• Thumbnail for Variant of uncertain significance
    A variant of uncertain (or unknown) significance (VUS) is a genetic variant that has been identified through genetic testing but whose significance to...
    25 KB (2,460 words) - 00:41, 18 October 2024
  • Thumbnail for Beck–Fahrner syndrome
    Beck–Fahrner syndrome (category Disorders of synthesis of DNA, RNA, and proteins)
    and may serve as a tool to confirm the pathogenicity of a TET3 variant of uncertain significance. The management approach for Beck–Fahrner syndrome is...
    21 KB (1,601 words) - 16:40, 30 May 2025
  • Thumbnail for Kiran Musunuru
    Kiran Musunuru (category Perelman School of Medicine at the University of Pennsylvania faculty)
    Musunuru Kiran (2018-12-11). "Functional Annotation of TNNT2 Variants of Uncertain Significance With Genome-Edited Cardiomyocytes". Circulation. 138...
    15 KB (1,428 words) - 15:28, 25 May 2025
  • VUS or Vus may refer to: Variant of uncertain significance in genetic testing Vus (Crna Trava), village in Serbia Vjesnik u srijedu, Croatian newspaper...
    302 bytes (66 words) - 12:42, 23 October 2017
  • Thumbnail for Genome Project–Write
    as of 2004). Among the many goals of GP-Write are the making of cell lines resistant to all viruses and synthesis assembly lines to test variants of unknown...
    7 KB (703 words) - 19:53, 25 May 2025
  • Thumbnail for BRCA mutation
    part of the necessary protein. Suspected deleterious: While nothing is proven, the variation is currently believed to be harmful. Variant of uncertain significance...
    72 KB (8,976 words) - 05:15, 28 May 2025
  • Thumbnail for Variants of SARS-CoV-2
    Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are viruses that, while similar to the original, have genetic changes that are...
    227 KB (21,895 words) - 22:30, 29 May 2025
  • Thumbnail for SARS-CoV-2 Omicron variant
    Omicron (B.1.1.529) is a variant of SARS-CoV-2 first reported to the World Health Organization (WHO) by the Network for Genomics Surveillance in South...
    223 KB (25,434 words) - 22:08, 29 May 2025
  • Thumbnail for McKusick–Kaufman syndrome
    improves diagnostic accuracy and reduces the likelihood of identifying variants of uncertain significance. In cases where other diagnoses are being considered...
    17 KB (1,842 words) - 20:55, 29 May 2025
  • them to study variants of uncertain significance.  Those collaborations have led to gene discovery and have facilitated understanding of rare diseases...
    9 KB (913 words) - 16:52, 25 January 2025
  • Takikawa sea cow (category Pliocene mammals of Asia)
    of by some scientists as a synonym of the Cuesta sea cow (H. cuestae). It is uncertain whether or not the Takikawa sea cow was simply a local variant...
    3 KB (247 words) - 02:54, 6 May 2025
  • Thumbnail for Shapiro–Senapathy algorithm
    "A unified analytic framework for prioritization of non-coding variants of uncertain significance in heritable breast and ovarian cancer". BMC Medical...
    69 KB (6,804 words) - 04:42, 27 April 2024
  • Thumbnail for OMA1
    disease. 3 heterozygous coding sequence variants of uncertain significance were identified in the OMA1 gene in a screen of 190 individuals with Amyotrophic Lateral...
    13 KB (1,519 words) - 17:01, 23 March 2024
  • mathematician Aleksey Krylov around 1908. The main advantage of AIRM over other variants of aggregated indices methods is its ability to cope with poor-quality...
    9 KB (1,132 words) - 21:58, 10 December 2021
  • symbols instead of Ogham letters. Straif is the Irish name of the fourteenth letter of the Ogham alphabet, ᚎ. Old Irish spelling variants are straif, straiph...
