • Thumbnail for List of psychoactive plants
    many (but not all) other psychoactive substances and is not an indole, tryptamine, phenethylamine, anticholinergic (deliriant) or dissociative drug. THC...
    117 KB (7,978 words) - 05:54, 3 June 2025
  • Thumbnail for 6-Fluorotryptamine
    serotonin receptor agonist and monoamine releasing agent (MRA) of the tryptamine family. 6-FT is known to have affinity for the serotonin 5-HT1A and 5-HT2A...
    12 KB (1,142 words) - 21:52, 21 March 2025
  • Thumbnail for 5-Fluorotryptamine
    is a serotonin receptor agonist and monoamine releasing agent of the tryptamine family. 5-FT is known to have affinity for the serotonin 5-HT1A and 5-HT2A...
    12 KB (1,122 words) - 06:48, 27 March 2025
  • Thumbnail for 5-Methyltryptamine
    releasing agent of the tryptamine family that has been used in scientific research. It is related to other 5-substituted tryptamines such as serotonin...
    12 KB (1,165 words) - 11:46, 19 March 2025
  • Thumbnail for 1-Methyltryptamine
    agonist and monoamine releasing agent of the tryptamine family. It is the 1-methyl derivative of tryptamine (T; PAL-235). The drug is known to act as a...
    7 KB (524 words) - 01:41, 28 May 2025
  • condensation of tryptamine with secologanin to form strictosidine in a formal Pictet–Spengler reaction: 3-α(S)-strictosidine + H2O = tryptamine + secologanin...
    14 KB (1,606 words) - 06:29, 3 November 2024
  • Thumbnail for Dimethyltryptamine
    Dimethyltryptamine (category Psychedelic tryptamines)
    N-DMT), is a serotonergic hallucinogen and investigational drug of the tryptamine family that occurs naturally in many plants and animals, including humans...
    175 KB (16,876 words) - 22:24, 15 June 2025
  • Thumbnail for 5-(Nonyloxy)tryptamine
    5-(Nonyloxy)tryptamine (5-NOT) is a tryptamine derivative which acts as a selective agonist at the 5-HT1B receptor. Increasing the O-alkoxy chain length...
    3 KB (178 words) - 17:23, 27 March 2025
  • Thumbnail for Α-Methyltryptamine
    Α-Methyltryptamine (category Psychedelic tryptamines)
    α-Methyltryptamine (αMT, AMT) is a psychedelic, stimulant, and entactogen drug of the tryptamine family. It was originally developed as an antidepressant at Upjohn in...
    48 KB (4,239 words) - 04:48, 15 June 2025
  • Thumbnail for Partial lysergamide
    embedded tryptamine and phenethylamine moieties within its structure, and so some partial ergolines are simple tryptamines, cyclized tryptamines, simple...
    23 KB (1,543 words) - 01:52, 8 June 2025
  • Thumbnail for Pyr-T
    3-(2-pyrrolidinoethyl)indole, is a lesser-known serotonin receptor modulator of the tryptamine family. It is the cyclized derivative of diethyltryptamine (DET) in which...
    10 KB (896 words) - 06:51, 11 June 2025
  • Harmine (category Psychedelic tryptamines)
    of harmine likely begins with L-tryptophan, which is decarboxylated to tryptamine—an intermediate also used in serotonin synthesis—before undergoing a series...
    23 KB (2,309 words) - 02:35, 27 May 2025
  • Thumbnail for 5-MeO-AMT
    5-MeO-AMT (category Psychedelic tryptamines)
    O-dimethylserotonin (α,O-DMS or Alpha-O), is a serotonergic psychedelic of the tryptamine, α-alkyltryptamine, and 5-methoxytryptamine families. It is a derivative...
    34 KB (2,826 words) - 21:47, 26 May 2025
  • Thumbnail for Psilocybin mushroom
    Psilocybin mushroom (category Psychedelic tryptamine carriers)
    harmaline, which inhibit monoamine oxidase (MAO), an enzyme that breaks down tryptamine alkaloids, and have other actions. They occur in different genera, such...
    67 KB (6,965 words) - 09:25, 10 June 2025
  • Thumbnail for 1-Propyl-5-MeO-AMT
    1-propyl-5-methoxy-α-methyltryptamine, is a serotonin receptor modulator of the tryptamine, α-alkyltryptamine, and 5-methoxytryptamine families. It is the 1-propyl...
    6 KB (561 words) - 17:24, 27 March 2025
  • Thumbnail for 5-MeO-DiPT
    5-MeO-DiPT (category Psychedelic tryptamines)
    sometimes as foxy methoxy or simply foxy, is a psychedelic drug of the tryptamine and 5-methoxytryptamine families. It is the 5-methoxy derivative of...
    32 KB (2,534 words) - 19:49, 29 May 2025
  • Thumbnail for BK-NM-AMT
    putative entactogen of the tryptamine, α-alkyltryptamine, and β-ketotryptamine families. Along with certain other tryptamines, such as α-ethyltryptamine...
    11 KB (698 words) - 06:49, 8 May 2025
  • Thumbnail for Amine N-methyltransferase
    ubiquitously present in non-neural tissues and catalyzes the N-methylation of tryptamine and structurally related compounds. More recently, it was discovered that...
    5 KB (540 words) - 20:49, 21 June 2024
  • Thumbnail for 4-HO-MET
    4-HO-MET (category Psychedelic tryptamines)
    or as metocin, is a lesser-known psychedelic drug of the tryptamine family related to psilocin. It is a close structural and functional analogue...
    20 KB (1,288 words) - 02:34, 31 May 2025
  • Thumbnail for Serotonin
    which block conversion of serotonin and other endogenous tryptamines into N-methylated tryptamines, including N-methylserotonin (NMS; norbufotenin), bufotenin...
    173 KB (18,295 words) - 19:45, 2 June 2025
  • Thumbnail for Β-Carboline
    and synthetic compounds. β-Carboline may be thought of as a cyclized tryptamine. The compound has been found to possess a variety of pharmacological activities...
    3 KB (126 words) - 00:56, 26 May 2025
  • Thumbnail for 2-HO-NMT
    is a tryptamine and is the 2-hydroxy analog of N-methyltryptamine (NMT). It is briefly mentioned in Alexander Shulgin's book TiHKAL (Tryptamines I Have...
    2 KB (59 words) - 07:48, 27 March 2025
  • Thumbnail for 2-Methyltryptamine
    receptor agonist of the tryptamine family. It shows dramatically reduced activity at serotonin receptors compared to tryptamine and mixed effects in terms...
    8 KB (669 words) - 00:32, 11 April 2025
  • Thumbnail for 4-Hydroxytryptamine
    4-Hydroxytryptamine (category Tryptamine alkaloids)
    4-HTA), also known as N,N-didesmethylpsilocin, is a naturally occurring tryptamine alkaloid. It is closely related chemically to the neurotransmitter serotonin...
    15 KB (1,340 words) - 12:54, 31 March 2025
  • Thumbnail for Dipropyltryptamine
    Dipropyltryptamine (category Psychedelic tryptamines)
    N-Dipropyltryptamine (DPT) is a psychedelic drug and entheogen belonging to the tryptamine family. Use as a designer drug has been documented by law enforcement...
    18 KB (1,188 words) - 03:55, 5 May 2025
  • Thumbnail for 4-F-5-MeO-pyr-T
    N-pyrrolidinyltryptamine, is a serotonin 5-HT1A receptor agonist of the tryptamine family. It is a derivative of pyr-T and 5-MeO-DMT. 4-F-5-MeO-pyr-T acts...
    8 KB (684 words) - 18:45, 15 June 2025