The 5-HT2C receptor is a subtype of the 5-HT2 receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Like all 5-HT2...
51 KB (6,133 words) - 17:35, 28 May 2025
5-HT2C receptor agonists are a class of drugs that activate 5-HT2C receptors. They have been investigated for the treatment of a number of conditions including...
49 KB (5,040 words) - 19:49, 29 May 2025
which activates 5-HT1A, 5-HT1D, 5-HT1B, D2 and norepinephrine receptors. LSD (a psychedelic) is a 5-HT1A, 5-HT2A, 5-HT2C, 5-HT5A and 5-HT6 agonist. The...
65 KB (5,273 words) - 08:55, 28 May 2025
entities: the 5-HT2A (formerly known as 5-HT2 or D), the 5-HT2B (formerly known as 5-HT2F) and the 5-HT2C (formerly known as 5-HT1C) receptors. The 5-HT2A receptors...
131 KB (13,680 words) - 11:36, 9 June 2025
5-HT2A receptor 5-HT2B receptor 5-HT2C receptor 5-HT1 receptor 5-HT3 receptor 5-HT4 receptor 5-HT5 receptor 5-HT6 receptor 5-HT7 receptor Category:5-HT2...
2 KB (166 words) - 00:47, 13 May 2022
which acts as a selective 5-HT2C receptor agonist. meta-Chlorophenylpiperazine (mCPP) is a 5-HT2C-preferring serotonin receptor agonist that induces anxiety...
16 KB (1,664 words) - 07:32, 20 February 2025
rats, 5-HT2B was challenging to characterize initially because of its structural similarity to the other 5-HT2 receptors, particularly 5-HT2C. The 5-HT2...
82 KB (7,913 words) - 17:32, 28 May 2025
Serotonin releasing agent (redirect from 5-HT releaser)
extremely potent agonist of the serotonin 5-HT2C receptor and produces robust effects thought to be 5-HT2C receptor-mediated in in animals and humans, such...
72 KB (8,007 words) - 11:26, 6 June 2025
Locomotor activity (section Dopamine receptor agonists)
selective serotonin 5-HT2C receptor agonists WAY-161503 and CP-809101 produce hypolocomotion in rodents. In serotonin 5-HT2C receptor knockout mice, on...
114 KB (12,382 words) - 04:41, 2 June 2025
Trazodone (category H1 receptor antagonists)
5-HT2A and 5-HT2C receptor antagonist, but has about 15-fold greater potency as an antagonist of the 5-HT2A receptor relative to the 5-HT2C receptor....
120 KB (11,110 words) - 22:25, 29 May 2025
Metatone) – also a 5-HT2A receptor antagonist Viloxazine (Qelbree, formerly Vivalan) – also a 5-HT2B receptor antagonist and 5-HT2C receptor agonist Atomoxetine...
18 KB (1,537 words) - 20:49, 7 May 2025
Agomelatine (category 5-HT2C antagonists)
the 5-HT2C receptor (Ki = 631nM) as well as cloned, human 5-HT2B receptors (Ki = 660nM), but has negligible affinity at 5-HT2A receptors [7]. At 5-HT2B...
51 KB (5,205 words) - 06:33, 9 June 2025
receptor antagonist Bretisilocin (GM-2505; 5F-MET; 5-fluoro-N-methyl-N-ethyltryptamine) – serotonin 5-HT2A and 5-HT2C receptor agonist, serotonin 5-HT2B...
151 KB (11,543 words) - 23:22, 9 June 2025
JPC0323 (category 5-HT2C receptor positive allosteric modulators)
3-dihydroxy-2-(hydroxymethyl)propan-2-yl)oleamide, is a dual serotonin 5-HT2C and 5-HT2A receptor positive allosteric modulator related to oleamide. It showed negligible...
6 KB (427 words) - 17:28, 28 May 2025
the 5-HT2C receptor (Ki = 631nM) as well as cloned, human 5-HT2B receptors (Ki = 660nM), but has negligible affinity at 5-HT2A receptors [7]. At 5-HT2B...