    1 KB (209 words) - 16:07, 23 April 2024
  • Thumbnail for The Flatiron (photograph)
    The Flatiron (photograph) (category Photographs in the Metropolitan Museum of Art)
    blue-green (1909), and yellow-green-black (1904–1909; uncertain).: 24  Using different proportions of pigments in each gum process, Steichen was able to...
    12 KB (1,376 words) - 22:38, 9 January 2025
  • Thumbnail for Polymorphism (biology)
    use of the words "morph" or "polymorphism" for what is a visibly different geographical race or variant is common, but incorrect. The significance of geographical...
    31 KB (3,947 words) - 02:58, 10 April 2025
  • Thumbnail for Rock-a-bye Baby
    that the age of the words is uncertain, and that "imaginations have been stretched to give the rhyme significance". They list a variety of claims that...
    10 KB (1,141 words) - 08:56, 19 May 2025
  • Thumbnail for Nine men's morris
    This variant (also called ten men's morris) was invented by Emanuel Lasker, chess world champion from 1894 to 1921. It is based on the rules of nine men's...
    19 KB (2,261 words) - 00:28, 25 April 2025
  • adenocarcinoma. The main sources of tissue sampling are prostatectomy and prostate biopsy.[citation needed] In uncertain cases, a diagnosis of malignancy can be excluded...
    25 KB (1,649 words) - 12:34, 10 August 2024
  • Thumbnail for One-letter word
    have an uncertain status in language theory, dictionaries and social usage. They are sometimes used as book titles, and have been the subject of literary...
    76 KB (7,749 words) - 11:41, 15 May 2025
  • Thumbnail for HMMER
    Smith-Waterman algorithm for aligning two sequences. A profile HMM is a variant of an HMM relating specifically to biological sequences. Profile HMMs turn...
    15 KB (1,612 words) - 09:00, 27 May 2025
  • Thumbnail for Epidermolysis bullosa dystrophica
    require feeding tubes for nutrition. They also have iron-deficiency anemia of uncertain origin, which leads to chronic fatigue.[citation needed] Open wounds...
    13 KB (1,245 words) - 20:45, 29 May 2025
  • Thumbnail for Reptile
    †Drepanosauromorpha (placement uncertain) †Younginiformes (paraphyletic) †Ichthyosauromorpha (placement uncertain) †Thalattosauria (placement uncertain) Sauria Lepidosauromorpha...
    139 KB (14,930 words) - 23:02, 22 May 2025
  • Thumbnail for Sheva Brachot
    a harmonious unit, the blessings are actually a mosaic of Biblical origination. It is uncertain who composed the benedictions in the form recorded in the...
    11 KB (906 words) - 03:06, 25 October 2024
  • Thumbnail for Serum protein electrophoresis
    diagnose or monitor multiple myeloma, a monoclonal gammopathy of uncertain significance (MGUS), or further investigate a discrepancy between a low albumin...
    17 KB (2,212 words) - 18:02, 11 May 2025
  • profession. Of these, religious professional names have been particularly widespread, including Hoxha (a Muslim priest, Sunni or Bektashi, with its variant Hoxhaj)...
    125 KB (3,230 words) - 21:54, 24 May 2025
  • Thumbnail for Gilbert's syndrome
    of the skin or whites of the eyes) may occur. Gilbert syndrome is due to a genetic variant in the UGT1A1 gene which results in decreased activity of the...
    41 KB (4,212 words) - 00:34, 25 May 2025
  • Thumbnail for Flag of Afghanistan
    1927/8. 1928–1929 (possible variant) 1928–1929 (possible variant) 1928–1929 (possible variant) Fifth flag flown under the rule of Amanullah, introduced about...
    49 KB (4,525 words) - 20:27, 27 May 2025
  • Thumbnail for Elder Futhark
    remaining ten runes of uncertain derivation may either be original innovations, or adaptions of otherwise unneeded Latin letters of the classical Latin...
    35 KB (3,952 words) - 17:31, 8 May 2025