• Thumbnail for Alternative splicing
    Alternative splicing, alternative RNA splicing, or differential splicing, is an alternative splicing process during gene expression that allows a single...
    62 KB (7,817 words) - 02:05, 4 June 2025
  • Thumbnail for RNA splicing
    of RNA splicing occur in nature; the type of splicing depends on the structure of the spliced intron and the catalysts required for splicing to occur...
    38 KB (4,660 words) - 16:36, 26 February 2025
  • Thumbnail for Protein isoform
    However, such transcripts are also produced by splicing errors in a process called "noisy splicing," and are also potentially translated into protein...
    17 KB (2,010 words) - 02:30, 6 November 2024
  • Thumbnail for Primary transcript
    expression. Alternative splicing can be affected by various factors, including mutations such as chromosomal translocation. In prokaryotes, splicing is done...
    22 KB (2,668 words) - 08:52, 16 December 2024
  • Thumbnail for Serine/arginine-rich splicing factor 1
    Serine/arginine-rich splicing factor 1 (SRSF1) also known as alternative splicing factor 1 (ASF1), pre-mRNA-splicing factor SF2 (SF2) or ASF1/SF2 is a...
    21 KB (2,574 words) - 16:59, 7 August 2024
  • Thumbnail for Minigene
    abundance of alternative splicing, which occurs in most human genes, and the specificity in which splicing is carried out in vivo. Splicing is distinctly...
    21 KB (2,427 words) - 08:41, 10 March 2024
  • Thumbnail for SR protein
    SR protein (section Splicing)
    and alternative pre-mRNA splicing, mRNA export, genome stabilization, nonsense-mediated decay, and translation. SR proteins alternatively splice pre-mRNA...
    27 KB (3,443 words) - 03:57, 30 October 2024
  • Thumbnail for RNA-Seq
    multiple alternative splicing modes: exon skipping (most common splicing mode in humans and higher eukaryotes), mutually exclusive exons, alternative donor...
    87 KB (9,425 words) - 07:16, 1 June 2025
  • structure plots of alternative splicing events from .bam, .gtf, and .vcf files. SpliceR An R package for classification of alternative splicing and prediction...
    164 KB (20,394 words) - 15:59, 20 May 2025
  • Thumbnail for RBM10
    chromosome at Xp11.23 in humans. RBM10 is a regulator of alternative splicing. Alternative splicing is a process associated with gene expression to produce...
    54 KB (5,530 words) - 01:38, 19 May 2024
  • exclusion during splicing. These sites are referred to as exonic splicing enhancers (ESEs), exonic splicing silencers (ESSs), intronic splicing enhancers (ISEs)...
    39 KB (4,540 words) - 10:50, 22 May 2025
  • Thumbnail for Spinal muscular atrophy
    due to a variation in a single nucleotide (840.C→T) – undergoes alternative splicing at the junction of intron 6 to exon 8, with only 10–20% of SMN2 transcripts...
    91 KB (10,036 words) - 22:14, 29 May 2025
  • Thumbnail for Circular RNA
    examples of alternative splicing is in the Drosophila DSCAM gene, which can give rise to approximately 30 thousand distinct alternatively spliced isoforms...
    56 KB (6,708 words) - 06:38, 2 June 2025
  • Thumbnail for Alberto Kornblihtt
    is an Argentine molecular biologist who specializes in alternative ribonucleic acid splicing. During his postdoctoral training with Francisco Baralle...
    20 KB (2,229 words) - 22:32, 26 May 2025
  • mRNA. Alternative splicing is a mechanism by which different proteins can be produced from a single gene by means of using alternative splicing sites...
    50 KB (5,920 words) - 09:41, 3 June 2025
  • Thumbnail for RBFOX1
    The primary function is regulation of alternative splicing of associated genes. Several alternatively spliced transcript variants have been found for...
    31 KB (3,551 words) - 20:19, 26 May 2025
  • Intron (category RNA splicing)
    relevant, alternative splicing and processing noise due to splicing errors. One of the central issues in the field of alternative splicing is working out the...
    47 KB (5,853 words) - 21:36, 25 April 2025
  • Thumbnail for Sex-lethal
    of splicing factors. In D. melanogaster, Sxl exerts its effects primarily through post-transcriptional regulation, specifically alternative splicing and...
    10 KB (1,286 words) - 02:44, 28 May 2025
  • still remains an important challenge. As a consequence, the role of alternative splicing in molecular biology remains largely elusive. Third generation sequencing...
    33 KB (4,024 words) - 23:03, 6 June 2025
  • at the University of Montpellier, specializing in RNA metabolism, alternative splicing, and RNA-based therapeutic strategies. Tazi obtained a Ph.D. in molecular...
    8 KB (771 words) - 20:44, 9 June 2025
  • to a sequence could impact splicing, this process may result in changing the identity of introns and exons; alternatively, the sequence may retain its...
    17 KB (2,076 words) - 18:51, 9 June 2025
  • translation of messenger RNA. Splicing is the process by which non-coding regions of RNA are removed. The number and combination of splicing events varies greatly...
    17 KB (2,074 words) - 04:58, 29 October 2024
  • alternative splicing compared to genes that code a single isoform. This is because alternatively spliced mRNAs are enriched in METTL3 binding sites. Splicing is...
    61 KB (7,733 words) - 15:59, 28 April 2025
  • Thumbnail for Mature messenger RNA
    which cleaves the RNA at the splicing site and recombines the exons of the RNA. Similar to polyadenylation, alternative splicing can occur, resulting in several...
    6 KB (596 words) - 01:14, 26 May 2025
  • Alternative Splicing Annotation Project (ASAP) in computational biology was a database for alternative splicing data maintained by the University of California...
    2 KB (151 words) - 22:12, 6 February 2022
  • Thumbnail for TNNT3
    alternative splicing of multiple exons to generate fsTnT variants, two-dimensional gel electrophoresis detected more than 40 different fsTnT splice forms...
    16 KB (1,961 words) - 02:10, 27 May 2025
  • Thumbnail for Exitron
    Exitron (category RNA splicing)
    Exitrons (exonic introns) are produced through alternative splicing and have characteristics of both introns and exons, but are described as retained introns...
    10 KB (1,317 words) - 09:15, 11 September 2024
  • Thumbnail for Cav1.3
    pacemaking. Post-transcriptional alternative splicing of Cav1.3 is an extensive and vital regulatory mechanism. Alternative splicing can significantly affect...
    27 KB (3,339 words) - 19:57, 9 June 2025
  • Thumbnail for Immunoglobulin D
    diverse with amplifications of Cδ exons. Different splice variants exist due to alternative splicing. In humans and primates, IgD has three Cδ domains...
    17 KB (2,096 words) - 13:22, 25 May 2025
  • transcribed into mRNA, the MAFA strand was also found to undergo alternative splicing which has allowed various forms of the MAFA protein to be translated...
    13 KB (1,840 words) - 02:56, 19 June 2024