111 KB (12,229 words) - 21:34, 29 May 2025
of cAMP, proving that 5-HT1 are primarily inhibitory. There is no 5-HT1C receptor, as it was reclassified as the 5-HT2C receptor. For more information...
5 KB (472 words) - 15:42, 23 May 2025
Mirtazapine (category H1 receptor antagonists)
the drug for the histamine H1, 5-HT2A, and 5-HT2C receptors; exhibiting near exclusive occupation of these receptors at doses ≤15 mg. However, at higher...
90 KB (8,010 words) - 22:44, 8 June 2025
Desmetramadol (category 5-HT2C antagonists)
abnormally high number of 5-HT2C receptors in the prefrontal cortex. There is some mixed evidence that agomelatine, a 5-HT2C antagonist, is an effective...
13 KB (1,222 words) - 00:03, 30 May 2025
Serotonin (redirect from 5-Hydroxytryptamine)
different receptors. Through 5-HT1B receptors, it negatively regulates bone mass, while it does so positively through 5-HT2B receptors and 5-HT2C receptors. There...
173 KB (18,295 words) - 19:45, 2 June 2025
Lorcaserin (category 5-HT2C agonists)
Pharmaceuticals. It reduces appetite by activating serotonin receptor the 5-HT2C receptor in the hypothalamus, a region of the brain which is known to...
28 KB (2,437 words) - 21:22, 29 May 2025
4-Fluoro-DMT (category 5-HT2C agonists)
and dimethyltryptamine (DMT). It is a modestly selective serotonin 5-HT2C receptor full agonist and doesn't appear to produce psychedelic-like effects...
8 KB (635 words) - 07:09, 10 April 2025
The 5HT6 receptor is a subtype of 5HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5HT). It is a G protein-coupled...
29 KB (3,306 words) - 05:19, 25 May 2025
primarily by activation of the serotonin 5-HT2C receptor rather than by activation of the serotonin 5-HT2A receptor. On the other hand, psychedelic-induced...
91 KB (9,940 words) - 18:18, 9 June 2025
CTW0415 (category 5-HT2C receptor positive allosteric modulators)
family, which acts as a selective positive allosteric modulator of the 5-HT2C receptor, with higher potency than older drugs such as VA012. Structure-activity...
3 KB (223 words) - 18:01, 9 June 2025
suppressed by the serotonin 5-HT1A receptor full agonist 8-OH-DPAT, is greatly augmented by the serotonin 5-HT2C receptor antagonist RS-102221, and is...
24 KB (2,334 words) - 18:29, 20 May 2025
Bretisilocin (redirect from 5-fluoro-MET)
acts as a potent and well-balanced serotonin 5-HT2A and 5-HT2C receptor agonist, serotonin 5-HT2B receptor antagonist, and serotonin releasing agent. It...
17 KB (1,443 words) - 12:47, 27 May 2025
norepinephrine, and dopamine releasing agent, weak serotonin 5-HT2A, 5-HT2B, 5-HT2C receptor agonist, entactogen, and weak psychedelic hallucinogen – post-traumatic...
140 KB (12,315 words) - 14:34, 7 June 2025
Aripiprazole (category 5-HT2C agonists)
agonism at the 5-HT2C receptor might be associated with therapeutic potential in obsessive-compulsive disorder, obesity, and depression. 5-HT2C agonism has...
108 KB (9,715 words) - 20:00, 29 May 2025
V1A receptor antagonist – no recent development since 2007 Eltoprazine (DU-28853) – serotonin 5-HT1A and 5-HT1B receptor agonist and serotonin 5-HT2C receptor...
29 KB (2,976 words) - 21:43, 9 June 2025
Flumexadol (category 5-HT2C agonists)
of the serotonin 5-HT1A (pKi = 7.1) and 5-HT2C (pKi = 7.5) receptors and, to a much lesser extent, of the 5-HT2A (pKi = 6.0) receptor. According to Nilsson...
7 KB (522 words) - 14:23, 24 April 2025