higher affinity for 5-HT4 receptors than for other receptors. SB-207,145 radiolabeled with carbon-11 is used as a radioligand for 5-HT4 in positron emission...

highly selective 5-HT4 receptor agonist that can be used to treat certain disorders of gastrointestinal motility. Other 5-HT4 receptor agonists have shown...

5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in...

relation to Parkinson's disease. 5-HT receptor 5-HT1 receptor 5-HT2 receptor 5-HT3 receptor 5-HT4 receptor 5-HT5 receptor GRCh38: Ensembl release 89: ENSG00000158748...

5-HT2A receptor 5-HT2B receptor 5-HT2C receptor 5-HT1 receptor 5-HT3 receptor 5-HT4 receptor 5-HT5 receptor 5-HT6 receptor 5-HT7 receptor Category:5-HT2...

of 5-HT3 receptors in cell lines and native tissues quickly followed. 5-HT1 receptor 5-HT2 receptor 5-HT4 receptor 5-HT5 receptor 5-HT6 receptor 5-HT7...

"The 5-HT4 receptor agonist, tegaserod, is a potent 5-HT2B receptor antagonist in vitro and in vivo". British Journal of Pharmacology. 143 (5): 549–560...

among others, is a medication acting as a selective, high affinity 5-HT4 receptor agonist which targets the impaired motility associated with chronic...

Paliperidone Risperidone 5-HT receptor 5-HT1 receptor 5-HT2 receptor 5-HT3 receptor 5-HT4 receptor 5-HT5 receptor 5-HT6 receptor GRCh38: Ensembl release...

206 nM affinity. SB-699,551 5-HT receptor 5-HT1 receptor 5-HT2 receptor 5-HT3 receptor 5-HT4 receptor 5-HT6 receptor 5-HT7 receptor GRCh38: Ensembl release...

also a precursor of 5-MeO-DMT in some species. 5-MT acts as an agonist of the serotonin 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors. It is an extremely...

articles of the individual subtypes: 5-HT2 receptor 5-HT3 receptor 5-HT4 receptor 5-HT5 receptor 5-HT6 receptor 5-HT7 receptor Hoyer D, Clarke DE, Fozard JR...

The 5-HT4 receptor is thought to play a significant role in both the physiology and pathophysiology of GI tract motility. Therefore, 5-HT4 receptors have...

a bite, due to an excitatory effect the venom has on the serotonin 5-HT4 receptor of sensory nerves. This sensory nerve stimulation causes a cascading...

It is a selective antagonist of the dopamine D2 receptor and an agonist of the serotonin 5-HT4 receptor. Chemically, it is a benzamide and the (S)-(−)-enantiomer...

(October 2005). "Design and synthesis of specific probes for human 5-HT4 receptor dimerization studies" (PDF). Journal of Medicinal Chemistry. 48 (20):...

the serotonin 5-HT1A, 5-HT2A, 5-HT2C, 5-HT3, and 5-HT4 receptors. It is also known to bind with high affinity to other serotonin receptors, including the...

the serotonin 5-HT1 and 5-HT2 receptors, including of the serotonin 5-HT1B receptor, and is also an agonist of the serotonin 5-HT4 receptor. RU-28253 was...

bowel disorders. The neurogenesis is due to mosapride's effect on the 5-HT4 receptor where it acts as an agonist. Its common side effects include dry mouth...

The 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and functions as a G protein-coupled receptor (GPCR)...

sensory transducers that release 5-HT to activate intrinsic (via 5-HT1P and 5-HT4 receptors) and extrinsic (via 5-HT3 receptors) primary afferent nerves. Chemotherapeutic...

BIMU-8 is a drug which acts as a 5-HT4 receptor selective agonist. BIMU-8 was one of the first compounds of this class. The main action of BIMU-8 is to...

bacteria convert dietary tryptophan to tryptamine, which activates 5-HT4 receptors and regulates gastrointestinal motility. Multiple tryptamine-derived...

The 5-HT2C receptor is a subtype of the 5-HT2 receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Like all 5-HT2...

agonist Ulotaront (SEP-856, SEP-363856) – 5-HT1A receptor and TAAR1 agonist Usmarapride (SUVN-D4010) – 5-HT4 receptor partial agonist Pomaglumetad methionil...

D2 receptors with nanomolar affinity (Ki = 28.8 nM), where it is a receptor antagonist, and is also a mixed 5-HT3 receptor antagonist/5-HT4 receptor agonist...

Christ, Josepha; Neumann, Joachim (2017). "Desensitization of the human 5-HT4 receptor in isolated atria of transgenic mice". Naunyn-Schmiedeberg's Archives...

receptor (or 5-HT1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin, also known as 5-HT, a neurotransmitter. 5-HT1A...

and selective 5-HT4 serotonin receptor antagonist (or weak partial agonist), and is used for research into the function of this receptor subtype. Mialet...

which acts as a potent and highly selective agonist for the serotonin receptor 5-HT4. It is in clinical trials for the treatment of gastroparesis. Chedid...